Abstract: Various systems and methods for implementing tiered access to regions of interest in video frames are described herein. A system for implementing tiered access to regions of interest in video frames, comprising: a memory device to store a mapping table, the mapping table to store a correspondence between a protection level and a consumer; video processing circuitry to: compress a video stream using a lossless video compression standard, the video stream comprising a plurality of frames, each frame comprising a plurality of image blocks; and encrypt each block in each frame of the video stream using an encryption key; and inference circuitry to: use an object detection and classification process on the video stream to identify an object in the video stream; access a policy store to determine a corresponding protection level for the object; and store the corresponding protection level in lossless video compression metadata.