Patents by Inventor Preeti G. Lal

Preeti G. Lal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8569445
    Abstract: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: October 29, 2013
    Assignee: Incyte Corporation
    Inventors: Henry Yue, Monique G. Yao, Ameena R. Gandhi, Mariah R. Baughn, Anita Swarnakar, Narinder Chawla, Madhusudan M. Sanjanwala, Michael Thorton, Vicki S. Elliott, Yan Lu, Kimberly J. Gietzen, Neil Burford, Li Ding, April J. A. Hafalia, Y. Tom Tang, Olga Bandman, Bridget A. Warren, Cynthia D. Honchell, Dyung Aina M. Lu, Kavitha Thangavelu, Sally Lee, Yuming Xu, Junming Yang, Preeti G. Lal, Bao Tran, Craig H. Ison, Brendan M. Duggan, Stephanie K. Sapperstein
  • Publication number: 20130243781
    Abstract: The invention provides cDNAs which encodes a signal peptide-containing proteins. It also provides for the use of a cDNA, protein, and antibody in the diagnosis, prognosis, treatment and evaluation of therapies for cancer. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.
    Type: Application
    Filed: February 8, 2013
    Publication date: September 19, 2013
    Applicant: Incyte Corporation
    Inventors: Preeti G. LAL, Janice Au-Young, Roopa Reddy, Lynn E. Murry, Preete Mathur
  • Publication number: 20130190250
    Abstract: The invention provides a human signal peptide-containing proteins (SIGP) and polynucleotides which identify and encode SIGP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of SIGP.
    Type: Application
    Filed: September 14, 2012
    Publication date: July 25, 2013
    Inventors: Preeti G. Lal, Jennifer L. Jackson, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn, Susan K. Sather, Purvi Shah
  • Patent number: 8206947
    Abstract: The invention provides human transmembrane proteins (HTMPN) and polynucleotides which identify and encode HTMPN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HTMPN.
    Type: Grant
    Filed: November 8, 2006
    Date of Patent: June 26, 2012
    Assignee: Incyte Corporation
    Inventors: Y. Tom Tang, Preeti G. Lal, Jennifer L. Jackson, Henry Yue, Karl J. Guegler, Neil C. Corley, Olga Bandman, Chandra S. Arvizu, Gina A. Gorgone Simone, Matthew R. Kaser, Mariah R. Baughn, Janice K. Au-Young
  • Patent number: 8153398
    Abstract: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: April 10, 2012
    Assignee: Incyte Corporation
    Inventors: Preeti G. Lal, Y. Tom Tang, Gina A. Gorgone Simone, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn, Ingrid E. Akerblom, Janice K. Au-Young, Henry Yue, Chandra S. Arvizu, Roopa M. Reddy, Jennifer L. Hillman, Olga Bandman
  • Patent number: 8148067
    Abstract: The invention presents a method of diagnosing or monitoring the status of systemic lupus erythematosus (SLE) in a subject or patient comprising detecting the expression of all genes of a diagnostic set in the subject or patient wherein the diagnostic set comprises two or more genes having expression correlated with the classification or status of SLE; and diagnosing or monitoring the status of SLE in the subject or patient by applying at least one statistical method to the expression of the genes of the diagnostic set.
    Type: Grant
    Filed: November 9, 2007
    Date of Patent: April 3, 2012
    Assignee: Xdx, Inc.
    Inventors: Preeti G. Lal, Gavin E. Williams, Kirk E. Fry, Jingtao Sun, Russell L. Dedrick
  • Publication number: 20100099617
    Abstract: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
    Type: Application
    Filed: September 14, 2009
    Publication date: April 22, 2010
    Inventors: Henry Yue, Monique G. Yao, Ameena R. Gandhi, Mariah R. Baughn, Anita Swarnakar, Narinder K. Chawla, Madhusudan M. Sanjanwala, Michael B. Thornton, Vicki S. Elliott, Yan Lu, Kimberly J. Gietzen, Neil Burford, Li Ding, April J. A. Hafalia, Y. Tom Tang, Olga Bandman, Bridget A. Warren, Cynthia D. Honchell, Dyung Aina M. Lu, Kavitha Thangavelu, Sally Lee, Yuming Xu, Junming Yang, Preeti G. Lal, Bao Tran, Craig H. Ison, Brendan M. Duggan, Stephanie K. Sapperstein
  • Publication number: 20100092989
    Abstract: Described herein is a system for monitoring gene expression for diagnosing and monitoring inflammation disorders, and for monitoring gene expression in inflammation disorders in response to a particular drug treatment regimen. This system for detecting nucleic acid expression in a body fluid uses an isolated polynucleotide to detect expression of a nucleic acid comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 5; SEQ ID NO:11; SEQ ID NO:17; and SEQ ID NO: 23. These nucleic acids are differentially expressed in body fluid in an individual with a disease criterion for a disease as listed in Table 1 as compared to an individual without the disease criterion.
