Patents by Inventor Prem Prakash
Prem Prakash has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230248742Abstract: Stable pharmaceutical compositions are provided, comprising a pharmaceutically effective amount of testosterone or a pharmaceutically acceptable ester thereof, a pharmaceutically acceptable oil vehicle, and a stabilizing amount of benzyl alcohol, for example, about 1% to 3% weight/volume of benzyl alcohol. The present invention also provides a process for stabilizing testosterone-containing pharmaceutical compositions by ageing them at a temperature of about 20° C. to about 60° C. for at least 48 hours, e.g., prior to secondary packing and labeling. These compositions were stable over the shelf life of the product, without exhibiting crystal formation, even upon storing at temperatures of about 2° C. to about 8° C. Other aspects of the invention relate to methods for making such pharmaceutical compositions and methods of using such pharmaceutical compositions for hormone replacement therapy, e.g.Type: ApplicationFiled: April 12, 2023Publication date: August 10, 2023Applicant: SLAYBACK PHARMA LLCInventors: Umangi K. SONI, Prem Prakash SINGH, Hanimi Reddy BAPATU, Praveen Kumar SUBBAPPA, Ajay Kumar SINGH
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Patent number: 11642355Abstract: The present invention provides stable pharmaceutical compositions, comprising a pharmaceutically effective amount of testosterone or a pharmaceutically acceptable ester thereof, a pharmaceutically acceptable oil vehicle, and a stabilizing amount of benzyl alcohol, for example, about 1% to 3% weight/volume of benzyl alcohol. The present invention also provides a process for stabilizing testosterone-containing pharmaceutical compositions by ageing them at a temperature of about 20° C. to about 60° C. for at least 48 hours, e.g., prior to secondary packing and labeling. These compositions were stable over the shelf life of the product, without exhibiting crystal formation, even upon storing at temperatures of about 2° C. to about 8° C. Other aspects of the invention relate to methods for making such pharmaceutical compositions, as well as methods of using such pharmaceutical compositions for hormone replacement therapy, e.g.Type: GrantFiled: March 16, 2022Date of Patent: May 9, 2023Assignee: SLAYBACK PHARMA LLCInventors: Umangi K. Soni, Prem Prakash Singh, Hanimi Reddy Bapatu, Praveen Kumar Subbappa, Ajay Kumar Singh
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Patent number: 11591456Abstract: Polymer blends, methods of making the polymer blends, and articles of manufacture that include the polymer blends are described. A polymer blend can include a high density polyethylene (HDPE) polymer and a random block copolymer. The random block copolymer can include two different saturated alkane blocks between aromatic blocks (e.g., two styrenic blocks).Type: GrantFiled: April 24, 2019Date of Patent: February 28, 2023Assignee: SABIC GLOBAL TECHNOLOGIES B.V.Inventors: Anantharaman Dhanabalan, Maria Soliman, Anirban Ganguly, Sangita Nandi, Prem Prakash Pathak, Kummetha Raghunatha Reddy, Abderrahman Meddad, Sadasivam Gopalakrishnan
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Publication number: 20220202830Abstract: The present invention provides stable pharmaceutical compositions, comprising a pharmaceutically effective amount of testosterone or a pharmaceutically acceptable ester thereof, a pharmaceutically acceptable oil vehicle, and a stabilizing amount of benzyl alcohol, for example, about 1% to 3% weight/volume of benzyl alcohol. The present invention also provides a process for stabilizing testosterone-containing pharmaceutical compositions by ageing them at a temperature of about 20° C. to about 60° C. for at least 48 hours, e.g., prior to secondary packing and labeling. These compositions were stable over the shelf life of the product, without exhibiting crystal formation, even upon storing at temperatures of about 2° C. to about 8° C. Other aspects of the invention relate to methods for making such pharmaceutical compositions, as well as methods of using such pharmaceutical compositions for hormone replacement therapy, e.g.Type: ApplicationFiled: March 16, 2022Publication date: June 30, 2022Applicant: SLAYBACK PHARMA LLCInventors: Umangi K. SONI, Prem Prakash SINGH, Hanimi Reddy BAPATU, Praveen Kumar SUBBAPPA, Ajay Kumar SINGH
