Patents by Inventor Praveen Kumar Neela

Praveen Kumar Neela has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210032226
    Abstract: The present invention provides dibenzylamine salt of Lifitegrast (XV), and diphenylamine salt of Lifitegrast (XVI) and the use of the above salts in the purification process of Lifitegrast (I). The present invention relates to a process for the preparation of Lifitegrast (I).
    Type: Application
    Filed: April 1, 2019
    Publication date: February 4, 2021
    Inventors: Praveen Kumar NEELA, Guruswamy BATTHINI, Vijay Kumar Gupta GANGISETTY, Ravikanth DUPUD, Srikanth Sai ALUR, Sivakumaran MEENAKSHISUNDERAM
  • Publication number: 20200375983
    Abstract: The present invention is directed towards a process for the preparation of Cariprazine (Ia) or a pharmaceutically acceptable salt thereof, wherein, N,N-dimethyl-1H-imidazole-1-carboxamide alkyl halide (VII) is reacted with trans-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine or a salt thereof (IIa) to produce Cariprazine (Ia) or a pharmaceutically acceptable salt thereof. The present invention is also directed towards amorphous form of Cariprazine hydrochloride (I) and solid dispersion of Cariprazine hydrochloride (I), and its preparation thereof.
    Type: Application
    Filed: November 21, 2018
    Publication date: December 3, 2020
    Applicant: Aurobindo Pharma Ltd
    Inventors: Praveen Kumar NEELA, Guruswamy BATTHINI, Sampath Kumar SANKINENI, Hariprasad Reddy BINGI, Raghavender Reddy MADDI, Sivakumaran MEENAKSHISUNDERAM
  • Patent number: 10774041
    Abstract: The present invention relates to an improved process for the preparation of Apremilast of formula (I).
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: September 15, 2020
    Inventors: Ravi Ponnaiah, Praveen Kumar Neela, Madanlal Anandkumar Lahoti, Srinivas Pardha Gavini Saradhi
  • Publication number: 20190071401
    Abstract: The present invention relates to an improved process for the preparation of Apremilast of formula (I).
    Type: Application
    Filed: January 27, 2017
    Publication date: March 7, 2019
    Inventors: Ravi PONNAIAH, Praveen Kumar NEELA, Madanlal Anandkumar LAHOTI, Srinivas Pardha Gavini SARADHI
  • Patent number: 9682935
    Abstract: A novel process the for preparation of Indacaterol or its pharmaceutically acceptable salts and novel intermediates employed in the preparation thereof that is economically significant for large scale.
    Type: Grant
    Filed: December 27, 2014
    Date of Patent: June 20, 2017
    Inventors: Ponnaiah Ravi, Praveen Kumar Neela, Guruswamy Batthini, Narayana Venugopalarao, Naresh Dongari
  • Patent number: 9199916
    Abstract: The invention is a novel process for the preparation of lacosamide by employing novel intermediates of formula III and IV:
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: December 1, 2015
    Assignee: RAMAMOHAN RAO DAVULURI
    Inventors: Ramamohan Rao Davuluri, Guruswamy Batthini, Swetha Mustyala, Sudheer Kallepalli, Praveen Kumar Neela, Ravi Ponnaiah
  • Patent number: 8940749
    Abstract: An improved process for the synthesis of 3-[2-[4-((6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]-pyrimidin-4-one (Paliperidone) and Paliperidone Palmitate through a novel intermediate (2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-9-hydroxy-4H-pyrido [1,2-a]pyrimidine-4-one Palmitate ester.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: January 27, 2015
    Inventors: Ramamohan Rao Davuluri, Ravi Ponnaiah, Praveen Kumar Neela, Guruswamy Batthini, Telagareddy Venkata Narasimharao, Kosireddy Ravanababu, Kallepally Sudheer
  • Publication number: 20140073787
    Abstract: An improved process for the synthesis of 3-[2-[4-((6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]-pyrimidin-4-one (Paliperidone) and Paliperidone Palmitate through a novel intermediate (2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-9-hydroxy-4H-pyrido [1,2-a]pyrimidine-4-one Palmitate ester.
    Type: Application
    Filed: May 30, 2012
    Publication date: March 13, 2014
    Inventors: Ramamohan Rao Davuluri, Ravi Ponnaiah, Praveen Kumar Neela, Guruswamy Batthini, Telagareddy Venkata Narasimharao, Kosireddy Ravanababu, Kallepally Sudheer
  • Publication number: 20120027816
    Abstract: Provided herein is an impurity of eletriptan, eletriptan N-oxide, (R)-5-[2- (phenylsulfonypethyl]-3-[(1-methyl-2-pyrrolidinyl-N-oxide)methyl]-1H-indole, and a process for the preparation and isolation thereof. Provided further herein is a highly pure eletriptan or a pharmaceutically acceptable salt thereof substantially free of eletriptan N-oxide impurity, processes for the preparation thereof, and pharmaceutical compositions comprising highly pure eletriptan or a pharmaceutically acceptable salt thereof substantially free of eletriptan N-oxide impurity.
    Type: Application
    Filed: February 25, 2010
    Publication date: February 2, 2012
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Vijaya Gopal Kusumba, Sampath Kumar Sankineni, Praveen Kumar Neela, Nitin Sharadchandra Pradhan
  • Publication number: 20110171138
    Abstract: Provided herein is a highly pure deferasirox or a pharmaceutically acceptable salt thereof substantially free of hydrazine impurity, 4-hydrazinobenzoic acid, processes for the preparation thereof, and pharmaceutical compositions comprising highly pure deferasirox or a pharmaceutically acceptable salt thereof substantially free of hydrazine impurity.
    Type: Application
    Filed: June 2, 2009
    Publication date: July 14, 2011
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Rajendra Suryabhan Patil, Kishore Charugundla, Praveen Kumar Neela, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Publication number: 20110171274
    Abstract: Provided herein is an impurity of fesoterodine, fesoterodine dehydroxy impurity, 2-[(1R)-3-[bis(1-methylethy)amino]-1-phenylpropyl]-4-methylphenyl isobutyrate, and a process for preparing and isolating thereof. Provided further herein is a highly pure fesoterodine or a pharmaceutically acceptable salt thereof substantially free of fesoterodine dehydroxy impurity, process for the preparation thereof, and pharmaceutical compositions comprising highly pure fesoterodine or a pharmaceutically acceptable salt thereof substantially free of dehydroxy impurity. Provided also herein is a pharmaceutical composition comprising solid particles of pure fesoterodine fumarate substantially free of dehydroxy impurity, wherein 90 volume-percent of the particles (D90) have a size of less than about 200 microns.
    Type: Application
    Filed: July 21, 2009
    Publication date: July 14, 2011
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Praveen Kumar Neela, Kishore Charugundla, Udhaya Kumar, Nitin Sharadchandra Pradhan
  • Publication number: 20110117200
    Abstract: Provided herein is rasagiline mesylate having a 90 volume-percent of the particles (D90) with a size of about 600 microns to about 1500 microns, and a process for the preparation thereof. Provided also herein are pharmaceutical compositions comprising rasagiline mesylate particles having a particle size which is suitable for homogeneous distribution of the drug substance in a tablet blend, in particular 90 volume-percent of the particles (D90) have a size of about 255 microns to about 1500 microns, and a process the preparation thereof.
    Type: Application
    Filed: March 31, 2009
    Publication date: May 19, 2011
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Nilesh Sudhir Patil, Haushabhau Shivaji Pagire, Praveen Kumar Neela, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Publication number: 20110097413
    Abstract: Provided herein are novel solid state forms of deferasirox salts, process for the preparation, pharmaceutical compositions, and method of treating thereof. The solid state forms of deferasirox salts are useful for preparing deferasirox (I) in high purity.
