Abstract: A medical device for intradermal injection comprises an injection device 6 and a guiding device 1, which is placed on the skin surface 100 of a subject and comprises a tubular guiding device 2 to guide an axial movement of the injection device 6 toward the skin surface 100. A sleeve-shaped guiding portion 32, 33 tightly matches the profile at the distal end of the injection device 6 to prevent a tilting of the injection device 6 at a foremost distal position of the injection device 6 in the tubular guiding device 2. A positive-fit locking member 24 is provided at a side proximal to the sleeve-shaped guiding portion 32, 33, for locking the foremost distal position of the injection device 6 and coupling the injection device 6 to the guiding device 1. Locking of the injection device generates a sound, indicating that the medical device is ready for injection.

Abstract: A liquid pump dispenser includes a vial adapter connected with a pump dispenser unit including a piston-type dispenser pump. When the vial adapter is coupled to the neck of a medical vial by latching, a piercing mandrel pierces a stopper sealing the vial. A fluid-tight communication between the vial adapter and pump dispenser unit is established by a flexible connecting tube, which helps to compensate mechanical tolerances and any misalignment or between the vial adapter and pump dispenser unit during assembly or use. The liquid pump dispenser can be used in an upside-down orientation of the medical vial without problems such as leakage or dripping at an outlet nozzle, and ensures a precise dosage of the liquid pumped from the medical vial. The vial adapter together with the pump dispenser unit can be pre-assembled and packaged as a unit.

Abstract: A tray for positioning, in a fixed positional relationship, a medical vial 7 together with a vial adapter 4 is disclosed. A tray member 10 includes a vial accommodation cavity 11 and a vial adapter accommodation cavity 12, each comprises retaining members 19, 37a, 37b, 35a, 35b, 36a, 36b configured to position the vial adapter 4 and the vial 7 spaced apart from each other and in axial alignment in an intermediate position. The retaining members 19, 37a, 37b, 35a, 35b, 36a, 36b are further configured to guide a relative axial movement of the vial 7 and vial adapter 4 from the intermediate position to a transfer position while maintaining the axial alignment of the vial 7 with the vial adapter 4. In the transfer position the vial adapter 4 is locked to the vial 7 and a piercing mandrel 57 pierces a vial stopper 76 for liquid transfer.

Abstract: A transport device for medical containers includes a carrier plate which has openings for receiving medical containers, and optionally a trough-shaped container which is formed such that the carrier plate can be inserted in the trough-shaped container. The carrier plate contains a polymer and 7.5 to 50 wt.-% inorganic particles. The optional trough-shaped container contains a polymer and optionally 7.5 to 50 wt.-% inorganic particles.

Abstract: An apparatus for combining a first liquid component 90 stored in a container 125 and a second component stored in a vial 7 by means of negative pressure is disclosed. A tray 1 has a vial cavity 11 and a container cavity 12. A dual-ended transfer needle 131 is fixedly held at the tray 1 at an intermediate needle holding portion 13 between the vial cavity 11 and the container cavity 12 for establishing a fluid communication between the vial 7 and the container 125 by piercing a rubber stopper of the vial and a bottom of the container, respectively. The vial cavity 11 guides the vial 7 along an axial direction AD from an intermediate position towards the transfer position for fluid communication. And the container cavity 12 guides the container 125 along the axial direction AD from an intermediate position towards the transfer position for fluid communication.

Abstract: An apparatus and process for processing outer surfaces of glass containers (50) for use in pharmaceutical, medical or cosmetic applications, said glass containers (50) having a cylindrical main body (52). The process comprises: providing (S1) a plurality of containers (50); separating individual containers from said plurality of containers (50); and sequentially conveying said individual containers (50) through a processing station (1; 61). In the processing station (1; 61), the individual containers (50) are rotated about a longitudinal axis thereof while outer surfaces of the cylindrical main bodies (52) are in contact with a scrubbing member (27; 30, 35), for reducing an adhesive surface behavior of the outer surfaces of the cylindrical main bodies (52) of the individual containers. In this manner the surface properties of glass containers may be enhanced significantly with a cost-efficient and simple processing to thereby prevent undesired ‘stickiness behavior’ of the glass containers.

Abstract: Disclosed is a method of sealing a syringe barrel having a syringe tip with a collar. The syringe tip is sealed with a resilient closure. A tamper evident syringe tip cap comprising a cap member and a sleeve member separated by an annular first breaking line is then pushed over the resilient closure, to couple the proximal end of the sleeve member with the collar. The distal end of the resilient closure is accommodated in the cap member and protrudes beyond the sleeve member. The first breaking line is bridged by a coupling strip. For use of the syringe and providing access to the closure, the first breaking line is broken by pivoting the cap member away. The sleeve member remains coupled to the collar. Further tearing the cap member downward causes breaking a second breaking line provided in the sleeve member, thereby enabling removing the entire syringe tip cap.

Abstract: A tray for positioning, in a fixed positional relationship, a medical vial 7 together with a vial adapter 4 is disclosed. A tray member 10 includes a vial accommodation cavity 11 and a vial adapter accommodation cavity 12, each comprises retaining members 19, 37a, 37b, 35a, 35b, 36a, 36b configured to position the vial adapter 4 and the vial 7 spaced apart from each other and in axial alignment in an intermediate position. The retaining members 19, 37a, 37b, 35a, 35b, 36a, 36b are further configured to guide a relative axial movement of the vial 7 and vial adapter 4 from the intermediate position to a transfer position while maintaining the axial alignment of the vial 7 with the vial adapter 4. In the transfer position the vial adapter 4 is locked to the vial 7 and a piercing mandrel 57 pierces a vial stopper 76 for liquid transfer.

Abstract: A transport or packaging container accommodating a plurality of supporting structures for closures, for transporting or packaging closures for closing cartridges for use in pharmaceutical, medical or cosmetic applications, in which the transport or packaging container is box-shaped and includes a bottom, which is closed or sealed by a seal, upstanding lower side-walls extending essentially perpendicularly from the bottom, a circumferential supporting step extending horizontally from the upstanding lower side-walls, upper side-walls extending upward from said circumferential supporting step, and a circumferential flange formed at upper ends of the upper side-walls; and the plurality of supporting structures for closures is accommodated inside the transport or packaging container.

Abstract: A transport device for medical containers includes a carrier plate which has openings for receiving medical containers, and optionally a trough-shaped container which is formed such that the carrier plate can be inserted in the trough-shaped container. The carrier plate contains a polymer and 7.5 to 50 wt.-% inorganic particles. The optional trough-shaped container contains a polymer and optionally 7.5 to 50 wt.-% inorganic particles.

Abstract: In a method for closing a plurality of medical cartridges (5) a closure nest for supporting a plurality of closures is used, comprising a planar supporting plate having a plurality of receptacles having a plurality of tubular receptacles (61) and retaining structures for reliably accommodating the closures (200). In the method the plurality of medical cartridges (5) is supported in a corresponding cartridge nest. The closure nest is disposed above the cartridge nest so that the receptacles of the closure nest are precisely aligned with the receptacles of the cartridge nest. The closures (200) are then pushed downward out of the receptacles of the closure nest and into the cartridges (5), while the cartridges are supported by the cartridge nest. The closure nest can be directly fed on existing filling and stoppering machine set-ups for processing sealed prefillable syringe barrels, basically without the necessity of changing the set-up.

Abstract: A transport or packaging container accommodating a plurality of supporting structures for closures, for transporting or packaging closures for closing cartridges for use in pharmaceutical, medical or cosmetic applications, in which the transport or packaging container is box-shaped and includes a bottom, which is closed or sealed by a seal, upstanding lower side-walls extending essentially perpendicularly from the bottom, a circumferential supporting step extending horizontally from the upstanding lower side-walls, upper side-walls extending upward from said circumferential supporting step, and a circumferential flange formed at upper ends of the upper side-walls; and the plurality of supporting structures for closures is accommodated inside the transport or packaging container.

Abstract: An apparatus and process for processing outer surfaces of glass containers (50) for use in pharmaceutical, medical or cosmetic applications, said glass containers (50) having a cylindrical main body (52). The process comprises: providing (S1) a plurality of containers (50); separating individual containers from said plurality of containers (50); and sequentially conveying said individual containers (50) through a processing station (1; 61). In the processing station (1; 61), the individual containers (50) are rotated about a longitudinal axis thereof while outer surfaces of the cylindrical main bodies (52) are in contact with a scrubbing member (27; 30, 35), for reducing an adhesive surface behavior of the outer surfaces of the cylindrical main bodies (52) of the individual containers. In this manner the surface properties of glass containers may be enhanced significantly with a cost-efficient and simple processing to thereby prevent undesired ‘stickiness behavior’ of the glass containers.