Patents by Inventor Prashant N. Kumta
Prashant N. Kumta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11898055Abstract: The invention relates to polyelectrolyte multilayer coatings and, methods for their preparation and application to substrates to enhance the bioactivity and corrosion protection of the substrates' surface. The invention is particularly suitable for coating substrates employed for medical applications, such as but not limited to medical implant devices for drug and/or biologics delivery in a patient. The substrate has a positive or negative charge. The polyelectrolyte multilayer coatings include at least a first polymer layer and a second polymer layer. The first polymer and second polymer have opposite charges. Each of the polymer layers is individually applied using a layer-by-layer such that an alternating charge multilayer coating is formed.Type: GrantFiled: October 6, 2021Date of Patent: February 13, 2024Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Sangeetha Kunjukunju, Nicole J. Ostrowski, Abhijit Roy, Boeun Lee, Madhumati Ramanathan
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Patent number: 11896735Abstract: The invention includes compositions including magnesium-lithium alloys containing various alloying elements for medical implant devices. The devices are constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also includes methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, including orthopedic, dental, craniofacial and cardiovascular surgery.Type: GrantFiled: July 21, 2021Date of Patent: February 13, 2024Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Jingyao Wu, Oleg Velikokhatnyi
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Publication number: 20230381382Abstract: The invention relates to biodegradable, magnesium alloys, compositions and composites, methods for their preparation and applications for their use as implantable medical devices in load-bearing conditions. The magnesium alloys are composed of alloying elements selected from yttrium, calcium, zirconium, zinc, and strontium, with the remainder being magnesium and impurities arising due to production, and preparation of the alloy by melting together the elements and casting the resulting melted mixture. In certain embodiments, the methods of preparation include solution treatment and hot extrusion.Type: ApplicationFiled: June 1, 2023Publication date: November 30, 2023Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: PRASHANT N. KUMTA, ABHIJIT ROY, DA-TREN CHOU, DAEHO HONG, VIJAY S. GORANTLA
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Publication number: 20230313346Abstract: The invention relates to biodegradable, metal alloys, methods for their preparation and applications for their use. The alloys include magnesium and other components, such as, yttrium, calcium, zirconium, and zinc. These elements are alloyed together in specific combinations and amounts in order to achieve an alloy having desired properties and characteristics. In certain embodiments, strontium or cerium may be included as an additive. The resulting alloys are particularly suitable for forming various medical devices for implantation into the body of a patient.Type: ApplicationFiled: January 20, 2023Publication date: October 5, 2023Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventor: PRASHANT N. KUMTA
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Patent number: 11732334Abstract: The invention relates to biodegradable, metal alloys, methods for their preparation and applications for their use. The alloys include magnesium and other components, such as, yttrium, calcium, zirconium, and zinc. These elements are alloyed together in specific combinations and amounts in order to achieve an alloy having desired properties and characteristics. In certain embodiments, strontium or cerium may be included as an additive. The resulting alloys are particularly suitable for forming various medical devices for implantation into the body of a patient.Type: GrantFiled: April 12, 2018Date of Patent: August 22, 2023Assignee: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventor: Prashant N. Kumta
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Patent number: 11728543Abstract: The invention relates to lithium ion batteries and, more particularly, to lithium ion conducting composite polymer electrolyte separators. The separators include a nanofiber mat composed of electrospun nanofibers. The nanofibers include a polymer having one or more polar halogen groups, a lithium-containing solid or liquid electrolyte and nanoparticle filler. The polymer, electrolyte and filler are combined to form a solution that is subjected to the electro-spinning process to produce electrospun nanofibers in the form of the mat.Type: GrantFiled: July 9, 2018Date of Patent: August 15, 2023Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Bharat Gattu, Moni Kanchan Datta, Oleg Velikokhatnyi, Pavithra Murugavel Shanthi, Prashanth Jampani Hanumantha
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Patent number: 11696976Abstract: The invention relates to biodegradable, magnesium alloys, compositions and composites, methods for their preparation and applications for their use as implantable medical devices in load-bearing conditions. The magnesium alloys are composed of alloying elements selected from yttrium, calcium, zirconium, zinc, and strontium, with the remainder being magnesium and impurities due to production, and are prepared by melting together the elements and casting the resulting melted mixture. In certain embodiments, the methods of preparation include solution treatment and hot extrusion.Type: GrantFiled: August 22, 2016Date of Patent: July 11, 2023Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Abhijit Roy, Da-Tren Chou, Daeho Hong, Vijay S. Gorantla
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Publication number: 20230211053Abstract: The invention relates to biodegradable iron alloy-containing compositions for use in preparing medical devices. In addition, biodegradable crystalline and amorphous compositions of the invention exhibit properties that make them suitable for use as medical devices for implantation into a body of a patient. The compositions include elemental iron and one or more elements selected from manganese, magnesium, zirconium, zinc and calcium. The compositions can be prepared using a high energy milling technique. The resulting compositions and the devices formed therefrom are useful in various surgical procedures, such as but not limited to orthopedic, craniofacial and cardiovascular.Type: ApplicationFiled: February 24, 2023Publication date: July 6, 2023Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: PRASHANT N. KUMTA, SUNG JAE CHUNG, PARTHA SAHA, OLEG VELIKOKHATNYI, MONI KANCHAN DATTA, DAE HO HONG, DA-TREN CHOU
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Patent number: 11638645Abstract: The invention relates generally to generation of biomimetic scaffolds for bone tissue engineering and, more particularly, to multi-level lamellar structures having rotated or alternated plywood designs to mimic natural bone tissue. The invention also includes methods of preparing and applying the scaffolds to treat bone tissue defects. The biomimetic scaffold includes a lamellar structure having multiple lamellae and each lamella has a plurality of layers stacked parallel to one another. The lamellae and/or the plurality of layers is rotated at varying angles based on the design parameters from specific tissue structural imaging data of natural bone tissue, to achieve an overall trend in orientation to mimic the rotated lamellar plywood structure of the naturally occurring bone tissue.Type: GrantFiled: September 22, 2020Date of Patent: May 2, 2023Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Gary Yu, Abhijit Roy
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Publication number: 20230073429Abstract: The invention relates to a device and method for preparing a structure or object using an additive manufacturing process referred to as sequential cold spray laser sintering. The method includes depositing by cold spraying a plurality of sequential layers of material onto a substrate/build plate or particles of materials onto a compacted powder bed of material and employing an energy source to sinter or melt each of the plurality of sequential layers or powders to produce sequential sintered layers, wherein the number of additional layers is determined based on those needed to produce the final structure.Type: ApplicationFiled: February 26, 2021Publication date: March 9, 2023Applicants: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, CONCURRENT TECHNOLOGIES CORPORATIONInventors: Prashant N. KUMTA, Abhijit ROY, Howard Arthur KUHN, Matthew CRIADO, John Michael OHODNICKI, Brock T. GOLESICH, Juan J. VALENCIA, Michael John POLLOCK, Michael L. TIMS
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Patent number: 11594753Abstract: The invention relates to Chevrel-phase materials and methods of preparing these materials utilizing a precursor approach. The Chevrel-phase materials are useful in assembling electrodes, e.g., cathodes, for use in electrochemical cells, such as rechargeable batteries. The Chevrel-phase materials have a general formula of Mo6Z8 (Z=sulfur) or Mo6Z18-yZ2y (Z1=sulfur; Z2=selenium), and partially cuprated Cu1Mo6S8 as well as partially de-cuprated Cu1-xMgxMo6S8 and the precursors have a general formula of MxMo6Z8 or MxMo6Z18-yZ2y, M=Cu. The cathode containing the Chevrel-phase material in accordance with the invention can be combined with a magnesium-containing anode and an electrolyte.Type: GrantFiled: October 30, 2020Date of Patent: February 28, 2023Assignees: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Partha Saha, Moni Kanchan Datta, Ayyakkannu Manivannan
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Patent number: 11590266Abstract: The invention relates to biodegradable iron alloy-containing compositions for use in preparing medical devices. In addition, biodegradable crystalline and amorphous compositions of the invention exhibit properties that make them suitable for use as medical devices for implantation into a body of a patient. The compositions include elemental iron and one or more elements selected from manganese, magnesium, zirconium, zinc and calcium. The compositions can be prepared using a high energy milling technique. The resulting compositions and the devices formed therefrom are useful in various surgical procedures, such as but not limited to orthopedic, craniofacial and cardiovascular.Type: GrantFiled: September 4, 2019Date of Patent: February 28, 2023Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Sung Jae Chung, Partha Saha, Oleg Velikokhatnyi, Moni Kanchan Datta, Dae Ho Hong, Da-Tren Chou
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Patent number: 11575127Abstract: The invention relates to composite multilayer lithium ion battery anodes that include a porous metal alloy foam, and a lithium ion conductor coating applied to the metal alloy foam. The metal alloy foam can include structurally isomorphous alloys of lithium and, optionally, lithium and magnesium. The lithium ion conductor coating can include ternary lithium silicate, such as, lithium orthosilicate. Lithium ions from the ternary lithium silicate may be deposited within the pores of the metal alloy foam. Optionally, the lithium ion conductor coating may include a dopant. The dopant can include one or more of magnesium, calcium, vanadium, niobium and fluorine, and mixtures and combinations thereof.Type: GrantFiled: July 9, 2018Date of Patent: February 7, 2023Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Bharat Gattu, Moni Kanchan Datta, Oleg Velikokhatnyi, Pavithra Murugavel Shanthi, Prashanth Jampani Hanumantha
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Publication number: 20230006214Abstract: The invention relates to complex framework materials (CFMs) for lithium-sulfur batteries. The CFMs include a CFM host and a coating applied to the CFM host, which includes one or more of an electronic conductor, a lithium ion conductor and a functional catalyst. Further, sulfur is infiltrated into the CFM host creating a sulfur-carbon linkage serving as effective anchors for trapping polysulfides. The systems have been tested in coin cells and pouch cells under lean electrolyte conditions of 3-4 ?l/mg of electrolyte to sulfur ratios showing promise and feasibility.Type: ApplicationFiled: December 14, 2020Publication date: January 5, 2023Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. KUMTA, Prasada Rao TALAKONDA, Moni Kanchan DATTA, Oleg VELIKOKHATNYI, Pavithra Murugavel SHANTHI, Ramalinga KURUBA
