Patents by Inventor Pranab K. Gupta

Pranab K. Gupta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 9-?-anomeric nucleoside analogs
    Patent number: 6884880
    Abstract: A process for substantially enhancing the regio and stereoselective synthesis of 9-?-anomeric nucleoside analogs is described. The introduction of the sugar moiety onto a 6-substituted purine base was preformed so that only the 9-?-D- or L-purine nucleoside analogs were obtained. This regio and stereoselective introduction of the sugar moiety allows the synthesis of nucleoside analogs and in particular 2?-deoxy, 3?-deoxy, 2?-deoxy-2?-?-fluoro and 2?,3?-dideoxy-2?-?-fluoro purine nucleoside analogs in high yield without virtually any formation of the 7-positional isomers. The compounds are drugs or intermediates to drugs.
    Type: Grant
    Filed: August 21, 2002
    Date of Patent: April 26, 2005
    Assignee: Ash Stevens, Inc.
    Inventors: Pranab K. Gupta, Stephen A. Munk
  • Process for the preparation of 9-beta-anomeric nucleoside analogs
    Publication number: 20040039190
    Abstract: A process for substantially enhancing the regio and stereoselective synthesis of 9-&bgr;-anomeric nucleoside analogs is described. The introduction of the sugar moiety onto a 6-substituted purine base was preformed so that only the 9-&bgr;-D- or L-purine nucleoside analogs were obtained. This regio and stereoselective introduction of the sugar moiety allows the synthesis of nucleoside analogs and in particular 2′-deoxy, 3′-deoxy, 2′-deoxy-2′-&bgr;-fluoro and 2′,3′-dideoxy-2′-&bgr;-fluoro purine nucleoside analogs in high yield without virtually any formation of the 7-positional isomers. The compounds are drugs or intermediates to drugs.
    Type: Application
    Filed: August 21, 2002
    Publication date: February 26, 2004
    Applicant: Ash Stevens, Inc.
    Inventors: Pranab K. Gupta, Stephen A. Munk