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Patent number: 11311554Abstract: The present invention provides stable pharmaceutical compositions, comprising a pharmaceutically effective amount of testosterone or a pharmaceutically acceptable ester thereof, a pharmaceutically acceptable oil vehicle, and a stabilizing amount of benzyl alcohol, for example, about 1% to 3% weight/volume of benzyl alcohol. The present invention also provides a process for stabilizing testosterone-containing pharmaceutical compositions by ageing them at a temperature of about 20° C. to about 60° C. for at least 48 hours, e.g., prior to secondary packing and labeling. These compositions were stable over the shelf life of the product, without exhibiting crystal formation, even upon storing at temperatures of about 2° C. to about 8° C. Other aspects of the invention relate to methods for making such pharmaceutical compositions, and methods of using such pharmaceutical compositions for hormone replacement therapy, e.g.Type: GrantFiled: March 25, 2019Date of Patent: April 26, 2022Assignee: SLAYBACK PHARMA LLCInventors: Umangi K. Soni, Prem Prakash Singh, Hanimi Reddy Bapatu, Praveen Kumar Subbappa, Ajay Kumar Singh
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Publication number: 20210147659Abstract: Polymer blends, methods of making the polymer blends, and articles of manufacture that include the polymer blends are described. A polymer blend can include a high density polyethylene (HDPE) polymer and a random block copolymer. The random block copolymer can include two different saturated alkane blocks between aromatic blocks (e.g., two styrenic blocks).Type: ApplicationFiled: April 24, 2019Publication date: May 20, 2021Inventors: Anantharaman DHANABALAN, Maria SOLIMAN, Anirban GANGULY, Sangita NANDI, Prem Prakash PATHAK, Kummetha Raghunatha REDDY, Abderrahman MEDDAD, Sadasivam GOPALAKRISHNAN
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Publication number: 20200303063Abstract: In some embodiments, a management system is configured to dynamically generate and/or adjust a step-by-step care regimen. The care regimen, or step-by-step plan, is broken down by the system into specific actions presented to a patient at specific times with tailored guidance on how to achieve the best effect of each step. The system can be configured to build tailored care plans that span contemplation phases, preparation phases, recovery phases, and long term care phases. In further embodiments, over the treatment life cycle, the system facilitates patient care compliance, planning and education, among other options. In other embodiments, the system is configured to dynamically capture and develop implicit relationship information on a patient's care journey, and augment care options for respective patients responsive to identifying implicit connections developed within the context of the patient's care journey (e.g., specified by patient provider, procedure, physician, comorbidities, etc.).Type: ApplicationFiled: March 20, 2020Publication date: September 24, 2020Applicant: Health Innovators IncorporatedInventors: Prem Prakash Sharma, Christine Lih Hsieh, Stuart Martin Kirchner, Elizabeth Kathryn Bisio, Douglas Neil Kurth, Chien-Min Lu
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Publication number: 20200257523Abstract: According to a computer-implemented method, sections of an application program instruction set are marked with tags to associate the sections of the application program instruction set with different application features. A change made to a section of the application program instruction set is detected. Based on a tag, the change to the section of the application program instruction set is associated with a change to a respective application feature.Type: ApplicationFiled: February 11, 2019Publication date: August 13, 2020Inventors: Bharat B. Purohit, Prem Prakash, Ratnalikar Sarang Deepak, Arun Ramakrishnan
