Patents by Inventor Prasit Palittapongarnpim

Prasit Palittapongarnpim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antituberculosis compounds, Hirsutellones A, B, and C
    Patent number: 7414069
    Abstract: Three new alkaloids, Hirsutellones A, B, and C, are produced in cultures of fungus such as Hirsutella nivea strain BCC 2594 and Trichoderma sp. strain BCC 7579. The Hirsutellones exhibited potent growth inhibitory activity against Mycobacterium tuberculosis (H37Ra strain) with an MIC value of 0.78 ?g/ml, while showing weak or no cytotoxicity to mammalian cells. Therefore, Hirsutellones and pharmaceutical compositions containing Hirsutellones may be useful for the treatment of tuberculosis. Also described herein are methods of isolating the Hirsutellones.
    Type: Grant
    Filed: November 21, 2005
    Date of Patent: August 19, 2008
    Assignee: National Center for Genetic Engineering & Biotechnology, National Science & Technology Development Agency
    Inventors: Masahiko Isaka, Nigel Leslie Hywel-Jones, Sayanh Somrithipol, Kanyawim Kirtikara, Prasit Palittapongarnpim, Yodhathai Thebtaranonth
  • Novel antituberculosis compounds, Hirsutellones A, B, and C
    Publication number: 20060122252
    Abstract: Three new alkaloids, Hirsutellones A, B, and C, are produced in cultures of fungus such as Hirsutella nivea strain BCC 2594 and Trichoderma sp. strain BCC 7579. The Hirsutellones exhibited potent growth inhibitory activity against Mycobacterium tuberculosis (H37Ra strain) with an MIC value of 0.78 ?g/ml, while showing weak or no cytotoxicity to mammalian cells. Therefore, Hirsutellones and pharmaceutical compositions containing Hirsutellones may be useful for the treatment of tuberculosis. Also described herein are methods of isolating the Hirsutellones.
    Type: Application
    Filed: November 21, 2005
    Publication date: June 8, 2006
    Inventors: Masahiko Isaka, Nigel Hywel-Jones, Sayanh Somrithipol, Kanyawim Kirtikara, Prasit Palittapongarnpim, Yodhathai Thebtaranonth
  • 1'-Acetoxychavicol acetate for tuberculosis treatment
    Publication number: 20020192262
    Abstract: 1′-Acetoxychavicol acetate is a compound not known before to possess anti-tuberculous activity. The above data revealed that the compound was active against the standard H37Ra strain as well as several clinical isolates at the concentration well below the toxic concentration against various mammalian cells. The compound is therefore potentially useful as an therapeutic and preventive agent for tuberculosis as well as an antiseptic agent against the bacteria.
    Type: Application
    Filed: May 23, 2002
    Publication date: December 19, 2002
    Applicant: National Science and Technology Development Agency
    Inventors: Prasit Palittapongarnpim, Chalermpol Kirdmanee, Prasat Kittakoop, Kamolchanok Rukseree