Patents by Inventor Prior Trevor

Prior Trevor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant chimeric proteins deliverable across cellular membranes into cytosol of target cells
    Patent number: 5328984
    Abstract: Proteins that are impermeable and foreign to the eukaryotic cells can now be delivered across cellular membranes into the cytosol of target cells by making a chimeric protein having specific attributes. A method of making such chimeric proteins is disclosed. As an example, a chimeric protein PE-Bar with dual enzymatic activity has been made. The chimeric proteins can be used for cytotoxic, diagnostic or therapeutic purposes, such as for compensating the deficiency or defect of an enzyme or a protein which may be causative of a disease or an abnormality.
    Type: Grant
    Filed: March 4, 1991
    Date of Patent: July 12, 1994
    Assignee: The United States as represented by the Department of Health & Human Services
    Inventors: Ira H. Pastan, Prior Trevor, David J. Fitzgerald, Waldemar Debinski, Clay Siegall