Patents by Inventor Pramod Joshi

Pramod Joshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocycles useful as modulators of ion channels
    Patent number: 7880008
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: February 1, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Dean Wilson, Andreas Termin, Lev T. D. Fanning, Paul Krenitsky, Pramod Joshi
  • Pyrimidines and pyrazines useful as modulators of ion channels
    Patent number: 7858786
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: December 28, 2010
    Assignee: Vertex Pharmaceuticals Incoropated
    Inventors: Dean Wilson, Andreas Termin, Dewey Fanning, Paul Krenitsky, Pramod Joshi, Urvi Sheth
  • CGRP receptor antagonists
    Patent number: 7842686
    Abstract: The present invention relates to CGRP receptor antagonists, pharmaceutical compositions thereof, and methods therewith for treating CGRP receptor-mediated diseases and conditions.
    Type: Grant
    Filed: January 21, 2009
    Date of Patent: November 30, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Corey Don Anderson, Andreas P. Termin, Pramod Joshi, Sara S. Hadida Ruah, Daniele Bergeron, Sanghee Yoo, Jingrong Cao
  • CGRP receptor antagonists
    Patent number: 7834000
    Abstract: The present invention relates to CGRP receptor antagonists, pharmaceutical compositions thereof, and methods therewith for treating CGRP receptor-mediated diseases and conditions.
    Type: Grant
    Filed: June 13, 2007
    Date of Patent: November 16, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Corey Gutierrez, Andreas Termin, Sara Hadida-Ruah, Pramod Joshi, Daniele Bergeron, Sanghee Yoo, Hayley Binch, Jon Come, Jingrong Cao, Suganthi Nanthakumar
  • Quinolines Useful as Modulators of ION Channels
    Publication number: 20100137331
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: February 2, 2010
    Publication date: June 3, 2010
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Andreas Termin, Dean Wilson, Pramod Joshi
  • Biaryls useful as modulators of ion channels
    Patent number: 7705002
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: April 27, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Andreas Termin, Dean Wilson, Lev T. D. Fanning, Paul Krenitsky, Pramod Joshi
  • Pyridines useful as modulators of ion channels
    Patent number: 7683065
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: March 23, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Dean Wilson, Andreas Termin, Dewey Fanning, Paul Krenitsky, Pramod Joshi
  • Isoquinolines useful as modulators of ion channels
    Patent number: 7683066
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: March 23, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Andreas Termin, Dean Wilson, Pramod Joshi
  • Quinazolines useful as modulators of ion channels
    Publication number: 20090312342
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: March 3, 2006
    Publication date: December 17, 2009
    Inventors: Dean Wilson, Andreas Termin, Jesus Gonzalez, Lev Fanning, Timothy Neubert, Paul Krenitsky, Pramod Joshi, Dennis Hurley, Urvi Sheth
  • CGRP RECEPTOR ANTAGONISTS
    Publication number: 20090186882
    Abstract: The present invention relates to CGRP receptor antagonists, pharmaceutical compositions thereof, and methods therewith for treating CGRP receptor-mediated diseases and conditions.
    Type: Application
    Filed: January 21, 2009
    Publication date: July 23, 2009
    Inventors: Corey Don Anderson, Andreas P. Termin, Pramod Joshi, Sara S. Hadida Ruah, Daniele Bergeron, Sanghee Yoo
  • CGRP RECEPTOR ANTAGONISTS
    Publication number: 20090176769
    Abstract: The present invention relates to CGRP receptor antagonists, pharmaceutical compositions thereof, and methods therewith for treating CGRP receptor-mediated diseases and conditions.