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Publication number: 20220376232Abstract: The inventive concepts include at least an electrode architecture including a composite structure that includes engineered carbon nanofibers, a lithium-impervious elastic polymer, a copper collector and a lithium-containing cathode; dendrite-free, lithium metal-plated anode that includes the electrode architecture; and a lithium metal-based lithium ion battery that includes the lithium metal-plated anode, liquid and solid electrolytes and a lithium-free cathode.Type: ApplicationFiled: November 4, 2020Publication date: November 24, 2022Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventor: Prashant N. KUMTA
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Patent number: 11376349Abstract: Biodegradable compositions containing from 10.0 to 95.0 weight percent iron for use in preparing medical devices. These biodegradable compositions exhibit properties that make them suitable for use as medical devices for implantation into a body of a patient. The compositions also include one or more elements selected from manganese, magnesium, zirconium, zinc and calcium. The compositions can be prepared using a high energy milling technique and high energy mechanical alloying followed by compaction and sintering, film deposition techniques, such as, pulsed laser deposition (PLD), as well as melting, casting, homogenization and extrusion methods. The resulting compositions and the medical devices formed therefrom are useful in various surgical procedures, such as but not limited to orthopedic, craniofacial and cardiovascular.Type: GrantFiled: October 3, 2013Date of Patent: July 5, 2022Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Sung Jae Chung, Partha Saha, Oleg Velikokhatnyi, Moni Kanchan Datta, Dae Ho Hong, Da-Tren Chou
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Publication number: 20220041890Abstract: The invention relates to polyelectrolyte multilayer coatings and, methods for their preparation and application to substrates to enhance the bioactivity and corrosion protection of the substrates' surface. The invention is particularly suitable for coating substrates employed for medical applications, such as but not limited to medical implant devices for drug and/or biologics delivery in a patient. The substrate has a positive or negative charge. The polyelectrolyte multilayer coatings include at least a first polymer layer and a second polymer layer. The first polymer and second polymer have opposite charges. Each of the polymer layers is individually applied using a layer-by-layer such that an alternating charge multilayer coating is formed.Type: ApplicationFiled: October 6, 2021Publication date: February 10, 2022Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. KUMTA, Sangeetha KUNJUKUNJU, Nicole J. OSTROWSKI, Abhijit ROY, Boeun LEE, Madhumati RAMANATHAN
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Patent number: 11230775Abstract: The invention provides electro-catalyst compositions for an anode electrode of an acid mediated proton exchange membrane-based water electrolysis system. The compositions include a noble metal component selected from the group consisting of iridium oxide, ruthenium oxide, rhenium oxide and mixtures thereof, and a non-noble metal component selected from the group consisting of tantalum oxide, tin oxide, niobium oxide, titanium oxide, tungsten oxide, molybdenum oxide, yttrium oxide, scandium oxide, cooper oxide, zirconium oxide, nickel oxide and mixtures thereof. Further, the non-noble metal component can include a dopant. The dopant can be at least one element selected from Groups III, V, VI and VII of the Periodic Table. The compositions can be prepared using any solution based methods involving a surfactant approach or a sol gel approach. Further, the compositions are prepared using noble metal and non-noble metal precursors.Type: GrantFiled: September 4, 2019Date of Patent: January 25, 2022Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. Kumta, Karan Sandeep Kadakia, Moni Kanchan Datta, Oleg Velikokhatnyi, Prashanth Jampani Hanumantha
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Publication number: 20210405038Abstract: The invention relates to ex-situ biosensors that impedimetrically detect cardiac biomarkers of interest in a bodily fluid sample derived from a patient. The biosensors include a multi-array of vertically aligned platinum wires having immobilized thereon an aptamer that is selected to specifically and selectively bind to the cardiac markers of interest. The biosensors are contacted with a portion of the bodily fluid sample, and the aptamer binds to the cardiac markers of interest in the bodily fluid sample. As a result, an electrochemical impedance signal is generated and therefore, a change in electrochemical impedance is indicative of the presence of the cardiac markers of interest in the bodily fluid sample. The biosensors are point-of-care, on-demand devices that can be used in a medical environment, as well as in domestic settings.Type: ApplicationFiled: September 10, 2021Publication date: December 30, 2021Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Prashant N. KUMTA, Mitali PATIL
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Publication number: 20210369914Abstract: The invention relates to compositions including magnesium-lithium alloys containing various alloying elements suitable for medical implant devices. The devices may be constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also relates to methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, such as but not limited to, orthopedic, dental, craniofacial and cardiovascular surgery.Type: ApplicationFiled: July 21, 2021Publication date: December 2, 2021Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: PRASHANT N. KUMTA, JINGYAO WU, OLEG VELIKOKHATNYI