Patents by Inventor Preethi Ramaiya
Preethi Ramaiya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11203790Abstract: The present invention relates to glucoamylase variants, polynucleotides encoding the variants, methods of producing the variants, and methods of using the variants. Also described are the use of glucoamylases of the invention for starch conversion to produce fermentation products, such as ethanol, and syrups, such as glucose. The invention also relates to a composition comprising a glucoamylase variant of the invention.Type: GrantFiled: October 18, 2019Date of Patent: December 21, 2021Assignee: NOVOZYMES A/SInventors: Shikha Gupta, Allan Svendsen, Vivek Srivastava, Marco Malten, Thomas Agersten Poulsen, Preethi Ramaiya, Beth Nelson, Vasudeva Prahlada Rao, Padmavathi Balumuri
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Patent number: 11046736Abstract: The instant invention relates to filamentous fungal host cells producing and secreting a heterologous polypeptide of interest, said mutant host cell comprising and expressing a mutated ireA gene or a homologue thereof encoding a modified IreA polypeptide or a homologue thereof, said modified IreA polypeptide or homologue thereof comprising amino acid substitutions in 5 positions corresponding to positions 81 and 84 in the Aspergillus niger IreA amino acid sequence shown in SEQ ID NO:16, as well as methods of producing a polypeptide of interest in said cells and methods for constructing said cells.Type: GrantFiled: July 19, 2017Date of Patent: June 29, 2021Assignee: Novozymes A/SInventors: Hiroshi Teramoto, Kaihei Kojima, Preethi Ramaiya
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Publication number: 20200157155Abstract: The invention provides an improved host strain for production of desired protein.Type: ApplicationFiled: May 17, 2019Publication date: May 21, 2020Applicant: Albumedix LTD.Inventors: Christopher John Arthur Finnis, Jennifer Mary Mclaughlan, Per Kristoffer Nordeide, Preethi Ramaiya
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Publication number: 20200140965Abstract: The present invention relates to glucoamylase variants having an increase in specific activity and/or an increase in melting temperature measured by TSA of at least 0.5 degrees Celsius, and further wherein the variants have at least at least 85%, at least 90%, at least 95% identity, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100%, sequence identity to the amino acid sequence of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.Type: ApplicationFiled: October 18, 2019Publication date: May 7, 2020Applicant: NOVOZYMES A/SInventors: Shikha Gupta, Allan Svendsen, Vivek Srivastava, Marco Malten, Thomas Agersten Poulsen, Preethi Ramaiya, Beth Nelson, Vasudeva Prahlada Rao, Padmavathi Balumuri
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Patent number: 10494685Abstract: The present invention relates to glucoamylase variants having an increase in specific activity and/or an increase in melting temperature measured by TSA of at least 0.5 degrees Celsius, and further wherein the variants have at least at least 85%, at least 90%, at least 95% identity, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100%, sequence identity to the amino acid sequence of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.Type: GrantFiled: October 12, 2016Date of Patent: December 3, 2019Assignee: NOVOZYMES A/SInventors: Shikha Gupta, Allan Svendsen, Vivek Srivastava, Marco Malten, Thomas Agersten Poulsen, Preethi Ramaiya, Beth Nelson, Vasudeva P. Rao, Padmavathi Balumuri
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Publication number: 20190169238Abstract: The instant invention relates to filamentous fungal host cells producing and secreting a heterologous polypeptide of interest, said mutant host cell comprising and expressing a mutated ireA gene or a homologue thereof encoding a modified IreA polypeptide or a homologue thereof, said modified IreA polypeptide or homologue thereof comprising amino acid substitutions in 5 positions corresponding to positions 81 and 84 in the Aspergillus niger IreA amino acid sequence shown in SEQ ID NO:16, as well as methods of producing a polypeptide of interest in said cells and methods for constructing said cells.Type: ApplicationFiled: July 19, 2017Publication date: June 6, 2019Applicant: Novozymes A/SInventors: Hiroshi Teramoto, Kaihei Kojima, Preethi Ramaiya
