Patents by Inventor Primož Knap

Primož Knap has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for stratification and early detection of advanced adenoma and/or colorectal cancer using DNA methylation markers
    Patent number: 12606872
    Abstract: The present disclosure provides for, among other things, methods and systems for detecting, diagnosing, predicting, monitoring, screening for, staging, and/or providing survival prognosis for advanced adenoma and/or colorectal cancer using DNA methylation markers. For example, described herein are DNA methylation markers that enable categorization and prognosis evaluation of advanced adenoma (AA) and/or colorectal cancer (CRC) patients with high accuracy from human biospecimens.
    Type: Grant
    Filed: January 12, 2023
    Date of Patent: April 21, 2026
    Assignee: Universal Diagnostics, S.A.
    Inventors: Pol Canal Noguer, Juan Carlos Higareda Almaraz, Francesco Mattia Mancuso, Kristi Kruusmaa, Alejandro Requena Bermejo, Marko Chersicola, Pablo Pérez Martínez, Pablo Antonio Camino Faillace, Primož Knap, Vivian Erklavec Zajec, Špela Zavodnik, Carme Nolla Colomer, Fernando Trincado Alonso
  • Methods and systems for identifying methylation biomarkers
    Patent number: 12467096
    Abstract: Described herein are various systems, methods, and apparatus for identifying biomarkers for detection of a disease or condition such as advanced adenoma, colorectal cancer, or other cancers. In certain embodiments, the present invention relates to methods and/or systems for identifying one or more biomarkers related to methylation status in cell-free deoxyribonucleic acid (DNA) of a human subject and/or detecting (e.g., screening for) cancer based on one or more known biomarkers (e.g., the identified biomarkers).
    Type: Grant
    Filed: September 21, 2020
    Date of Patent: November 11, 2025
    Assignee: Universal Diagnostics, S.A.
    Inventors: Marko Bitenc, Kristi Kruusmaa, Juan Martinez-Barea, Christian Hense, Pol Sola de los Santos, Pol Canal Noguer, Marko Chersicola, Primož Knap