Publication number: 20060183897
Abstract: Biaryl substituted triazole compounds represented by Formula I, II or III, or pharmaceutically acceptable salts thereof, and a process for making such compounds and salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, sodium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, epilepsy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, and bipolar disorder, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds.
Type:
Application
Filed:
March 12, 2004
Publication date:
August 17, 2006
Inventors:
Prasun Chakravarty, Michael Fisher, Brenda Palucki, Min Park, William Parsons, Bishan Zhou, James Carey, Douglas Frantz, Michael Kress, Damian Weaver
Publication number: 20060020006
Abstract: Substituted triazole compounds represented by Formula I, II or III, or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, sodium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, migraine, headache pain, migraine headache, epilepsy, irritable bowel syndrome, diabetic neuropathy, multiple sclerosis, manic depression and bipolar disorder, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds.
Type:
Application
Filed:
November 10, 2004
Publication date:
January 26, 2006
Inventors:
Min Park, Prasun Chakravarty, Bishan Zhou, Edward Gonzalez, Hyun Ok, Brenda Palucki, William Parsons, Rosemary Sisco, Michael Fisher, Louis Zuegner
Publication number: 20050119261
Abstract: Biaryl substituted triazole compounds represented by Formula I, II or III, or pharmaceutically acceptable salts thereof, and a process for making such compounds and salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, sodium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, epilepsy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, and bipolar disorder, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds.
Type:
Application
Filed:
March 12, 2004
Publication date:
June 2, 2005
Inventors:
Prasun Chakravarty, Michael Fisher, Jeffrey Fisher, Brenda Palucki, Min Park, William Parsons, Bishan Zhou, James Carey, Douglas Frantz, Michael Kress, Damian Weaver