Patents by Inventor Prisca Boisguerin

Prisca Boisguerin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides for use as cell-penetrating peptides
    Patent number: 11905338
    Abstract: The present invention relates to new peptides comprising an amino acid sequence LL-[X]n-LL, wherein X is selected from R, L and W, and n=10 to 12, and wherein [X]n comprises 4 R, 4 L and between 2 and 4 W, that may be used as cell-penetrating peptides. The present invention also relates to nanoparticles comprising a peptide of the invention and a cargo molecule and uses thereof.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: February 20, 2024
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE MONTPELLIER
    Inventors: Sébastien Deshayes, Karidia Konate, Eric Vives, Gudrun Aldrian, Prisca Boisguerin
  • PEPTIDES FOR USE AS CELL-PENETRATING PEPTIDES
    Publication number: 20210292364
    Abstract: The present invention relates to new peptides comprising an amino acid sequence LL-[X]n-LL, wherein X is selected from R, L and W, and n=10 to 12, and wherein [X]n comprises 4 R, 4 L and between 2 and 4 W, that may be used as cell-penetrating peptides. The present invention also relates to nanoparticles comprising a peptide of the invention and a cargo molecule and uses thereof.
    Type: Application
    Filed: July 16, 2019
    Publication date: September 23, 2021
    Inventors: SÉBASTIEN DESHAYES, KARIDIA KONATE, ERIC VIVES, GUDRUN ALDRIAN, PRISCA BOISGUERIN
  • Inhibitors of apoptosis and uses thereof
    Patent number: 9814758
    Abstract: The invention relates to fragments of the Death-Domain Associated protein (DAXX protein) and of the Fas-Associated Death Domain protein (FADD protein) that inhibit cell apoptosis, in particular cell apoptosis mediated by the Fas receptor. The invention also relates to derivatives of said anti-apoptotic fragments, conjugates comprising said fragments, pharmaceutical compositions comprising said fragments, and to the medical applications of said fragments, derivatives, conjugates, and pharmaceutical compositions thereof in the treatment or prevention of diseases and conditions associated with apoptosis.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: November 14, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE MONTPELLIER 2-SCIENCES ET TECHNIQUE, UNIVERSITE DE MONTPELLIER 1
    Inventors: Stéphanie Barrere, Joël Nargeot, Bernard Lebleu, Prisca Boisguerin, Christophe Piot
  • Therapy and kit for the prevention and treatment of cystic fibrosis
    Patent number: 9421239
    Abstract: A combination therapy and kit including an agent that inhibit the interaction between CAL and mutant CFTR proteins, in combination with a CFTR corrector, CFTR potentiator, mucolytic, anti-inflammatory agent or a combination thereof are provided as is a method for preventing or treating cystic fibrosis.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: August 23, 2016
    Assignee: TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguérin, Rudolf Volkmer, Lars Vouilleme
  • Combination therapy and kit for the prevention and treatment of cystic fibrosis
    Patent number: 9333235
    Abstract: A combination therapy and kit including an agent that inhibit the interaction between CAL and mutant CFTR proteins, in combination with a CFTR corrector, CFTR potentiator, mucolytic, anti-inflammatory agent or a combination thereof are provided as is a method for preventing or treating cystic fibrosis.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: May 10, 2016
    Assignee: Trustees of Dartmouth College
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguérin, Rudolf Volkmer, Lars Vouilleme
  • THERAPY AND KIT FOR THE PREVENTION AND TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20150250848
    Abstract: A combination therapy and kit including an agent that inhibit the interaction between CAL and mutant CFTR proteins, in combination with a CFTR corrector, CFTR potentiator, mucolytic, anti-inflammatory agent or a combination thereof are provided as is a method for preventing or treating cystic fibrosis.
    Type: Application
    Filed: May 22, 2015
    Publication date: September 10, 2015
    Applicant: Trustees of Dartmouth College
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguérin, Rudolf Volkmer, Lars Vouilleme
  • COMBINATION THERAPY AND KIT FOR THE PREVENTION AND TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20140100155
    Abstract: A combination therapy and kit including an agent that inhibit the interaction between CAL and mutant CFTR proteins, in combination with a CFTR corrector, CFTR potentiator, mucolytic, anti-inflammatory agent or a combination thereof are provided as is a method for preventing or treating cystic fibrosis.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 10, 2014
    Applicant: TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguérin, Rudolf Volkmer, Lars Vouilleme
  • Inhibitors of Apoptosis and Uses Thereof
    Publication number: 20130288979
    Abstract: The invention relates to fragments of the DAXX and FADD proteins that inhibit cell apoptosis, in particular cell apoptosis mediated by the Fas receptor. The invention also relates to derivatives of said anti-apoptotic fragments, conjugates comprising said fragments, pharmaceutical compositions comprising said fragments, and to the medical applications of said fragments, derivatives, conjugates, and pharmaceutical compositions thereof in the treatment or prevention of diseases and conditions associated with apoptosis.
    Type: Application
    Filed: November 17, 2011
    Publication date: October 31, 2013
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE DE MONTPELLIER 1, UNIVERSITE MONTPELLIER 2-SCIENCES ET TECHNIQUE
    Inventors: Stéphanie Barrere, Joël Nargeot, Bernard Lebleu, Prisca Boisguerin, Christophe Piot
  • Compositions and Methods for Inhibiting the Interaction between CFTR and CAL
    Publication number: 20110201544
    Abstract: The present invention features compositions and methods for increasing the cell surface expression of degradation-prone CFTR proteins and preventing or treating cystic fibrosis. The invention provides peptides and peptidomimetics that selectively inhibit the interaction between CAL and mutant CFTR proteins, thereby stabilizing the CFTR and facilitating transport of the same to the cell surface.
    Type: Application
    Filed: October 20, 2009
    Publication date: August 18, 2011
    Inventors: Dean Madden, Patrick R. Cushing, Prisca Boisguerin, Rudolf Volkmer, Lars Vouilleme