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Publication number: 20190307772Abstract: The present invention provides stable pharmaceutical compositions, comprising a pharmaceutically effective amount of testosterone or a pharmaceutically acceptable ester thereof, a pharmaceutically acceptable oil vehicle, and a stabilizing amount of benzyl alcohol, for example, about 1% to 3% weight/volume of benzyl alcohol. The present invention also provides a process for stabilizing testosterone-containing pharmaceutical compositions by ageing them at a temperature of about 20° C. to about 60° C. for at least 48 hours, e.g., prior to secondary packing and labeling. These compositions were stable over the shelf life of the product, without exhibiting crystal formation, even upon storing at temperatures of about 2° C. to about 8° C. Other aspects of the invention relate to methods for making such pharmaceutical compositions, and methods of using such pharmaceutical compositions for hormone replacement therapy, e.g.Type: ApplicationFiled: March 25, 2019Publication date: October 10, 2019Applicant: SLAYBACK PHARMA LLCInventors: Umangi K. SONI, Prem Prakash SINGH, Hanimi Reddy BAPATU, Praveen Kumar SUBBAPPA, Ajay Kumar SINGH
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Patent number: 9687480Abstract: Chiral 1-(4-methylphenylmethyl)-5-oxo-{N-[(3-t-butoxycarbonyl-aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion. The present invention provides chiral (2S)-1-(4-methylphenylmethyl)-5-oxo-(3S)-{N-[(3-t-butoxycarbonyl aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide, and (2S)-1-(4-methylphenylmethyl)-5-oxo-(3R)-{N-[(3-t-butoxycarbonyl amino methyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide of formula 6 and 7 respectively. The present invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors. The present invention provides a process for preparation of chiral carboxamides of formula 6 and 7 using the process which has advantage to avoid any racemization at the a-carboxylic center, during N-alkylation. The reagent LiHMDS is used at low temperatures to furnish methyl N-(p-methylphenylmethyl)1pyroglutamate in good chiral purity.Type: GrantFiled: November 5, 2015Date of Patent: June 27, 2017Assignee: Council of Scientific & Industrial ResearchInventors: Dinesh Kumar Dikshit, Madhu Dikshit, Tanveer Irshad Siddiqui, Anil Kumar, Rabi Sankar Bhatta, Girish Kumar Jain, Manoj Kumar Barthwal, Ankita Misra, Vivek Khanna, Prem Prakash, Manish Jain, Vishal Singh, Varsha Gupta, Anil Kumar Dwivedi
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Publication number: 20160143896Abstract: Chiral 1-(4-methylphenylmethyl)-5-oxo-{N-[(3-t-butoxycarbonyl-aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion. The present invention provides chiral (2S)-1-(4-methyl-phenylmethyl)-5-oxo-(3S)-{N-[(3-t-butoxycarbonyl aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide, and (2S)-1-(4-methylphenylmethyl)-5-oxo-(3R)-{N-[(3-t-butoxycarbonyl amino methyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide of formula 6 and 7 respectively. The present invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors. The present invention provides a process for preparation of chiral carboxamides of formula 6 and 7 using the process which has advantage to avoid any racemization at the a-carboxylic center, during N-alkylation. The reagent LiHMDS is used at low temperatures to furnish methyl N-(p-methylphenylmethyl)1pyroglutamate in good chiral purity.Type: ApplicationFiled: November 5, 2015Publication date: May 26, 2016Inventors: Dinesh Kumar DIKSHIT, Madhu DIKSHIT, Tanveer Irshad SIDDIQUI, Anil KUMAR, Rabi Sankar BHATTA, Girish Kumar JAIN, Manoj Kumar BARTHWAL, Ankita MISRA, Vivek KHANNA, Prem PRAKASH, Manish JAIN, Vishal SINGH, Varsha GUPTA, Anil Kumar DWIVEDI
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Patent number: 9206155Abstract: Chiral 1-(4-methylphenylmethyl)-5-oxo-{N-[(3-t-butoxycarbonyl-aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion The present invention provides chiral (2S)-1-(4-methyl-phenylmethyl)-5-oxo-(3S)—{N-[(3-t-butoxycarbonyl aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide, and (2S)-1-(4-methylphenylmethyl)-5-oxo-(3R)—{N-[(3-t-butoxycarbonyl amino methyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide of formula 6 and 7 respectively. The present invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors. The present invention provides a process for preparation of chiral carboxamides of formula 6 and 7 using the process which has advantage to avoid any racemization at the a-carboxylic center, during N-alkylation. The reagent LiHMDS is used at low temperatures to furnish methyl N-(p methylphenylmethyl)lpyroglutamate in good chiral purity.Type: GrantFiled: January 12, 2012Date of Patent: December 8, 2015Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Dinesh Kumar Dikshit, Madhu Dikshit, Tanveer Irshad Siddiqui, Anil Kumar, Rabi Sankar Bhatta, Girish Kumar Jain, Manoj Kumar Barthwal, Ankita Misra, Vivek Khanna, Prem Prakash, Manish Jain, Vishal Singh, Varsha Gupta, Anil Kumar Dwivedi