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Publication number: 20190048413Abstract: The present invention enables the determination by NGS of the full nucleotide sequence of one or more polynucleotides of interest that are more than 800 bp in length after only one round of PCR amplification and subsequent fragmentation by adding at least one known oligonucleotide index to at least one end of each polynucleotide to produce elongated polynucleotides, wherein each known oligonucleotide index added to each polynucleotide is unique; fragmenting the elongated polynucleotides; sequencing the resulting fragments with paired forward and reverse reads using bridge amplification and next-generation sequencing; sorting the paired sequences based on the known oligonucleotide; and performing manual or in silico assembly of the sorted paired sequences, thereby providing the full coding sequence of each of the multitude of polynucleotides.Type: ApplicationFiled: February 23, 2017Publication date: February 14, 2019Applicant: NOVOZYMES A/SInventors: Marco Malten, Thomas Agersten Poulsen, Preethi Ramaiya, Michael Bargisen, Beth Nelson
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Publication number: 20180298456Abstract: The present invention relates to glucoamylase variants having an increase in specific activity and/or an increase in melting temperature measured by TSA of at least 0.5 degrees Celsius, and further wherein the variants have at least at least 85%, at least 90%, at least 95% identity, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100%, sequence identity to the amino acid sequence of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.Type: ApplicationFiled: October 12, 2016Publication date: October 18, 2018Applicant: NOVOZYMES A/SInventors: Shikha Gupta, Allan Svendsen, Vivek Srivastava, Marco Malten, Thomas Agersten Poulsen, Preethi Ramaiya, Beth Nelson, Vasudeva P. Rao, Padmavathi Balumuri
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Patent number: 10023618Abstract: The invention provides an improved host strain for production of desired protein.Type: GrantFiled: August 15, 2017Date of Patent: July 17, 2018Assignee: Albumedix A/SInventors: Christopher John Arthur Finnis, Jennifer Mary Mclaughlan, Per Kristoffer Nordeide, Preethi Ramaiya
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Publication number: 20180022785Abstract: The invention provides an improved host strain for production of desired protein.Type: ApplicationFiled: August 15, 2017Publication date: January 25, 2018Applicant: Albumedix A/SInventors: Christopher John Arthur Finnis, Jennifer Mary Mclaughlan, Per Kristoffer Nordeide, Preethi Ramaiya
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Publication number: 20180009856Abstract: The invention provides an improved host strain for production of desired protein.Type: ApplicationFiled: May 12, 2017Publication date: January 11, 2018Applicant: Albumedix A/SInventors: Christopher John Arthur Finnis, Jennifer Mary Mclaughlan, Per Kristoffer Nordeide, Preethi Ramaiya
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Publication number: 20160002591Abstract: The present invention relates to isolated polynucleotides of the chromosome of Bacillus licheniformis SJ1904 that encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing biologically active substances encoded by the polynucleotides and to methods of using the isolated polynucleotides of the complete chromosome of Bacillus licheniformis SJ1904.Type: ApplicationFiled: July 20, 2015Publication date: January 7, 2016Applicant: NOVOZYMES INC.Inventors: Randy Berka, Michael Rey, Preethi Ramaiya
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Publication number: 20150259389Abstract: The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis SJ1904 (ATCC PTA-7992). The present invention also relates to isolated polynucleotides of the chromosome of Bacillus licheniformis SJ1904 that encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing biologically active substances encoded by the polynucleotides and to methods of using the isolated polynucleotides of the complete chromosome of Bacillus licheniformis SJ1904.Type: ApplicationFiled: August 7, 2013Publication date: September 17, 2015Inventors: Randy Berka, Michael Rey, Preethi Ramaiya
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Publication number: 20150045535Abstract: The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis SJ1904 (ATCC PTA-7992). The present invention also relates to isolated polynucleotides of the chromosome of Bacillus licheniformis SJ1904 that encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing biologically active substances encoded by the polynucleotides and to methods of using the isolated polynucleotides of the complete chromosome of Bacillus licheniformis SJ1904.Type: ApplicationFiled: August 7, 2013Publication date: February 12, 2015Inventors: Randy Berka, Michael Rey, Preethi Ramaiya