    Type: Application
    Filed: December 13, 2007
    Publication date: July 9, 2009
    Inventors: Corey Anderson, Andreas Termin, Sara Hadida-Ruah, Pramod Joshi, Sanghee Yoo, Daniele Bergeron, Hayley Binch, Jon Come, Jingrong Cao, Suganthi Nanthakumar, Elaine Krueger, John Maxwell, Arnaud Le Tiran, Yusheng Liao
  • ARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
    Publication number: 20090118338
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 10, 2008
    Publication date: May 7, 2009
    Inventors: Weichuan Caroline Chen, Paul Krenitsky, Pramod Joshi, Andreas Termin, Dean Wilson
  • HETEROARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
    Publication number: 20090099233
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 10, 2008
    Publication date: April 16, 2009
    Inventors: Pramod Joshi, Paul Krenitsky, Andreas Termin, Dean Wilson
  • Digital x-ray detectors
    Patent number: 7488946
    Abstract: An x-ray detector is provided for use in imaging systems. The x-ray detector includes a detector subsystem configured to output electrical signals in response to reception of x-rays. The x-ray detector also includes a single-piece protective enclosure having at least one opening to receive the detector subsystem.
    Type: Grant
    Filed: October 3, 2006
    Date of Patent: February 10, 2009
    Assignee: General Electric Company
    Inventors: William Andrew Hennessy, Bruce Courtney Campbell Amm, Donald Earl Castleberry, Shashishekara Sitharamarao Talya, Virendra Vilas Gaikwad, Shailendra Pramod Joshi, Habib Vafi, Michael John Utschig
  • Heterocycles useful as modulators of ion channels
    Publication number: 20080255147
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 26, 2006
    Publication date: October 16, 2008
    Inventors: Dean Wilson, Andreas Termin, Lev T.D. Fanning, Paul Krenitsky, Pramod Joshi
  • Quinazolines useful as modulators of voltage gated ion channels
    Publication number: 20080221137
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: November 13, 2006
    Publication date: September 11, 2008
    Inventors: Dean Wilson, Lev T.D. Fanning, Paul Krenitsky, Andreas Termin, Pramod Joshi, Urvi Sheth
  • QUINAZOLINES USEFUL AS MODULATORS OF VOLTAGE GATED ION CHANNELS
    Publication number: 20080167305
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: March 18, 2008
    Publication date: July 10, 2008
    Inventors: Dean Wilson, Lev T.D. Fanning, Paul Krenitsky, Andreas Termin, Pramod Joshi, Urvi Sheth
  • Biaryls useful as modulators of ion channels
    Publication number: 20080090837
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 15, 2006
    Publication date: April 17, 2008
    Inventors: Andreas Termin, Dean Wilson, Lev Fanning, Paul Krenitsky, Pramod Joshi
  • Digital x-ray detectors
    Publication number: 20080078939
    Abstract: An x-ray detector is provided for use in imaging systems. The x-ray detector includes a detector subsystem configured to output electrical signals in response to reception of x-rays. The x-ray detector also includes a single-piece protective enclosure having at least one opening to receive the detector subsystem.
    Type: Application
    Filed: October 3, 2006
    Publication date: April 3, 2008
    Inventors: William Andrew Hennessy, Bruce Courtney Campbell Amm, Donald Earl Castleberry, Shashishekara Sitharamarao Talya, Virendra Vilas Gaikwad, Shailendra Pramod Joshi, Habib Vafi, Michael John Utschig
  • Apparatus and Method for Producing Embossed Film
    Publication number: 20080001316
    Abstract: Disclosed herein are embossing lines and methods for their use. In one embodiment an embossing line comprises: an embossing belt disposed about a heating roll and a chill roll, a joining roll disposed between the heating roll and the chill roll, and a pre-embossing heater disposed between the joining roll and the heating roll such that the substrate film can be heated by the pre-embossing heater prior to the embossing belt contacting the heating roll. In another embodiment, a film making process is disclosed.
    Type: Application
    Filed: June 29, 2006
    Publication date: January 3, 2008
    Inventors: Sanjog Shyam Jain, Narasimha Acharya, Shailendra Pramod Joshi, Ashwit Dias, Nitin Vaish