Patents by Inventor Prasad Sarma

Prasad Sarma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DISSOCIATION AND RECOMBINATION CATALYST LAYERS FOR REVERSE AND FORWARD-BIAS BIPOLAR MEMBRANES
    Publication number: 20230264148
    Abstract: A bipolar membrane comprising a first member comprising at least one anion exchange material; a second member comprising at least one cation exchange material, wherein the first member and the second member together form an interface junction; and disposed within the interface junction a solitary layer comprising a composite water dissociation catalyst or a composite water recombination catalyst.
    Type: Application
    Filed: February 22, 2023
    Publication date: August 24, 2023
    Applicant: University of Oregon
    Inventors: Shannon Boettcher, Lihaokun Chen, James Mitchell, Sayantan Sasmal, Nicole Sagui, Prasad Sarma
  • Process for the manufacture of rosuvastatin calcium using crystalline rosuvastatin ethyl ester
    Patent number: 8846915
    Abstract: The present invention relates to an improved process to prepare Rosuvastatin calcium of Formula (I), with good quality. Further, the present invention also relates to a crystalline polymorphic form of Rosuvastatin ethyl ester.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: September 30, 2014
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Ganagadnar Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for the preparation of Dutasteride
    Patent number: 8563728
    Abstract: The present invention provides an improved process for the preparation of Dutasteride (I) which comprises: (i) reacting 4-aza-5?-androst-1-en-3-one-17?-carboxylic acid (VII), Formula VII with sulfonic acid anhydride (RSO2)2O in presence of base to produce an intermediate compound of Formula (XIII), wherein R represents C1-6 alkyl, C1-6 halo alkyl, C6-10 aryl, halo aryl; (ii) condensing compound of Formula (XIII) with 2,5-bis(trifluoromethyl)aniline (III), Formula (III) in the presence or absence of a base to produce Dutasteride (I).
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: October 22, 2013
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Balanarasimha Reddy Gona, Naresh Akkina, Rani Ananta, Islam Aminul, Sivakumaran Meenakshisunderam
  • Process for preparing pyrimidine propenaldehyde
    Patent number: 8394956
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of formula (I), which is an useful intermediate in the preparation of Rosuvastatin.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: March 12, 2013
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhara Bhima Shankar Nangi, Rani Ananta, Sivakumaran Meenakshisunderam
  • Process for preparing rosuvastatin calcium
    Patent number: 8318933
    Abstract: The present invention relates to an improved process for preparing Rosuvastatin calcium of Formula I.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: November 27, 2012
    Assignee: Aurobindo Pharma Ltd
    Inventors: Sambhu Prasad Sarma Mallela, Narayan K. A. S. S. Garimella, Sukumar Nandi, Sunil Kumar Buridipad, Gangadhar Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for preparing rosuvastatin calcium
    Patent number: 8212034
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-iso-propyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of Formula I which is an intermediate useful in the preparation of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid]calcium salt of Formula II.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • Process for preparation of rosuvastatin calcium field of the invention
    Patent number: 8212035
    Abstract: The present invention relates to an improved process for preparing (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium of Formula (I).
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nandi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE PREPARATION OF DUTASTERIDE
    Publication number: 20120157683
    Abstract: The present invention provides an improved process for the preparation of Dutasteride (I) which comprises: (i) reacting 4-aza-5?-androst-1-en-3-one-17?-carboxylic acid (VII), Formula VII with sulfonic acid anhydride (RSO2)2O in presence of base to produce an intermediate compound of Formula (XIII), wherein R represents C1-6 alkyl, C1-6 halo alkyl, C6-10 aryl, halo aryl; (ii) condensing compound of Formula (XIII) with 2,5-bis(trifluoromethyl)aniline (III), Formula (III) in the presence or absence of a base to produce Dutasteride (I).
    Type: Application
    Filed: July 7, 2010
    Publication date: June 21, 2012
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Balanarasimha Reddy Gona, Naresh Akkina, Rami Ananta, Islam Aminul, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER
    Publication number: 20120149905
    Abstract: The present invention relates to an improved process to prepare Rosuvastatin calcium of Formula (I), with good quality. Further, the present invention also relates to a crystalline polymorphic form of Rosuvastatin ethyl ester.
    Type: Application
    Filed: August 17, 2009
    Publication date: June 14, 2012
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhara Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for preparing pyrimidine propenaldehyde
    Publication number: 20110178296
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of formula (I), which is an useful intermediate in the preparation of Rosuvastatin.
    Type: Application
    Filed: September 23, 2009
    Publication date: July 21, 2011
    Inventors: Sambhu Prasad Sarma Mallela, Sakumar Nandi, Gangadhara Bhima Shankar Nangi, Rani Ananta, Sivakumaran Meenakshiunderam
  • PROCESS FOR PREPARING ROSUVASTATIN CALCIUM
    Publication number: 20100048899
    Abstract: The present invention relates to an improved process for preparing Rosuvastatin calcium of Formula I.
    Type: Application
    Filed: October 29, 2007
    Publication date: February 25, 2010
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Narayan K.A.S.S. Garimella, Sukumar Nandi, Sunil Kumar Buridipad, Gangadhar Bhima Shankar Nangi, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARING ROSUVASTATIN CALCIUM
    Publication number: 20100029940
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of Formula I which is an intermediate useful in the preparation of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methyl-sulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid] calcium salt of Formula II
    Type: Application
    Filed: December 11, 2007
    Publication date: February 4, 2010
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARATION OF ROSUVASTATIN CALCIUM FIELD OF THE INVENTION
    Publication number: 20090312547
    Abstract: The present invention relates to an improved process for preparing (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium of Formula (I).
    Type: Application
    Filed: February 4, 2008
    Publication date: December 17, 2009
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam