Abstract: A method and device for execution of deep neural network (DNN) in an internet of things (IoT) edge network are provided. In an embodiment, at least one edge device within communication range of an IoT device are selected. Further, a network for connecting the IoT device with the at least one selected edge device is identified. A split ratio is determined based on an inference time of the DNN and a transmission time required for transmitting output of each layer of DNN from the IoT device to the selected at least one edge device. Finally, a plurality of layers of the DNN are split into a first part and a second part based on the split ratio, and the second part is transmitted to the selected at least one edge device through the identified network. The first part is executed on the IoT device, and the second part is executed on the selected at least one edge device.

Abstract: The present invention provides capsaicin or a capsaicinoid or a TRPV1 agonist for use in the prevention of diabetic ulcers in a patient suffering from diabetic peripheral neuropathy, wherein the capsaicin or capsaicinoid or TRPV1 agonist is administered topically to one or more areas of the skin. Also provided are related methods, uses and kits.

Abstract: This application relates to methods for treating or reducing viral infection in a human subject, comprising administering to the subject a pharmaceutical composition comprising a protease inhibitor.

Abstract: The present invention relates to compositions and methods for treating early T-cell precursor acute lymphoblastic leukemia (ETP T-ALL).

Abstract: Methods of treating peripheral neuropathy induced by cancer chemotherapy and/or of stimulating the regeneration of peripheral sensory nerve fibers, comprising administering topically to one or more areas of the skin capsaicin or a capsaicinoid or topical TRPV1 agonist, to a patient in need thereof, wherein the capsaicin or capsaicinoid or TRPV1 agonist is administered after the patient has received cancer chemotherapy, and wherein the patient is not currently receiving cancer chemotherapy. Related kits comprising capsaicin-containing cutaneous patches for use with said methods.

Abstract: Methods of treating peripheral neuropathy induced by cancer chemotherapy and/or of stimulating the regeneration of peripheral sensory nerve fibers, comprising administering topically to one or more areas of the skin capsaicin or a capsaicinoid or topical TRPV1 agonist, to a patient in need thereof, wherein the capsaicin or capsaicinoid or TRPV1 agonist is administered after the patient has received cancer chemotherapy, and wherein the patient is not currently receiving cancer chemotherapy. Related kits comprising capsaicin-containing cutaneous patches for use with said methods.

Abstract: Heavy Metals contained in industrial waste streams are removed therefrom by flocculation using a source of ferric ions and an alkaline material at a basic pH. Both the flocculated heavy metals and the coagulant chemicals are recovered by acidifying the floc to a pH of between 3.2 and 3.7. This liberates the heavy metals back into solution but does not destroy the floc particles. After separation and removal of the concentrated heavy metal solution, the floc is further acidified to completely dissolve it. This dissolved ferric ion containing solution may then be reused to treat succeeding portions of heavy metal containing waste streams. The concentrated heavy metals solution may also be recycled or the metals contained therein recovered for reuse or disposed of in an acceptable manner.