    Type: Application
    Filed: April 20, 2009
    Publication date: April 28, 2011
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Praveen Kumar Neela, Kishore Charugundla, Rajendra Suryabhan Patil, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Publication number: 20110086103
    Abstract: Provided herein is a novel raantlelate sail of fesoterodine, process for the preparation, pharmaceutics!! compositions, and method of treating thereof. Provided also herein are solid state forms of fesoterodine mandelate, process for the preparation, pharmaceutical compositions, and method of treating thereof. The raandelate salt of fesoterodine is useful for preparing fesoterodine free base or a pharmaceutically acceptable salt thereof; particularly fesoterodine fumaraie, in high purity.
    Type: Application
    Filed: April 6, 2009
    Publication date: April 14, 2011
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Kishore Charugundla, Udhaya Kumar, Praveen Kumar Neela, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Publication number: 20100297241
    Abstract: The present invention provides a novel amorphous form of fesoterodine fumarate, process for preparation, pharmaceutical compositions, and method of treating thereof.
    Type: Application
    Filed: October 1, 2008
    Publication date: November 25, 2010
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Kishore Charugundla, Udhaya Kumar Chandramohan, Nitin Sharadchandra Pradhan, Jon Valgeirsson, Praveen Kumar Neela
  • Publication number: 20100285075
    Abstract: The present invention relates to novel hemioxalate salt of eletriptan, process for preparation, pharmaceutical compositions, and method of treating thereof. The present invention relates to solid forms of eletriptan hemioxalate, processes for preparation, pharmaceutical compositions, and method of treating thereof. The solid form of eletriptan hemioxalate is useful for preparing eletriptan free base or a pharmaceutically acceptable salt thereof, particularly eletriptan hydrobromide, in high purity. The present invention also provides a process for preparing substantially pure eletriptan hydrobromide using eletriptan hemioxalate.
    Type: Application
    Filed: December 17, 2008
    Publication date: November 11, 2010
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Vijaya Gopal Kusumba, Sampath Kumar Sankineni, Praveen Kumar Neela, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Publication number: 20100217034
    Abstract: Disclosed herein is an improved, commercially viable and industrially advantageous process for the preparation of Fesoterodine or a pharmaceutically acceptable salt thereof in high yield and purity. Disclosed also herein is an improved and industrially advantageous optical resolution method of racemic (±)-N,N-Diisopropyl-3-(2-benzyloxy-5-bromophenyl)-3-phenylpropylamine and use thereof for the preparation of Fesoterodine.
    Type: Application
    Filed: September 22, 2008
    Publication date: August 26, 2010
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Kishore Charugundla, Udhaya Kumar, Rajendra Suryabhan Patil, Praveen Kumar Neela, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Publication number: 20100204296
    Abstract: The present invention provides a novel and stable amorphous form of darifenacin free base, process for preparation, pharmaceutical compositions, and method of treating thereof. The present invention further provides a novel and stable polymorphic form of darifenacin hydrobromide, process for preparation, pharmaceutical compositions, and method of treating thereof.
    Type: Application
    Filed: June 9, 2008
    Publication date: August 12, 2010
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Eswara Rao Kodali, Sreekanth Medikonduri, Praveen Kumar Neela, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Publication number: 20100063299
    Abstract: Disclosed herein is an improved, commercially viable and industrially advantageous process for the preparation of Irbesartan, or a pharmaceutically acceptable salt thereof, in high yield and purity.
    Type: Application
    Filed: March 6, 2008
    Publication date: March 11, 2010
    Inventors: Udhaya Kumar, Praveen Kumar Neela, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Publication number: 20040249211
    Abstract: The present invention relates to a cost effective and industrially advantageous process for the preparation of tolterodine and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: May 18, 2004
    Publication date: December 9, 2004
    Inventors: Yatendra Kumar, Mohan Prasad, Praveen Kumar Neela, Satyananda Misra