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Patent number: 8168417Abstract: The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis. The present invention also relates to isolated genes of the chromosome of Bacillus licheniformis which encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the genes as well as methods for producing biologically active substances encoded by the genes and to methods of using the isolated genes of the complete chromosome of Bacillus licheniformis.Type: GrantFiled: December 17, 2010Date of Patent: May 1, 2012Assignees: Novozymes A/S, Novozymes, Inc.Inventors: Randy Berka, Michael Rey, Preethi Ramaiya, Jens Tønne Andersen, Michael Dolberg Rasmussen, Peter Bjarke Olsen
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Publication number: 20120070881Abstract: The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis. The present invention also relates to isolated genes of the chromosome of Bacillus licheniformis which encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the genes as well as methods for producing biologically active substances encoded by the genes and to methods of using the isolated genes of the complete chromosome of Bacillus licheniformis.Type: ApplicationFiled: November 28, 2011Publication date: March 22, 2012Applicants: NOVOZYMES A/S, NOVOZYMES, INC.Inventors: Randy Berka, Michael Rey, Preethi Ramaiya, Jens Tonne Andersen, Michael Dolberg Rasmussen, Peter Bjarke Olsen
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Publication number: 20110086407Abstract: The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis. The present invention also relates to isolated genes of the chromosome of Bacillus licheniformis which encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the genes as well as methods for producing biologically active substances encoded by the genes and to methods of using the isolated genes of the complete chromosome of Bacillus licheniformis.Type: ApplicationFiled: December 17, 2010Publication date: April 14, 2011Applicants: Novozymes A/S, Novozymes, Inc.Inventors: Randy Berka, Michael Rey, Preethi Ramaiya, Jens Tønne Andersen, Michael Dolberg Rasmussen, Peter Bjarke Olsen
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Patent number: 7863032Abstract: The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis. The present invention also relates to isolated genes of the chromosome of Bacillus licheniformis which encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the genes as well as methods for producing biologically active substances encoded by the genes and to methods of using the isolated genes of the complete chromosome of Bacillus licheniformis.Type: GrantFiled: February 9, 2009Date of Patent: January 4, 2011Assignees: Novozymes, Inc., Novozymes A/SInventors: Randy Berka, Michael Rey, Preethi Ramaiya, Jens Tønne Andersen, Michael Dolberg Rasmussen, Peter Bjarke Olsen
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Publication number: 20100064393Abstract: The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis SJ1904 (ATCC PTA-7992). The present invention also relates to isolated polynucleotides of the chromosome of Bacillus licheniformis SJ1904 that encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing biologically active substances encoded by the polynucleotides and to methods of using the isolated polynucleotides of the complete chromosome of Bacillus licheniformis SJ1904.Type: ApplicationFiled: November 29, 2007Publication date: March 11, 2010Applicant: Novozymes, Inc.Inventors: Randy Berka, Michael Rey, Preethi Ramaiya
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Publication number: 20090275104Abstract: The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis. The present invention also relates to isolated genes of the chromosome of Bacillus licheniformis which encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the genes as well as methods for producing biologically active substances encoded by the genes and to methods of using the isolated genes of the complete chromosome of Bacillus licheniformis.Type: ApplicationFiled: February 9, 2009Publication date: November 5, 2009Applicants: Novozymes A/S, Novozymes, Inc.Inventors: Randy Berka, Michael Rey, Preethi Ramaiya, Jens Tonne Andersen, Michael Dolberg Rasmussen, Peter Bjarke Olsen