Patents by Inventor Prasanna Malaviya
Prasanna Malaviya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8025896Abstract: A method of making an implantable scaffold for repairing damaged or diseased tissue includes the step of suspending pieces of an extracellular matrix material in a liquid. The extracellular matrix material and the liquid are formed into a mass. The liquid is subsequently driven off so as to form interstices in the mass. Porous implantable scaffolds fabricated by such a method are also disclosed.Type: GrantFiled: July 15, 2002Date of Patent: September 27, 2011Assignee: DePuy Products, Inc.Inventors: Prasanna Malaviya, Herbert E. Schwartz, Pamela L. Plouhar, Mark J. Pelo
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Patent number: 8012205Abstract: A cartilage repair device comprises a scaffold, for example a naturally occurring extracellular matrix material, and a biological lubricant. The biological lubricant is applied to the naturally occurring extracellular matrix material.Type: GrantFiled: July 15, 2002Date of Patent: September 6, 2011Assignee: DePuy Products, Inc.Inventors: Pamela Lynn Plouhar, Prasanna Malaviya, Herbert Eugene Schwartz
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Publication number: 20110196403Abstract: In various embodiments, a surgical instrument for operation in an aqueous environment is provided. In at least one embodiment, the surgical instrument may include a hollow sheath, a blade disposed at least partially within the hollow sheath and extending through an opening in the sheath, and at least one ultrasonic transducer operably coupled to the blade. The blade may include a polygonal cross-sectional shape and the tip may project away from the sheath's longitudinal axis. In another embodiment, the surgical instrument may include a blade with suction disposed therethrough and at least one ultrasonic transducer operably coupled to the blade. The blade may include a cutting edge that is positioned over a blade opening. Also, the cutting edge may project away from the blade's longitudinal axis.Type: ApplicationFiled: February 11, 2010Publication date: August 11, 2011Applicant: Ethicon Endo-Surgery, Inc.Inventors: Galen C. Robertson, Matthew C. Miller, Prasanna Malaviya
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Publication number: 20110196287Abstract: In one general aspect, various embodiments are directed to methods for treating tissue within an aqueous environment. Various methods may include introducing a cutting implement of a surgical instrument into the aqueous environment. The cutting implement may have at least one cutting surface thereon and at least one ultrasonic portion thereon and be selectively rotatable within a hollow sheath. The methods may include rotating or rotatably oscillating the cutting implement within the hollow sheath for tissue cutting purposes. The cutting implement may also be retained in a position wherein the ultrasonic portion of the cutting implement may be applied to tissue and then have ultrasonic motion applied thereto.Type: ApplicationFiled: February 11, 2010Publication date: August 11, 2011Applicant: Ethicon Endo-Surgery, Inc.Inventors: Galen C. Robertson, Richard W. Timm, Daniel J. Mumaw, Foster B. Stulen, Gregory W. Johnson, Jerome R. Morgan, Kevin L. Houser, Kristi M. Bodin, Mark A. Neurohr, Prasanna Malaviya, Reginald D. Fortson, Sean P. Conlon, William S. Joachim, JR., William D. Dannaher, Eitan T. Wiener
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Publication number: 20110196286Abstract: In one general aspect, various embodiments are directed to an ultrasonic surgical instrument that comprises a handpiece housing that rotatably supports an ultrasonic transducer assembly therein that may be selectively rotated by various motor configurations. Various slip ring arrangements are disclosed for supplying ultrasonic electrical signals and motor drive signals from a control system. Various forms of blade and cutting implements are disclosed for attachment to the ultrasonic transducer assembly such that such implements may be selectively rotatable within a hollow outer sheath. Vacuum may be applied to the cutting implement or through the outer sheath to draw tissue through an opening in the sheath and into contact with the cutting implement.Type: ApplicationFiled: February 11, 2010Publication date: August 11, 2011Applicant: Ethicon Endo-Surgery, Inc.Inventors: Galen C. Robertson, Richard W. Timm, Daniel J. Mumaw, Foster B. Stulen, Gregory W. Johnson, Jerome R. Morgan, Kevin L. Houser, Kristi M. Bodin, Mark A. Neurohr, Prasanna Malaviya, Reginald D. Fortson, Sean P. Conlon, William S. Joachim, JR., William D. Dannaher, Eitan T. Wiener
