Patents by Inventor Praveen SETHUPATHY

Praveen SETHUPATHY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human fibrolamellar hepatocellular carcinomas (hFL-HCCs)
    Patent number: 11932877
    Abstract: The present disclosure provides a model of human fibrolamellar hepatocellular carcinoma (FL-HCC) cells maintained as a transplantable tumor line in a host and a method to establish a transplantable human FL-HCC tumor line. Methods of ex vivo cultures of the FL-HCC are provided. Methods of diagnosing and treating FL-HCC tumors are also provided.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: March 19, 2024
    Assignee: University of North Carolina at Chapel Hill
    Inventors: Eliane Wauthier, Tsunekazu Oikawa, Timothy Anh-Hieu Dinh, Praveen Sethupathy, Lola M. Reid
  • COMPOSITIONS FOR THE TREATMENT OF NASH AND ASSOCIATED DISORDERS AND METHODS OF USING SAME
    Publication number: 20230210883
    Abstract: The present disclosure describes, in part, compositions and methods for the treatment of NASH and NASH-associated diseases. Compositions comprising an agent able to increases the expression, activity, or level of one more of a protective miRNA, preferably miR-375 are provided that may be used for the treatment of liver and/or liver-associated disease is treated in the subject.
    Type: Application
    Filed: March 15, 2021
    Publication date: July 6, 2023
    Inventors: Phillip James WHITE, Praveen SETHUPATHY, Robert McGARRAH
  • COMPOSITIONS AND METHODS FOR BIOENGINEERED TISSUES
    Publication number: 20200080061
    Abstract: The present disclosure provides methods for producing bioengineered tissue along with an apparatus and other relevant compositions employed in generation thereof.
    Type: Application
    Filed: November 12, 2019
    Publication date: March 12, 2020
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Arial Dawn Hanson, Mitsuo Yamauchi, Eliane Lucie Wauthier, Timothy Anh-Hieu Dinh, Praveen Sethupathy, Lola M. Reid
  • HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (hFL-HCCS)
    Publication number: 20190161735
    Abstract: The present disclosure provides a model of human fibrolamellar hepatocellular carcinoma (FL-HCC) cells maintained as a transplantable tumor line in a host and a method to establish a transplantable human FL-HCC tumor line. Methods of ex vivo cultures of the FL-HCC are provided. Methods of diagnosing and treating FL-HCC tumors are also provided.
    Type: Application
    Filed: June 18, 2018
    Publication date: May 30, 2019
    Applicant: University of North Carolina at Chapel Hill
    Inventors: Eliane Wauthier, Tsunekazu OIKAWA, Timothy Anh-Hieu DINH, Praveen SETHUPATHY, Lola M. REID
  • COMPOSITIONS AND METHODS FOR BIOENGINEERED TISSUES
    Publication number: 20170369849
    Abstract: The present disclosure provides methods for producing bioengineered tissue along with an apparatus and other relevant compositions employed in generation thereof.
    Type: Application
    Filed: May 3, 2017
    Publication date: December 28, 2017
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Ariel Dawn HANSON, Mitsuo YAMAUCHI, Eliane Lucie WAUTHIER, Timothy Anh-Hieu DINH, Praveen SETHUPATHY, Lola M. REID
  • HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (hFL-HCCS)
    Publication number: 20160257937
    Abstract: The present disclosure provides a model of human fibrolamellar hepatocellular carcinoma (FL-HCC) cells maintained as a transplantable tumor line in a host and a method to establish a transplantable human FL-HCC tumor line. Methods of ex vivo cultures of the FL-HCC are provided. Methods of diagnosing and treating FL-HCC tumors are also provided.
    Type: Application
    Filed: March 4, 2016
    Publication date: September 8, 2016
    Applicant: University of North Carolina at Chapel Hill
    Inventors: Eliane WAUTHIER, Tsunekazu OIKAWA, Timothy Anh-Hieu DINH, Praveen SETHUPATHY, Lola M. REID