Patents by Inventor Prediman K. Shah

Prediman K. Shah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEPTIDE-BASED IMMUNIZATION THERAPY FOR TREATMENT OF ATHEROSCLEROSIS
    Publication number: 20090226475
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Application
    Filed: February 27, 2009
    Publication date: September 10, 2009
    Applicants: FORSKARPATENT I SYD, CEDARS SINAI MEDICAL CENTER
    Inventors: Jan Nilsson, Prediman K. Shah
  • ANTIBODIES AGAINST A PEPTIDE EPITOPE OF APOLIPOROTEIN B
    Publication number: 20090202523
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Application
    Filed: February 27, 2009
    Publication date: August 13, 2009
    Applicants: FORSKARPATENT I SYD, CEDARS SINAI MEDICAL CENTER
    Inventors: Jan Nilsson, Prediman K. Shah
  • Peptide epitopes of apolipoprotein B
    Patent number: 7556811
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: July 7, 2009
    Assignees: Forskarpatent I Syd, Cedars Sinai Medical Center
    Inventors: Jan Nilsson, Prediman K. Shah
  • Peptide epitopes of apolipoprotein B
    Patent number: 7544360
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: June 9, 2009
    Assignees: Forskarpatent I Syd, Cedars Sinai Medical Center
    Inventors: Jan Nilsson, Prediman K. Shah
  • Antibodies against a peptide epitope of apolipoprotein B
    Patent number: 7537758
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Grant
    Filed: July 12, 2006
    Date of Patent: May 26, 2009
    Assignees: Forskarpatent I SYD AB, Cedars Sinai Medical Center
    Inventors: Jan Nilsson, Prediman K. Shah
  • PEPTIDE EPITOPES OF APOLIPOPROTEIN B
    Publication number: 20090117178
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 7, 2009
    Applicants: FORSKARPATENT I SYD, CEDARS SINAI MEDICAL CENTER
    Inventors: Jan Nilsson, Prediman K. Shah
  • PEPTIDE EPITOPES OF APOLIPOPROTEIN B
    Publication number: 20090117137
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 7, 2009
    Applicants: FORSKARPATENT I SYD, CEDARS SINAI MEDICAL CENTER
    Inventors: Jan Nilsson, Prediman K. Shah
  • Peptide epitopes of apolipoprotein B
    Patent number: 7527795
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Grant
    Filed: October 25, 2007
    Date of Patent: May 5, 2009
    Assignees: Forskarpatent I Syd, Cedars Sinai Medical Center
    Inventors: Jan Nilsson, Prediman K. Shah
  • Peptide epitopes of apolipoprotein B
    Patent number: 7528225
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: May 5, 2009
    Assignees: Forskarpapatent I Syd, Cedars Sinai Medical Center
    Inventors: Jan Nilsson, Prediman K. Shah
  • PEPTIDE EPITOPES OF APOLIPOPROTEIN B
    Publication number: 20080317837
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Application
    Filed: October 31, 2007
    Publication date: December 25, 2008
    Applicants: FORSKARPATENT I SYD, CEDARS SINAI MEDICAL CENTER
    Inventors: Jan Nilsson, Prediman K. Shah
  • Methods for Treating Vascular Disease
    Publication number: 20080286285
    Abstract: Compositions and methods included herein describe the treatment of atherosclerosis and other vascular diseases such as thrombosis, restenosis after angioplasty and/or stenting, and vein-graft disease after bypass surgery, by inhibition of the expression or biologic activity of the toll-like receptor 4 (TLR4) and/or myeloid differentiation factor 88 (MyD88). TLR4 cell signal transduction is at least partially responsible for the manifestation, continuation, and/or worsening of atherosclerosis and other forms of vascular disease. The present invention provides several means with which to inhibit this signal transduction pathway by affecting the biological activity of the TLR4 receptor and/or MyD88.
    Type: Application
    Filed: May 25, 2005
    Publication date: November 20, 2008
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Moshe Arditi, Tripathi Rajavashisth, Prediman K. Shah
  • Stent coated with magnesium-based compound for reducing thrombosis
    Patent number: 7452373
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: November 18, 2008
    Assignee: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • PEPTIDE EPITOPES OF APOLIPOPROTEIN B
    Publication number: 20080274170
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Application
    Filed: October 25, 2007
    Publication date: November 6, 2008
    Applicants: FORSKARPATENT I SYD, CEDARS SINAI MEDICAL CENTER
    Inventors: Jan Nilsson, Prediman K. Shah
  • PEPTIDE EPITOPES OF APOLIPOPROTEIN B
    Publication number: 20080268029
    Abstract: The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, using one or more of said antibodies.
    Type: Application
    Filed: October 31, 2007
    Publication date: October 30, 2008
    Applicants: FORSKARPATENT I SYD, CEDARS SINAI MEDICAL CENTER
    Inventors: Jan Nilsson, Prediman K. Shah
  • Use of Eotaxin as a Diagnostic Indicator For Atherosclerosis and Vascular Inflammation
    Publication number: 20080268478
    Abstract: The invention disclosed herein relates to the detection or diagnosis of atherosclerosis by measuring the level of the protein eotaxin in an individual's serum. The presence of eotaxin above levels specified herein is indicative that atherosclerosis may be present. Detection of elevated eotaxin levels in serum may provide a means to diagnose atherosclerosis prior to the onset of symptoms.
    Type: Application
    Filed: February 28, 2006
    Publication date: October 30, 2008
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Behrooz Sharifi, Prediman K. Shah, Lai Wang
  • Method of reducing thrombosis and complications after arterial angioplasty using stent coated with magnesium-based compound
    Patent number: 7279183
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: October 9, 2007
    Assignee: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Instrument coated with magnesium-based compound for reducing thrombosis
    Publication number: 20040247642
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Application
    Filed: December 24, 2003
    Publication date: December 9, 2004
    Applicant: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Method of inhibiting thrombosis and complications after angioplasty using magnesium-based compound
    Publication number: 20040146586
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Application
    Filed: December 24, 2003
    Publication date: July 29, 2004
    Applicant: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Method of reducing thrombosis and complications after arterial angioplasty using stent coated with magnesium-based compound
    Publication number: 20040138739
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Application
    Filed: December 24, 2003
    Publication date: July 15, 2004
    Applicant: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Prevention of in-stent thrombosis and complications after arterial angioplasty with stent placement using magnesium
    Patent number: 6692772
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: February 17, 2004
    Assignee: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah