Patents by Inventor Prashiela Manga

Prashiela Manga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and agents for treating tyrosinase-positive albinism
    Patent number: 9717722
    Abstract: Methods for treating a subject with tyrosinase-positive albinism; agents and compositions thereof for use in treating tyrosinase-positive albinism; and medicaments for treating tyrosinase-positive albinism are described herein. Such methods; agents and compositions thereof; and medicaments relate to chloroquine or rapamycin or compositions thereof and may further relate to nitisinone used in conjunction with the chloroquine or rapamycin or a composition of either of which.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: August 1, 2017
    Assignee: New York University
    Inventors: Seth J. Orlow, Prashiela Manga
  • METHODS AND AGENTS FOR TREATING TYROSINASE-POSITIVE ALBINISM
    Publication number: 20160120860
    Abstract: Methods for treating a subject with tyrosinase-positive albinism; agents and compositions thereof for use in treating tyrosinase-positive albinism; and medicaments for treating tyrosinase-positive albinism are described herein. Such methods; agents and compositions thereof; and medicaments relate to chloroquine or rapamycin or compositions thereof and may further relate to nitisinone used in conjunction with the chloroquine or rapamycin or a composition of either of which.
    Type: Application
    Filed: May 13, 2014
    Publication date: May 5, 2016
    Applicant: New York University
    Inventors: Seth J. Orlow, Prashiela Manga
  • Methods and compositions that affect melanogenesis
    Patent number: 7604949
    Abstract: The invention provides methods of screening for compounds that affect melanogenesis and the function of P protein in organisms, cells, or cell-free systems. The invention further relates to pharmacologic and cosmetic uses of methods of inhibiting melanogenesis, methods of activating melanogenesis, and compounds and pharmacologic compositions useful for the inhibition or activation of melanogenesis and, therefore, for lightening or darkening the pigmentation of cells and tissue, i.e., skin.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: October 20, 2009
    Assignee: New York University
    Inventors: Seth J. Orlow, Andrea Hall, Prashiela Manga
  • Assay for melanogenesis
    Patent number: 7378232
    Abstract: The invention provides methods for the identification of agents that modify or mimic P protein function. Cells expressing a P protein are generally more sensitive to toxins, and changes in cell viability and/or cell death after exposure of P protein-expressing cells to an agent and a toxin is an indication that such an agent is a modifier of P protein expression. The invention also provides methods for the treatment of melanoma and other cancers.
    Type: Grant
    Filed: May 9, 2003
    Date of Patent: May 27, 2008
    Assignee: New York University
    Inventors: Seth J. Orlow, Prashiela Manga, Liliana Staleva
  • Methods and compositions that affect melanogenesis
    Publication number: 20060188953
    Abstract: The invention provides methods of screening for compounds that affect melanogenesis and the function of P protein in organisms, cells, or cell-free systems. The invention further relates to pharmacologic and cosmetic uses of methods of inhibiting melanogenesis, methods of activating melanogenesis, and compounds and pharmacologic compositions useful for the inhibition or activation of melanogenesis and, therefore, for lightening or darkening the pigmentation of cells and tissue, i.e., skin.
    Type: Application
    Filed: April 20, 2006
    Publication date: August 24, 2006
    Applicant: New York University
    Inventors: Seth Orlow, Andrea Hall, Prashiela Manga
  • Methods and compositions that affect melanogenesis
    Publication number: 20040175767
    Abstract: The invention provides methods of screening for compounds that affect melanogenesis and the function of P protein in organisms, cells, or cell-free systems. The invention further relates to pharmacologic and cosmetic uses of methods of inhibiting melanogenesis, methods of activating melanogenesis, and compounds and pharmacologic compositions useful for the inhibition or activation of melanogenesis and, therefore, for lightening or darkening the pigmentation of cells and tissue, i.e., skin.
    Type: Application
    Filed: January 15, 2004
    Publication date: September 9, 2004
    Applicant: New York University
    Inventors: Seth J. Orlow, Andrea Hall, Prashiela Manga
  • Assay for melanogenesis
    Publication number: 20040038328
    Abstract: The invention provides methods for the identification of agents that modify or mimic P protein function. Cells expressing a P protein are generally more sensitive to toxins, and changes in cell viability and/or cell death after exposure of P protein-expressing cells to an agent and a toxin is an indication that such an agent is a modifier of P protein expression. The invention also provides methods for the treatment of melanoma and other cancers.
    Type: Application
    Filed: May 9, 2003
    Publication date: February 26, 2004
    Applicant: New York University
    Inventors: Seth J. Orlow, Prashiela Manga, Liliana Staleva
  • Methods and compositions that affect melanogenesis
    Publication number: 20020034772
    Abstract: The invention provides methods of screening for compounds that affect melanogenesis and the function of P protein in organisms, cells, or cell-free systems. The invention further relates to pharmacologic and cosmetic uses of methods of inhibiting melanogenesis, methods of activating melanogenesis, and compounds and pharmacologic compositions useful for the inhibition or activation of melanogenesis and, therefore, for lightening or darkening the pigmentation of cells and tissue, i.e., skin.
    Type: Application
    Filed: April 6, 2001
    Publication date: March 21, 2002
    Inventors: Seth J. Orlow, Andrea Hall, Prashiela Manga