Patents by Inventor Prem Shankar Subramaniam

Prem Shankar Subramaniam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid interferon tau/alpha polypeptides, their recombinant production, and methods using them
    Patent number: 5939286
    Abstract: The present invention describes hybrid interferon fusion polypeptides formed of a first segment that contains the N-terminal amino acid sequence of an interferon-tau polypeptide, and a second segment that contains the C-terminal amino acid sequence of a non-tau interferon type I polypeptide. The two segments are joined in the region of a mature interferon polypeptide between about residues 8 and 37. Also described are nucleic acid sequences encoding such interferon fusion polypeptides, expression vectors containing such sequences, and therapeutic applications of the interferon fusion polypeptides. The therapeutic applications include antiviral and anticellular proliferation applications. One advantage of the interferon fusion polypeptides of the present invention is that they do not have cytotoxic side-effects when used to treat cells.
    Type: Grant
    Filed: April 12, 1996
    Date of Patent: August 17, 1999
    Assignee: University of Florida
    Inventors: Howard Marcellus Johnson, Carol Hanlon Pontzer, Prem Shankar Subramaniam