Patents by Inventor Pratap Challa

Pratap Challa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250017770
    Abstract: The present disclosure provides devices, systems, and methods relating to the treatment of glaucoma. In particular, the present disclosure is directed to hydrogel implants for use in glaucoma drainage devices to deliver therapeutic agents to a subject's eye and to obviate the need for tying off a drainage tube, thus enhancing therapeutic outcomes.
    Type: Application
    Filed: July 12, 2024
    Publication date: January 16, 2025
    Inventors: Rami Gabriel, Pratap Challa
  • Patent number: 8642644
    Abstract: The present invention relates generally to ophthamological drugs. More specifically, the invention relates to a method of modifying (derivatizing) ophthamological drugs so as to increase their penetration through the cornea. The invention also relates to drugs modified (derivatized) in accordance with the instant method and to the use of same in treating conditions associated with elevated intraocular pressure, particularly, glaucoma.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: February 4, 2014
    Assignee: Duke University
    Inventors: Eric J. Toone, David L. Epstein, Pratap Challa, Phillip W. Snyder, Xin Chen, Mitchell A. deLong
  • Publication number: 20090318542
    Abstract: The present invention relates generally to ophthamological drugs. More specifically, the invention relates to a method of modifying (derivatizing) ophthamological drugs so as to increase their penetration through the cornea. The invention also relates to drugs modified (derivatized) in accordance with the instant method and to the use of same in treating conditions associated with elevated intraocular pressure, particularly, glaucoma.
    Type: Application
    Filed: July 29, 2009
    Publication date: December 24, 2009
    Inventors: Eric J. Toone, David L. Epstein, Pratap Challa, Phillip W. Snyder, Xin Chen, Mitchell A. deLong
  • Publication number: 20070123768
    Abstract: Ophthalmic instruments, systems and methods enable tonometry and pachymetry measurements to be conducted simultaneously. As such, a patient's intraocular pressure (IOP) corrected for corneal thickness may be determined accurately by a single corneal applanation. Preferably, the ophthalmic instruments have a reference surface at a distal end of the instrument, an applanation plate spaced from the reference surface, and a compliant mount for mounting the applanation plate for resilient displacements relative to the reference surface. The instrument most preferably has a housing such that the reference surface is located at a fixed position at one end of the housing, and the applanation plate is mounted to that one end of the housing in coaxial spaced alignment relative to the reference surface by means of the compliant mount.
    Type: Application
    Filed: November 30, 2005
    Publication date: May 31, 2007
    Inventors: Sharon Freedman, Phillip McKinley, Pratap Challa, Leon Herndon, Cynthia Toth, Ronald Overaker, Brian Dodge, Brian Applegate, Joseph Izatt
  • Publication number: 20060135609
    Abstract: The present invention relates generally to ophthamological drugs. More specifically, the inventon relates to a method of modifying (derivatizing) ophthamological drugs so as to increase their penetration through the cornea. The invention also relates to drugs modified (derivatized) in accordance with the instant method and to the use of same in treating conditions associated with elevated intraocular pressure, particularly, glaucoma.
    Type: Application
    Filed: October 21, 2005
    Publication date: June 22, 2006
    Applicant: Duke University
    Inventors: Eric Toone, David Epstein, Pratap Challa, Phillip Snyder, Xin Chen, Mitchell deLong
  • Publication number: 20010053766
    Abstract: The present invention relates, in general, to methods of treating disorders of the eye, and, in particular, to methods of preventing or treating elevated eye pressure and glaucoma. The invention further relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: February 12, 2001
    Publication date: December 20, 2001
    Inventors: Janardan Kumar, Vasanth Rao, David L. Epstein, Pratap Challa