Patents by Inventor Pranab Mukherjee

Pranab Mukherjee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Probiotic controlling fungi and uses thereof
    Patent number: 9987316
    Abstract: A method for controlling detrimental oral organisms in various individuals includes administering a priobiotic composition that includes one or more species or strains of beneficial fungi and/or one or more compounds produced therefrom that control one or more species of detrimental oral bacteria and/or other organisms.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: June 5, 2018
    Assignee: Case Western Reserve University
    Inventors: Mahmoud A. Ghannoum, Pranab Mukherjee
  • PROBIOTIC CONTROLLING FUNGI AND USES THEREOF
    Publication number: 20140186318
    Abstract: A method for controlling detrimental oral organisms in various individuals includes administering a priobiotic composition that includes one or more species or strains of beneficial fungi and/or one or more compounds produced therefrom that control one or more species of detrimental oral bacteria and/or other organisms.
    Type: Application
    Filed: September 16, 2013
    Publication date: July 3, 2014
    Applicant: Case Western Reserve University
    Inventors: Mahmoud A. Ghannoum, Pranab Mukherjee
  • PHTHALOCYANINE-BASED ANTIFUNGAL AGENTS
    Publication number: 20120265121
    Abstract: A method is described for the photodynamic treatment of a fungal infection in a subject by administering a therapeutically effective amount of a phthalocyanine compound or a pharmaceutically acceptable salt thereof to the subject and activating the phthalocyanine compound with light. The method is useful for treating various dermatophyte infections such as onychomycosis, and in particular fungal infection by Candida and Trichophyton.
    Type: Application
    Filed: March 19, 2012
    Publication date: October 18, 2012
    Applicant: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Elma D. Baron, Kevin D. Cooper, Minh Lam, Pranab Mukherjee, Mahmoud A. Ghannoum, Nancy L. Oleinick
  • Neuroprotectin D1 protects against cellular apoptosis, stroke damage, alzheimer's disease and retinal diseases
    Publication number: 20050075398
    Abstract: A unique DHA product, 10, 17S-docosatriene (“Neuroprotectin D1” or “NPD1”), was found to provide surprisingly effective neuroprotection when administered right after an experimental stroke. Moreover, both nerve cells and retinal pigment epithelial (RPE) cells were found to synthesize 10,17S-docosatriene (NPD1) from DHA. NPD1 also potently counteracted H2O2/TNF? oxidative stress-mediated cell apoptotic damage. Under the same oxidative-stress conditions, NPD1 up-regulated the anti-apoptotic Bcl-2 proteins, Bcl-2 and Bcl-xL, and decreased expression of the pro-apoptotic proteins, Bad and Bax. Moreover, in RPE cells NPD1 inhibited oxidative stress-induced caspase-3 activation, IL-1?-stimulated human COX-2 promoter expression, and apoptosis due to N-retinylidene-N-retinylethanolamine (A2E). Overall, NPD1 protected both nerve and retinal pigment epithelial cells from cellular apoptosis and damage due to oxidative stress.
    Type: Application
    Filed: August 5, 2004
    Publication date: April 7, 2005
    Inventors: Nicolas Bazan, Charles Serhan, Victor Marcheselli, Pranab Mukherjee, Sebastian Barreiro, Walter Lukiw, Song Hong, Karsten Gronert, Alberto Musto