Patents by Inventor Preeti G. Lal
Preeti G. Lal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8569445Abstract: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.Type: GrantFiled: September 14, 2009Date of Patent: October 29, 2013Assignee: Incyte CorporationInventors: Henry Yue, Monique G. Yao, Ameena R. Gandhi, Mariah R. Baughn, Anita Swarnakar, Narinder Chawla, Madhusudan M. Sanjanwala, Michael Thorton, Vicki S. Elliott, Yan Lu, Kimberly J. Gietzen, Neil Burford, Li Ding, April J. A. Hafalia, Y. Tom Tang, Olga Bandman, Bridget A. Warren, Cynthia D. Honchell, Dyung Aina M. Lu, Kavitha Thangavelu, Sally Lee, Yuming Xu, Junming Yang, Preeti G. Lal, Bao Tran, Craig H. Ison, Brendan M. Duggan, Stephanie K. Sapperstein
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Publication number: 20130243781Abstract: The invention provides cDNAs which encodes a signal peptide-containing proteins. It also provides for the use of a cDNA, protein, and antibody in the diagnosis, prognosis, treatment and evaluation of therapies for cancer. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.Type: ApplicationFiled: February 8, 2013Publication date: September 19, 2013Applicant: Incyte CorporationInventors: Preeti G. LAL, Janice Au-Young, Roopa Reddy, Lynn E. Murry, Preete Mathur
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Publication number: 20130190250Abstract: The invention provides a human signal peptide-containing proteins (SIGP) and polynucleotides which identify and encode SIGP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of SIGP.Type: ApplicationFiled: September 14, 2012Publication date: July 25, 2013Inventors: Preeti G. Lal, Jennifer L. Jackson, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn, Susan K. Sather, Purvi Shah
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Patent number: 8206947Abstract: The invention provides human transmembrane proteins (HTMPN) and polynucleotides which identify and encode HTMPN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HTMPN.Type: GrantFiled: November 8, 2006Date of Patent: June 26, 2012Assignee: Incyte CorporationInventors: Y. Tom Tang, Preeti G. Lal, Jennifer L. Jackson, Henry Yue, Karl J. Guegler, Neil C. Corley, Olga Bandman, Chandra S. Arvizu, Gina A. Gorgone Simone, Matthew R. Kaser, Mariah R. Baughn, Janice K. Au-Young
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Patent number: 8153398Abstract: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.Type: GrantFiled: June 9, 2009Date of Patent: April 10, 2012Assignee: Incyte CorporationInventors: Preeti G. Lal, Y. Tom Tang, Gina A. Gorgone Simone, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn, Ingrid E. Akerblom, Janice K. Au-Young, Henry Yue, Chandra S. Arvizu, Roopa M. Reddy, Jennifer L. Hillman, Olga Bandman
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Patent number: 8148067Abstract: The invention presents a method of diagnosing or monitoring the status of systemic lupus erythematosus (SLE) in a subject or patient comprising detecting the expression of all genes of a diagnostic set in the subject or patient wherein the diagnostic set comprises two or more genes having expression correlated with the classification or status of SLE; and diagnosing or monitoring the status of SLE in the subject or patient by applying at least one statistical method to the expression of the genes of the diagnostic set.Type: GrantFiled: November 9, 2007Date of Patent: April 3, 2012Assignee: Xdx, Inc.Inventors: Preeti G. Lal, Gavin E. Williams, Kirk E. Fry, Jingtao Sun, Russell L. Dedrick
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Publication number: 20100099617Abstract: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.Type: ApplicationFiled: September 14, 2009Publication date: April 22, 2010Inventors: Henry Yue, Monique G. Yao, Ameena R. Gandhi, Mariah R. Baughn, Anita Swarnakar, Narinder K. Chawla, Madhusudan M. Sanjanwala, Michael B. Thornton, Vicki S. Elliott, Yan Lu, Kimberly J. Gietzen, Neil Burford, Li Ding, April J. A. Hafalia, Y. Tom Tang, Olga Bandman, Bridget A. Warren, Cynthia D. Honchell, Dyung Aina M. Lu, Kavitha Thangavelu, Sally Lee, Yuming Xu, Junming Yang, Preeti G. Lal, Bao Tran, Craig H. Ison, Brendan M. Duggan, Stephanie K. Sapperstein
