Abstract: A first vehicle-to-everything (V2X) device may operate in compliance with a first regional standard governing V2X Basic Safety Messages (BSMs) for a first geographical region, and a second V2X device may operate in compliance with a second regional standard governing V2X BSMs for a second geographical region. When the first V2X device is operating within the second geographical region, it may generate “global BSMs” in accordance with a multi-regional standard governing V2X BSMs. The second V2X device may process global BSMs generated by the first V2X device and may respond by generating its own global BSMs.

Abstract: A system and method for building a driver are disclosed. In one embodiment, the system includes one or more processors and a memory storing instructions that, when executed by the processor, cause the system to: obtain an interface description; obtain at least one mapping rule; operate a flow controller that controls a flow of operations, the operations using one or more of the interface description and the at least one mapping rule; obtain a protocol adapter; and implement access to a data source based on the operation of the flow controller using the obtained protocol adapter.

Abstract: A system and method for building a driver are disclosed. In one embodiment, the system includes one or more processors and a memory storing instructions that, when executed by the processor, cause the system to: obtain an interface description; obtain at least one mapping rule; operate a flow controller that controls a flow of operations, the operations using one or more of the interface description and the at least one mapping rule; obtain a protocol adapter; and implement access to a data source based on the operation of the flow controller using the obtained protocol adapter.

Abstract: The present invention provides single chain antibody-directed polymeric prodrugs containing multifunctional linkers. Methods of making the polymeric delivery systems and methods of treating mammals using the same are also disclosed.

Abstract: The present invention is directed to nucleic acids delivery systems and methods of modulating an expression of a target gene using the same. In particular, the invention relates to nucleic acids conjugates containing an endosomal release-promoting moiety. The nucleic acids conjugates further contain a nuclear localization signal moiety, and/or a cell targeting moiety.

Abstract: The present invention provides polymeric prodrugs including an intracellular releasable disulfide linker for the delivery of oligonucleotides. Methods of making the compounds as well as methods of delivering nucleic acids to tumor cells in a mammal using the same are also provided.

Abstract: The present invention provides polymeric linkers containing pyridyl disulfide moieties. Methods of making the polymeric linkers and methods of making conjugates using the same are also disclosed.

Abstract: The present invention provides polymeric linkers containing branching moieties. Methods of making the polymeric linkers and methods of making conjugates using the same are also disclosed.

Abstract: The present invention provides polymeric conjugates containing positively charged moieties. Methods of making the polymeric delivery systems and methods of treating mammals using the same are also disclosed.