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Publication number: 20130338193Abstract: Chiral 1-(4-methylphenylmethyl)-5-oxo-{N-[(3-t-butoxycarbonyl-aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion The present invention provides chiral (2S)-1-(4-methyl-phenylmethyl)-5-oxo-(3S)-{N-[(3-t butoxycarbonyl aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide, and (2S)-1-(4-methylphenylmethyl)-5-oxo-(3R)-{N-[(3-t-butoxycarbonyl amino methyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide of formula 6 and 7 respectively. The present invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors. The present invention provides a process for preparation of chiral carboxamides of formula 6 and 7 using the process which has advantage to avoid any racemization at the a-carboxylic center, during N-alkylation. The reagent LiHMDS is used at low temperatures to furnish methyl N-(p methylphenylmethyl)lpyroglutamate in good chiral purity.Type: ApplicationFiled: January 12, 2012Publication date: December 19, 2013Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Dinesh Kumar Dikshit, Madhu Dikshit, Tanveer Irshad Siddiqui, Anil Kumar, Rabi Sankar Bhata, Girish Kumar Jain, Manoj Kumar Barthwal, Ankita Misra, Vivek Khanna, Prem Prakash, Manish Jain, Vishal Singh, Varsha Gupta, Anil Kumar Dwivedi
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Publication number: 20130311285Abstract: Systems and methods for responding to a search query from a user are presented. In responding to a search query from a user, the user is presented with a search results page. The search results page includes both search results (relevant to the search query) and one or more advertisements. At least one of the advertisements is a specially configured advertisement that includes a corresponding app. Execution of the app is initiated through a user-actionable control in the advertisement. Unlike other advertisements that cause navigation to an advertisers landing page, the corresponding app executes within the context of the browser view/search results page. The corresponding app may be designed so that a transaction may be completed through its execution (the particular transaction depending upon the design of the app.Type: ApplicationFiled: May 18, 2012Publication date: November 21, 2013Applicant: MICROSOFT CORPORATIONInventors: Sameer Abrol, Prem Prakash, Sriram K. Parameswar, Vageesh Banga
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Patent number: 5431869Abstract: This invention relates to a process for the preparation of polycrystalline silicon ingots by providing a first layer of coating on the inside walls of a mold with a slurry of silicon nitride powder in an organic binder dissolved in a solvent; charging the said coated mold with silicon pieces along with calcium chloride or/and calcium fluoride; heating the mold to a temperature in the range of 1420.degree.-1500.degree. C. so as to melt the silicon, by keeping the mold inside the furnace; bringing down the temperature of the mold to a temperature 5.degree.-10.degree. C. above the melting point of silicon; withdrawing the mold containing the melt downwardly and slowly from the hot zone of the furnace so that the solidification of the melt starts from the bottom of the mold and proceeds towards the top as the withdrawal continues till all the melt solidifies; cooling the mold to the room temperature under inert atmosphere and removing the polycrystalline silicon ingot from the mold.Type: GrantFiled: January 12, 1993Date of Patent: July 11, 1995Assignee: Council of Scientific & Industrial ResearchInventors: Singh P. Kumar, Prem Prakash
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Patent number: 4068105Abstract: Apparatus for transmitting signal information between central and remote stations in a central station system such as a central station alarm system. The transmission apparatus can continue to transmit information despite the occurrence of any of several types of fault conditions in the transmission line. Apparatus can be provided for detecting various transmission line fault conditions, indicating the nature of those fault conditions, and modifying the transmission apparatus to compensate for those fault conditions.Type: GrantFiled: May 28, 1976Date of Patent: January 10, 1978Assignee: American District Telegraph CompanyInventors: Prem Prakash Jain, James John Bernitt