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Publication number: 20100092989Abstract: Described herein is a system for monitoring gene expression for diagnosing and monitoring inflammation disorders, and for monitoring gene expression in inflammation disorders in response to a particular drug treatment regimen. This system for detecting nucleic acid expression in a body fluid uses an isolated polynucleotide to detect expression of a nucleic acid comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 5; SEQ ID NO:11; SEQ ID NO:17; and SEQ ID NO: 23. These nucleic acids are differentially expressed in body fluid in an individual with a disease criterion for a disease as listed in Table 1 as compared to an individual without the disease criterion.Type: ApplicationFiled: December 10, 2009Publication date: April 15, 2010Applicant: XDx, Inc.Inventors: Jay WOHLGEMUTH, Darren Tayama, Dirk Walther, Preeti G. Lal
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Patent number: 7645575Abstract: Described herein is a system for monitoring gene expression for diagnosing and monitoring inflammation disorders, and for monitoring gene expression in inflammation disorders in response to a particular drug treatment regimen. This system for detecting nucleic acid expression in a body fluid uses an isolated polynucleotide to detect expression of a nucleic acid comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 5; SEQ ID NO:11; SEQ ID NO:17; and SEQ ID NO: 23. These nucleic acids are differentially expressed in body fluid in an individual with a disease criterion for a disease as listed in Table 1 as compared to an individual without the disease criterion.Type: GrantFiled: September 8, 2005Date of Patent: January 12, 2010Assignee: XDX, Inc.Inventors: Jay Wohlgemuth, Darren Tayama, Dirk Walther, Preeti G. Lal
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Publication number: 20090298060Abstract: The invention presents a method of diagnosing or monitoring the status of systemic lupus erythematosus (SLE) in a subject or patient comprising detecting the expression of all genes of a diagnostic set in the subject or patient wherein the diagnostic set comprises two or more genes having expression correlated with the classification or status of SLE; and diagnosing or monitoring the status of SLE in the subject or patient by applying at least one statistical method to the expression of the genes of the diagnostic set.Type: ApplicationFiled: November 9, 2007Publication date: December 3, 2009Applicant: XDX, Inc.Inventors: Preeti G. LAL, Gavin E. Williams, Kirk E. Fry, Jingtao Sun, Russell L. Dedrick
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Patent number: 7608704Abstract: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.Type: GrantFiled: March 20, 2006Date of Patent: October 27, 2009Assignee: Incyte CorporationInventors: Henry Yue, Monique G. Yao, Ameena R. Gandhi, Mariah R. Baughn, Anita Swarnakar, Narinder Chawla, Madhusudan M. Sanjanwala, Michael Thorton, Vicki S. Elliott, Yan Lu, Kimberly J. Gietzen, Neil Burford, Li Ding, April J. A. Hafalia, Y. Tom Tang, Olga Bandman, Bridget A. Warren, Cynthia D. Honchell, Dyung Aina M. Lu, Kavitha Thangavelu, Sally Lee, Yuming Xu, Junming Yang, Preeti G. Lal, Bao Tran, Craig H. Ison, Brendan M. Duggan, Stephanie K. Sapperstein
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Publication number: 20080241158Abstract: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.Type: ApplicationFiled: August 29, 2007Publication date: October 2, 2008Inventors: Preeti G. Lal, Richard C. Graul, April J.A. Hafalia, Narinder K. Chawla, Michael B. Thornton, Danniel B. Nguyen, Yan Lu, Ameena R. Gandhi, Chandra S. Arvizu, Deborah A. Kallick, Mariah R. Baughn, Jayalaxmi Ramkumar, Catherine M. Tribouley, Ernestine A. Lee, Li Ding, Neil Burford, Monique G. Yao, Junming Yang, Jennifer A. Griffin
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Publication number: 20080181895Abstract: The invention provides cDNAs which encodes a signal peptide-containing proteins. It also provides for the use of a cDNA, protein, and antibody in the diagnosis, prognosis, treatment and evaluation of therapies for cancer. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.Type: ApplicationFiled: November 6, 2007Publication date: July 31, 2008Inventors: Preeti G. Lal, Janice Au-Young, Roopa Reddy, Lynn E. Murry, Preete Mathur
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Patent number: 7321023Abstract: The invention provides cDNAs which encodes a signal peptide-containing proteins. It also provides for the use of a cDNA, protein, and antibody in the diagnosis, prognosis, treatment and evaluation of therapies for cancer. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.Type: GrantFiled: October 1, 2001Date of Patent: January 22, 2008Assignee: Incyte CorporationInventors: Preeti G. Lal, Janice Au-Young, Roopa Reddy, Lynn E. Murry, Preete Mathur