    Type: Application
    Filed: December 10, 2009
    Publication date: April 15, 2010
    Applicant: XDx, Inc.
    Inventors: Jay WOHLGEMUTH, Darren Tayama, Dirk Walther, Preeti G. Lal
  • Patent number: 7645575
    Abstract: Described herein is a system for monitoring gene expression for diagnosing and monitoring inflammation disorders, and for monitoring gene expression in inflammation disorders in response to a particular drug treatment regimen. This system for detecting nucleic acid expression in a body fluid uses an isolated polynucleotide to detect expression of a nucleic acid comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 5; SEQ ID NO:11; SEQ ID NO:17; and SEQ ID NO: 23. These nucleic acids are differentially expressed in body fluid in an individual with a disease criterion for a disease as listed in Table 1 as compared to an individual without the disease criterion.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: January 12, 2010
    Assignee: XDX, Inc.
    Inventors: Jay Wohlgemuth, Darren Tayama, Dirk Walther, Preeti G. Lal
  • Publication number: 20090298060
    Abstract: The invention presents a method of diagnosing or monitoring the status of systemic lupus erythematosus (SLE) in a subject or patient comprising detecting the expression of all genes of a diagnostic set in the subject or patient wherein the diagnostic set comprises two or more genes having expression correlated with the classification or status of SLE; and diagnosing or monitoring the status of SLE in the subject or patient by applying at least one statistical method to the expression of the genes of the diagnostic set.
    Type: Application
    Filed: November 9, 2007
    Publication date: December 3, 2009
    Applicant: XDX, Inc.
    Inventors: Preeti G. LAL, Gavin E. Williams, Kirk E. Fry, Jingtao Sun, Russell L. Dedrick
  • Patent number: 7608704
    Abstract: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: October 27, 2009
    Assignee: Incyte Corporation
    Inventors: Henry Yue, Monique G. Yao, Ameena R. Gandhi, Mariah R. Baughn, Anita Swarnakar, Narinder Chawla, Madhusudan M. Sanjanwala, Michael Thorton, Vicki S. Elliott, Yan Lu, Kimberly J. Gietzen, Neil Burford, Li Ding, April J. A. Hafalia, Y. Tom Tang, Olga Bandman, Bridget A. Warren, Cynthia D. Honchell, Dyung Aina M. Lu, Kavitha Thangavelu, Sally Lee, Yuming Xu, Junming Yang, Preeti G. Lal, Bao Tran, Craig H. Ison, Brendan M. Duggan, Stephanie K. Sapperstein
  • Publication number: 20080241158
    Abstract: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
    Type: Application
    Filed: August 29, 2007
    Publication date: October 2, 2008
    Inventors: Preeti G. Lal, Richard C. Graul, April J.A. Hafalia, Narinder K. Chawla, Michael B. Thornton, Danniel B. Nguyen, Yan Lu, Ameena R. Gandhi, Chandra S. Arvizu, Deborah A. Kallick, Mariah R. Baughn, Jayalaxmi Ramkumar, Catherine M. Tribouley, Ernestine A. Lee, Li Ding, Neil Burford, Monique G. Yao, Junming Yang, Jennifer A. Griffin
  • Publication number: 20080181895
    Abstract: The invention provides cDNAs which encodes a signal peptide-containing proteins. It also provides for the use of a cDNA, protein, and antibody in the diagnosis, prognosis, treatment and evaluation of therapies for cancer. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.
    Type: Application
    Filed: November 6, 2007
    Publication date: July 31, 2008
    Inventors: Preeti G. Lal, Janice Au-Young, Roopa Reddy, Lynn E. Murry, Preete Mathur
  • Patent number: 7321023
    Abstract: The invention provides cDNAs which encodes a signal peptide-containing proteins. It also provides for the use of a cDNA, protein, and antibody in the diagnosis, prognosis, treatment and evaluation of therapies for cancer. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.
