Patents by Inventor Prasenjit K. Mukherjee

Prasenjit K. Mukherjee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRMT5 INHIBITORS AND USES THEREOF
    Publication number: 20240376110
    Abstract: The present disclosure relates generally to compounds that inhibit PRMT5. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting PRMT5. The disclosure further relates to the use of the compounds for the treatment of a disease or condition associated with chromosome 9p21 deletion, MTAP null, or any other MTAP deficiency. The disclosure further relates to the use of the compounds for the treatment of cancers.
    Type: Application
    Filed: May 14, 2024
    Publication date: November 14, 2024
    Inventors: Megan K. Armstrong, Elbert Chin, Chienhung Chou, Laurent P. Debien, Yifan Deng, Joshua D. Farr, Pancham Lal Gupta, Chao-I Hung, Benjamin J. June, Prasenjit K. Mukherjee, Shaina V. Nguyen, Gregory T. Notte, Daniel Roa, Adam J. Schrier, Katie A. Spence, Zheng-Yu Yang
  • INTERLEUKIN-2-Fc FUSION PROTEINS AND METHODS OF USE
    Publication number: 20240269235
    Abstract: Provided are serum half-life extended-IL-2 variant (IL-2v) heterodimers having reduced binding to the IL2R? (CD25) subunit. In particular, Fc-IL-2v heterodimers are provided and methods for making and using, e.g. for enhancing an immune response, e.g. in the prevention and treatment of viral infections and cancer.
    Type: Application
    Filed: December 14, 2023
    Publication date: August 15, 2024
    Inventors: Manuel Baca, Sarah A. Gilmore, Magdeleine S. Hung, Hassan Javanbakht, Manu Kanwar, Shahzada Khan, Prasenjit K. Mukherjee, Mark R. Nagel, Giuseppe Papalia, Danny W. Tam, Majlinda K. Thomas
  • PRMT5 INHIBITORS AND USES THEREOF
    Publication number: 20240254118
    Abstract: The present disclosure relates generally to compounds that inhibit PRMT5. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting PRMT5. The disclosure further relates to the use of the compounds for the treatment of a disease or condition associated with chromosome 9p21 deletion or MTAP null. The disclosure further relates to the use of the compounds for the treatment of cancers.
    Type: Application
    Filed: December 20, 2023
    Publication date: August 1, 2024
    Inventors: Megan K. Armstrong, Elbert Chin, Chienhung Chou, Laurent P. Debien, Joshua D. Farr, Pancham Lal Gupta, Chao-I Hung, Michael L. Mitchell, Prasenjit K. Mukherjee, Shaina V. Nguyen, Gregory T. Notte, Daniel Roa, Adam J. Schrier, Zheng-Yu Yang
  • Interleukin-2 variant proteins fused to human IgG4 Fc and uses thereof
    Patent number: 11896648
    Abstract: Provided are serum half-life extended-IL-2 variant (IL-2v) heterodimers having reduced binding to the IL2R? (CD25) subunit. In particular, Fc-IL-2v heterodimers are provided and methods for making and using, e.g. for enhancing an immune response, e.g. in the prevention and treatment of viral infections and cancer.
    Type: Grant
    Filed: October 20, 2021
    Date of Patent: February 13, 2024
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Manuel Baca, Sarah A. Gilmore, Hassan Javanbakht, Prasenjit K. Mukherjee
  • INTERLEUKIN-2-Fc FUSION PROTEINS AND METHODS OF USE
    Publication number: 20220125884
    Abstract: Provided are serum half-life extended-IL-2 variant (IL-2v) heterodimers having reduced binding to the IL2R? (CD25) subunit. In particular, Fc-IL-2v heterodimers are provided and methods for making and using, e.g. for enhancing an immune response, e.g. in the prevention and treatment of viral infections and cancer.
    Type: Application
    Filed: October 20, 2021
    Publication date: April 28, 2022
    Inventors: Manuel Baca, Sarah A. Gilmore, Magdeleine S. Hung, Hassan Javanbakht, Manu Kanwar, Shahzada Khan, Prasenjit K. Mukherjee, Mark R. Nagel, Giuseppe Papalia, Danny W. Tam, Majlinda K. Thomas