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Publication number: 20110152759Abstract: Biomarkers are collected and used to determine biological propensities of a patient, to determine the efficacy of medical devices, to select and administer therapeutic agents, to select medical devices, to make adjustments to medical devices, and/or to adjust surgical techniques. An apparatus includes a port to draw a biological fluid (e.g., a mist) from a surgical site. The apparatus includes a sensor having a cantilevered beam. The beam includes substances selected to attract certain biomarkers as the fluid is communicated across the beam. The same apparatus or another apparatus is used to administer a therapeutic agent based at least in part on collected biomarker data. The therapeutic agent delivery apparatus may include a device that is also used to create a wound at a surgical site. For instance, a harmonic surgical instrument may be used to both collect biomarkers and administer a therapeutic agent (e.g., gene therapy using sonoporation).Type: ApplicationFiled: December 17, 2010Publication date: June 23, 2011Inventors: Jeffrey W. Clymer, Prasanna Malaviya, Donna L. Korvick, Kevin L. Houser, Cory G. Kimball, Foster B. Stulen, Frederick E. Shelton, IV, Chester O. Baxter, III, Taylor W. Aronhalt
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Patent number: 7914808Abstract: Methods of making a hybrid biologic/synthetic scaffold for repairing damaged or diseased tissue are provided. The methods include the step of suspending pieces of an extracellular matrix material in a liquid to form a slurry, and coating a synthetic mat with the slurry, or mixing or layering the slurry with a synthetic polymer solution. The liquid is subsequently driven off so as to form a foam. Porous implantable scaffolds fabricated by such a method are also disclosed.Type: GrantFiled: July 15, 2002Date of Patent: March 29, 2011Assignee: DePuy Products, Inc.Inventors: Prasanna Malaviya, Mora C. Melican, Alireza Rezania, Iksoo Chun
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Patent number: 7871440Abstract: Unitary surgical devices (10) are disclosed. One group of the illustrated devices has a pair of biocompatible, bioresorbable anchors (16,18) connected to fixed lengths suture. The anchors (16,18) and fixed length of suture are connected to each other prior to surgery. Another group of unitary surgical devices has a pair of fixating mechanisms (15,17) connected to a base (21) prior to surgery. The second group of illustrated devices generally includes extracellular matrix material either as part of the base (21) or supported on the base (21). The extracellular matrix material serves as tissue regenerating material. In the second group of unitary surgical devices, the fixating mechanisms illustrated generally comprise suture, anchors or pre-formed holes in the base. All of the illustrated unitary surgical devices are useful in repairing a damaged meniscus. The first group of unitary surgical devices can be used to approximate inner surfaces of a tear in the meniscus.Type: GrantFiled: December 11, 2006Date of Patent: January 18, 2011Assignee: Depuy Products, Inc.Inventors: Herbert E. Schwartz, Prasanna Malaviya, Amit K. Singla, Pamela Lynn Plouhar, Mark Joseph Pelo
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Patent number: 7819918Abstract: An implantable tissue repair device has a cover and tissue regeneration material. The cover includes a top panel and a bottom panel joined together along a leading edge. The tissue regeneration material is positioned between the top and bottom panels. The cover includes a continuous sheet of biocompatible material extending across the edge and into the top panel and bottom panel. The cover is thicker along the leading edge than at least a portion of the top panel and thicker than at least a portion of the bottom panel. At least a portion of one of the panels covering the tissue regeneration material is thicker than a portion of the other panel covering the tissue regeneration material. A method of making the device is also disclosed.Type: GrantFiled: December 29, 2003Date of Patent: October 26, 2010Assignee: Depuy Products, Inc.Inventors: Prasanna Malaviya, Herbert E. Schwartz, Anthony D. Zannis, Terrence David Whalen, Philip Joseph Jenks
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Patent number: 7799089Abstract: Bioprosthetic devices for soft tissue attachment, reinforcement, or construction are provided. The devices comprise a sheet of naturally occurring extracellular matrix and a sheet of synthetic mesh coupled to the naturally occurring extracellular matrix portion.Type: GrantFiled: October 10, 2006Date of Patent: September 21, 2010Assignee: DePuy Orthopaedics, Inc.Inventors: Pamela Lynn Plouhar, Prasanna Malaviya, Joe W. Ferguson, Mora Carolynne Melican