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Patent number: 7029897Abstract: The invention provides human kinases and phosphatases (KAP) and polnucleotides which identify and encode KAP. The invention also provides expresson vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KAP.Type: GrantFiled: December 4, 2001Date of Patent: April 18, 2006Assignee: Incyte CorporationInventors: Henry Yue, Li Ding, Preeti G. Lal, Jennifer A. Griffin, Rajagopal Gururajan, Mariah R. Baughn, Craig H. Ison, Jayalaxmi Ramkumar, Catherine M. Tribouley, Anita Swarnakar, Neil Burford, Olga Bandman, Michael Thornton, Farrah A. Khan, Narinder K. Chawla, Danniel B. Nguyen, Vicki S. Elliott, Yuming Xu, Yan Lu, April J. A. Hafalia, Monique G. Yao, Ameena R. Gandhi, Chandra S. Arvizu, Ian J. Forsythe
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Patent number: 6962799Abstract: The invention provides human microtubule-associated proteins and tubulins (MICAPTUB) and polynucleotides which identify and encode MICAPTUB. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MICAPTUB.Type: GrantFiled: August 20, 2001Date of Patent: November 8, 2005Assignee: Incyte CorporationInventors: Henry Yue, Danniel B. Nguyen, Catherine M. Tribouley, Olga Bandman, Y. Tom Tang, Preeti G. Lal, Narinder K. Chawla, Jennifer L. Policky
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Patent number: 6927056Abstract: The invention provides a human cysteine proteases and polynucleotides which encode those proteases. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists, as well as methods for diagnosing, treating, or preventing disorders associated with aberrant expression of cysteine proteases.Type: GrantFiled: September 6, 2001Date of Patent: August 9, 2005Assignee: Incyte CorporationInventors: Stephen Todd, Angelo M. Delegeane, Ameena R. Gandhi, Danniel B. Nguyen, April J. A. Hafalia, Liam Kearney, Yan Lu, Ernestine A. Lee, Narinder K. Chawla, Debopriya Das, Chandra S. Arvizu, Monique G. Yao, Deborah A. Kallick, Vicki S. Elliott, Li Ding, Henry Yue, Roopa M. Reddy, Dyung Aina M. Lu, Jayalaxmi Ramkumar, Junming Yang, Catherine M. Tribouley, Neil Burford, Mariah R. Baughn, Preeti G. Lal, Mark L. Borowsky, Farrah A. Khan, Rajagopal Gururajan, Y. Tom Tang, Janice K. Au-Young, Bridget A. Warren, Roberto Hernandez, Brendan M. Duggan
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Publication number: 20040265807Abstract: The invention provides human enzymes (NZMS) and polynucleotides which identify and encode NZMS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NZMS.Type: ApplicationFiled: March 8, 2004Publication date: December 30, 2004Inventors: Madhusudan M Sanjanwala, Yan Lu, Ernestine A Lee, April J A Hafalia, Bridget A Warren, Mariah R Baughn, Y Tom Tang, Henry Yue, Monique G Yao, Sally Lee, Michael B Thornton, Narinder K Chawla, Yuming Xu, Uyen K Tran, Preeti G Lal, Dyung Aina M Lu, Anita Swarnakar, Huijun Z Ring, Karen A Jones
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Publication number: 20040254350Abstract: various embodiments of the invention provide human immune response associated proteins (TRAP) and polynucleotides which identify and encode IRAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of IRAP.Type: ApplicationFiled: March 19, 2004Publication date: December 16, 2004Inventors: Anne Ho, Mariah R Baughn, Shanya D Becha, Neil Burford, Vicki S Elliott, Brooke M Emerling, Ian J Forsythe, Ann E Gorvad, Jennifer A Griffin, April JA Hafalia, Cynthia D Honchell, John D Burrill, Julie J Blake, Preeti G Lal, Ernestine A Lee, Joseph P Marquis, Patricia M Lehr-Mason, Sally Lee, William W Sprague, Anita Swarnakar, Y Tom Tang, Bao Tran, Uyen K Tran, Umesh G Bhatia, Narinder K Chawla, Bridget A Warren, Wenjin Zheng, Yuming Xu, Henry Yue
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Publication number: 20040253588Abstract: The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.Type: ApplicationFiled: August 28, 2003Publication date: December 16, 2004Inventors: Mariah R. Baughn, Christopher M. Bruns, Debopriya Das, Li Ding, Vicki S. Elliott, Ameena R. Gandhi, April J. A. Hafalia, Liam Kearney, Farrah A Khan, Preeti G. Lal, Ernestine A. Lee, Dyung Aina M. Lu, Yan Lu, Danniel B. Nguyen, Chandra S. Arvizu, Jayalaxmi Ramkumar, Huijun Z. Ring, Madhusudan M. Sanjanwala, Y.Tom Tang, Kavitha Tangavelu, Michael B. Thornton, Catherine M. Tribouley, Narinder K. Chawla, Yuming Xu, Junming Yang, Monique G. Yao, Henry Yue