    Type: Grant
    Filed: October 1, 2001
    Date of Patent: January 22, 2008
    Assignee: Incyte Corporation
    Inventors: Preeti G. Lal, Janice Au-Young, Roopa Reddy, Lynn E. Murry, Preete Mathur
  • Patent number: 7029897
    Abstract: The invention provides human kinases and phosphatases (KAP) and polnucleotides which identify and encode KAP. The invention also provides expresson vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KAP.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: April 18, 2006
    Assignee: Incyte Corporation
    Inventors: Henry Yue, Li Ding, Preeti G. Lal, Jennifer A. Griffin, Rajagopal Gururajan, Mariah R. Baughn, Craig H. Ison, Jayalaxmi Ramkumar, Catherine M. Tribouley, Anita Swarnakar, Neil Burford, Olga Bandman, Michael Thornton, Farrah A. Khan, Narinder K. Chawla, Danniel B. Nguyen, Vicki S. Elliott, Yuming Xu, Yan Lu, April J. A. Hafalia, Monique G. Yao, Ameena R. Gandhi, Chandra S. Arvizu, Ian J. Forsythe
  • Patent number: 6962799
    Abstract: The invention provides human microtubule-associated proteins and tubulins (MICAPTUB) and polynucleotides which identify and encode MICAPTUB. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MICAPTUB.
    Type: Grant
    Filed: August 20, 2001
    Date of Patent: November 8, 2005
    Assignee: Incyte Corporation
    Inventors: Henry Yue, Danniel B. Nguyen, Catherine M. Tribouley, Olga Bandman, Y. Tom Tang, Preeti G. Lal, Narinder K. Chawla, Jennifer L. Policky
  • Patent number: 6927056
    Abstract: The invention provides a human cysteine proteases and polynucleotides which encode those proteases. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists, as well as methods for diagnosing, treating, or preventing disorders associated with aberrant expression of cysteine proteases.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: August 9, 2005
    Assignee: Incyte Corporation
    Inventors: Stephen Todd, Angelo M. Delegeane, Ameena R. Gandhi, Danniel B. Nguyen, April J. A. Hafalia, Liam Kearney, Yan Lu, Ernestine A. Lee, Narinder K. Chawla, Debopriya Das, Chandra S. Arvizu, Monique G. Yao, Deborah A. Kallick, Vicki S. Elliott, Li Ding, Henry Yue, Roopa M. Reddy, Dyung Aina M. Lu, Jayalaxmi Ramkumar, Junming Yang, Catherine M. Tribouley, Neil Burford, Mariah R. Baughn, Preeti G. Lal, Mark L. Borowsky, Farrah A. Khan, Rajagopal Gururajan, Y. Tom Tang, Janice K. Au-Young, Bridget A. Warren, Roberto Hernandez, Brendan M. Duggan
  • Publication number: 20040265807
    Abstract: The invention provides human enzymes (NZMS) and polynucleotides which identify and encode NZMS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NZMS.
    Type: Application
    Filed: March 8, 2004
    Publication date: December 30, 2004
    Inventors: Madhusudan M Sanjanwala, Yan Lu, Ernestine A Lee, April J A Hafalia, Bridget A Warren, Mariah R Baughn, Y Tom Tang, Henry Yue, Monique G Yao, Sally Lee, Michael B Thornton, Narinder K Chawla, Yuming Xu, Uyen K Tran, Preeti G Lal, Dyung Aina M Lu, Anita Swarnakar, Huijun Z Ring, Karen A Jones
  • Publication number: 20040253588
    Abstract: The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.
    Type: Application
    Filed: August 28, 2003
    Publication date: December 16, 2004
    Inventors: Mariah R. Baughn, Christopher M. Bruns, Debopriya Das, Li Ding, Vicki S. Elliott, Ameena R. Gandhi, April J. A. Hafalia, Liam Kearney, Farrah A Khan, Preeti G. Lal, Ernestine A. Lee, Dyung Aina M. Lu, Yan Lu, Danniel B. Nguyen, Chandra S. Arvizu, Jayalaxmi Ramkumar, Huijun Z. Ring, Madhusudan M. Sanjanwala, Y.Tom Tang, Kavitha Tangavelu, Michael B. Thornton, Catherine M. Tribouley, Narinder K. Chawla, Yuming Xu, Junming Yang, Monique G. Yao, Henry Yue
  • Publication number: 20040254350
    Abstract: various embodiments of the invention provide human immune response associated proteins (TRAP) and polynucleotides which identify and encode IRAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of IRAP.
    Type: Application
    Filed: March 19, 2004
    Publication date: December 16, 2004
    Inventors: Anne Ho, Mariah R Baughn, Shanya D Becha, Neil Burford, Vicki S Elliott, Brooke M Emerling, Ian J Forsythe, Ann E Gorvad, Jennifer A Griffin, April JA Hafalia, Cynthia D Honchell, John D Burrill, Julie J Blake, Preeti G Lal, Ernestine A Lee, Joseph P Marquis, Patricia M Lehr-Mason, Sally Lee, William W Sprague, Anita Swarnakar, Y Tom Tang, Bao Tran, Uyen K Tran, Umesh G Bhatia, Narinder K Chawla, Bridget A Warren, Wenjin Zheng, Yuming Xu, Henry Yue