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Patent number: 7785332Abstract: A cannula has a flange and a body with slots extending through the entire flange and into the body. The cannula may also have a longitudinal slot extending its entire length. An obturator used with the cannula may also have a longitudinal slot extending along its length. A surgical method using these instruments includes separating lengths of suture and managing the suture by placing lengths of suture in the slots in the cannula. The cannula and obturator may be used after suture is already in place by placing the suture in the longitudinal slots and then introducing the cannula and obturator to the tissue defect site. The cannula may also be used to deliver a therapeutic implant to the tissue defect site. The instruments and method may be used in mensical surgery.Type: GrantFiled: October 28, 2005Date of Patent: August 31, 2010Assignee: Depuy Products, Inc.Inventors: Anthony D. Zannis, Prasanna Malaviya, Keith M. McGrath, Herbert E. Schwartz
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Publication number: 20100189759Abstract: A method is provided for sequential decellularization of an isolated tissue using solubilizing solutions comprising at least one oxidizing agent that removes all cellular and nuclear materials from the tissue while substantially maintaining the biological and, mechanical properties, and the biochemical properties of the resulting extracellular matrix.Type: ApplicationFiled: April 2, 2010Publication date: July 29, 2010Applicant: DEPUY SPINE, INC.Inventors: Rangamani Padmini, Janine Orban, Prasanna Malaviya
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Patent number: 7763459Abstract: A method is provided for sequential decellularization of an isolated tissue using solubilizing solutions comprising at least one oxidizing agent that removes all cellular and nuclear materials from the tissue while substantially maintaining the biological and, mechanical properties, and the biochemical properties of the resulting extracellular matrix.Type: GrantFiled: September 30, 2004Date of Patent: July 27, 2010Assignee: DePuy Spine, Inc.Inventors: Rangamani Padmini, Janine Orban, Prasanna Malaviya
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Patent number: 7569233Abstract: A bioprosthetic device is provided for soft tissue attachment, reinforcement, and or reconstruction. The device comprises a naturally occurring extracellular matrix portion and a synthetic portion.Type: GrantFiled: April 20, 2005Date of Patent: August 4, 2009Assignee: DePuy Products, Inc.Inventors: Prasanna Malaviya, Janine M. Orban, Philip J. Jenks, Terrence D. Whalen
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Patent number: 7559941Abstract: A surgical instrument has a main shaft underlying a slide member. The slide member is movable in a proximal-distal direction. The distal end of the slide member has an open position and a closed position. The closed position is spaced from the open position in the proximal-distal direction. There is a gap between the distal end of the slide member and the distal end of the main shaft when the instrument is in the open position. The gap is smaller when the instrument is in the closed position. An implant can be received in the gap and delivered to a damaged tissue site using the instrument. An implant protector can be used when delivering the implant with the instrument. A pivotable implant cover can be used to protect the implant instead of the slide member.Type: GrantFiled: December 19, 2003Date of Patent: July 14, 2009Assignee: Depuy Products, Inc.Inventors: Anthony D. Zannis, John W. Kemppainen, Andrew M. Jacobs, Carolyn K. Day, Rhonda B. Clarke, Herbert E. Schwartz, Prasanna Malaviya, Danny E. McAdams
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Patent number: 7473259Abstract: A surgical instrument stabilizes an implant as the implant is secured to native tissue at a damaged tissue site such as in an intra-articular space. The instrument has a proximal end portion, a distal end portion and an intermediate portion. The distal end portion has a template for guiding an attachment mechanism into the implant and the adjacent native tissue. The distal end portion can also have barbs to engage the implant to enhance stabilization of the implant. Several instruments can be provided in a surgical kit with different lengths and shapes of distal end portions. A surgical kit could also contain modular distal end portions of varying sizes and shapes. A surgical method utilizing the stabilizing instrument is also disclosed.Type: GrantFiled: June 30, 2003Date of Patent: January 6, 2009Assignee: Depuy Products, Inc.Inventors: Andrew M. Jacobs, Carolyn K. Day, Rhonda B. Clarke, Herbert E. Schwartz, John W. Kemppainen, Prasanna Malaviya, Anthony D. Zannis
