Patents by Inventor Pran K. Datta

Pran K. Datta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purified and isolated serine-threonine kinase receptors associated protein and use of same in the modulation of the biological activity of TGF-&bgr;
    Patent number: 6770458
    Abstract: Isolated and purified proteins and nucleic acids which modulate TGF-&bgr; biological activity, including TGF-&bgr; signal transduction. Particularly, a novel serine-threonine kinase receptors associated protein (STRAP) and cDNA encoding the same are disclosed. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to STRAP, and methods of producing the same, are also disclosed. STRAP is characterized as having TGF-&bgr; modulating activity. Thus, therapeutic methods involving this activity are also disclosed.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: August 3, 2004
    Assignee: Vanderbilt University
    Inventors: Pran K. Datta, Harold L. Moses