Patents by Inventor Praveena Mohan

Praveena Mohan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbubble complexes and methods of use
    Patent number: 11007212
    Abstract: The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfluorocarbon gas, a therapeutic agent, a bifunctional linker having one end attached to the therapeutic agent and the other attached to a ligand and wherein the ligand is bound to the other shell of the microbubble through hydrophobic interactions. Also included are methods for delivering the aforementioned microbubble complex to a tissue target.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: May 18, 2021
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Anup Sood, Lisa Anne Lowery, Praveena Mohan, James Edward Rothman, John Donald Burczak, Hae Won Lim
  • MICROBUBBLE COMPLEXES AND METHODS OF USE
    Publication number: 20190060347
    Abstract: The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfluorocarbon gas, a therapeutic agent, a bifunctional linker having one end attached to the therapeutic agent and the other attached to a ligand and wherein the ligand is bound to the other shell of the microbubble through hydrophobic interactions. Also included are methods for delivering the aforementioned microbubble complex to a tissue target.
    Type: Application
    Filed: June 25, 2018
    Publication date: February 28, 2019
    Inventors: Anup Sood, Lisa Anne Lowery, Praveena Mohan, James Edward Rothman, John Donald Burczak, Hae Won Lim
  • Microbubble complexes and methods of use
    Patent number: 10004760
    Abstract: The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfluorocarbon gas, a therapeutic agent, a bifunctional linker having one end attached to the therapeutic agent and the other attached to a ligand and wherein the ligand is bound to the other shell of the microbubble through hydrophobic interactions. Also included are methods for delivering the aforementioned microbubble complex to a tissue target.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: June 26, 2018
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Praveena Mohan, Anup Sood, James Edward Rothman, John Donald Burczak, Hae Won Lim, Lisa Anne Lowery
  • MICROBUBBLE COMPLEXES AND METHODS OF USE
    Publication number: 20170007636
    Abstract: The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfluorocarbon gas, a therapeutic agent, a bifunctional linker having one end attached to the therapeutic agent and the other attached to a ligand and wherein the ligand is bound to the other shell of the microbubble through hydrophobic interactions. Also included are methods for delivering the aforementioned microbubble complex to a tissue target.
    Type: Application
    Filed: July 26, 2016
    Publication date: January 12, 2017
    Inventors: Praveena Mohan, Anup Sood, James Edward Rothman, John Donald Burczak, Hae Won Lim, Lisa Anne Lowery
  • MICROBUBBLE COMPLEXES AND METHODS OF USE
    Publication number: 20130072854
    Abstract: The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfluorocarbon gas, a therapeutic agent, a bifunctional linker having one end attached to the therapeutic agent and the other attached to a ligand and wherein the ligand is bound to the other shell of the microbubble through hydrophobic interactions. Also included are methods for delivering the aforementioned microbubble complex to a tissue target.
    Type: Application
    Filed: June 20, 2012
    Publication date: March 21, 2013
    Applicant: General Electric Company
    Inventors: Praveena Mohan, Anup Sood, James Edward Rothman, John Donald Burczak, Hae Won Lim, Lisa Anne Lowery