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Publication number: 20080294193Abstract: Unitary surgical devices (10) are disclosed. One group of the illustrated devices has a pair of biocompatible, bioresorbable anchors (16,18) connected to fixed lengths suture. The anchors (16,18) and fixed length of suture are connected to each other prior to surgery. Another group of unitary surgical devices has a pair of fixating mechanisms (15,17) connected to a base (21) prior to surgery. The second group of illustrated devices generally includes extracellular matrix material either as part of the base (21) or supported on the base (21). The extracellular matrix material serves as tissue regenerating material. In the second group of unitary surgical devices, the fixating mechanisms illustrated generally comprise suture, anchors or pre-formed holes in the base. All of the illustrated unitary surgical devices are useful in repairing a damaged meniscus. The first group of unitary surgical devices can be used to approximate inner surfaces of a tear in the meniscus.Type: ApplicationFiled: October 30, 2007Publication date: November 27, 2008Inventors: HERBERT E. SCHWARTZ, Prasanna Malaviya, Amit K. Singla, Pamela Lynn Plouhar, Mark Joseph Pelo
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Publication number: 20080234708Abstract: A surgical instrument that may include a housing, a transducer engaged with the housing which can produce vibrations, and an end-effector engaged with the transducer. The surgical instrument can further include an adjustable sheath extending from the housing where the sheath is movable relative to the distal tip of the end-effector and where the distance between the distal tip of the sheath and the distal tip of the end-effector can be set such that the sheath can act as a depth stop. The sheath can be adjusted such that, when the distal tip of the sheath contacts the tissue or bone being incised, the surgeon can determine that the appropriate depth of the incision has been reached. In other embodiments, the end-effector can be moved with respect to the sheath in order to adjust the distance between the distal tip of the end-effector and the distal tip of the sheath.Type: ApplicationFiled: March 22, 2007Publication date: September 25, 2008Inventors: Kevin L. Houser, Andrew M. Zwolinski, Tracy D. Lopes, Prasanna Malaviya, Daniel W. Price, Louis T. DeLuca
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Publication number: 20080167716Abstract: An orthopaedic device for repairing and regenerating cartilage includes a plug configured to be positioned in a hole formed in the cartilage and an anchor configured to support the plug. One or both of the plug and the anchor may be formed from naturally occurring extracellular matrix such as small intestine submucosa. A method for repairing and regenerating cartilage is also disclosed.Type: ApplicationFiled: March 21, 2008Publication date: July 10, 2008Inventors: Hebert E. Schwartz, Prasanna Malaviya, Mark J. Pelo, Pamela L. Plouhar
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Publication number: 20080140094Abstract: Unitary surgical devices (10) are disclosed. One group of the illustrated devices has a pair of biocompatible, bioresorbable anchors (16,18) connected to fixed lengths suture. The anchors (16,18) and fixed length of suture are connected to each other prior to surgery. Another group of unitary surgical devices has a pair of fixating mechanisms (15,17) connected to a base (21) prior to surgery. The second group of illustrated devices generally includes extracellular matrix material either as part of the base (21) or supported on the base (21). The extracellular matrix material serves as tissue regenerating material. In the second group of unitary surgical devices, the fixating mechanisms illustrated generally comprise suture, anchors or pre-formed holes in the base. All of the illustrated unitary surgical devices are useful in repairing a damaged meniscus. The first group of unitary surgical devices can be used to approximate inner surfaces of a tear in the meniscus.Type: ApplicationFiled: December 11, 2006Publication date: June 12, 2008Inventors: HERBERT E. SCHWARTZ, PRASANNA MALAVIYA, AMIT K. SINGLA, PAMELA LYNN PLOUHAR, MARK JOSEPH PELO