Patents by Inventor Priscilla L. Yang

Priscilla L. Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS FOR TREATING DENGUE VIRUS INFECTIONS AND OTHER INFECTIONS
    Publication number: 20210230101
    Abstract: Provided herein are compounds, pharmaceutical compositions, methods, and kits for treating viral infections (e.g., Dengue viral infections). In certain embodiments, compounds useful in the methods described herein are of Formula (I) or (II).
    Type: Application
    Filed: May 15, 2019
    Publication date: July 29, 2021
    Applicants: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Priscilla L. Yang, Nathanael S. Gray, Jaebong Jang, Jinhua Wang, Nicholas Paul Kwiatkowski, Wenlong Lian, Zhengnian Li
  • COMPOUNDS FOR TREATING DENGUE VIRUS INFECTION AND OTHER VIRAL INFECTIONS
    Publication number: 20200360381
    Abstract: The present disclosure provides antiviral (e.g., anti-Dengue virus) agents, such as compounds of Formula (I). Also provided are pharmaceutical compositions and kits of the compounds of Formula (I). Further provided are methods and uses of the antiviral agents (e.g., the compounds of Formula (I); and compounds K786-9739, S4105, C200-5340, G199-0398, C200-9144, S7337, S1633, and C066-4182, and derivatives thereof) for treating or preventing a viral infection (e.g., Dengue fever). The antiviral agents may inhibit the entry of a virus into a cell by, e.g., inhibiting the fusion between the envelope of the virus and the membrane of the cell.
    Type: Application
    Filed: May 15, 2018
    Publication date: November 19, 2020
    Applicants: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Priscilla L. Yang, Wenlong Lian, Nathanael S. Gray, Nicholas Paul Kwiatkowski, Jinhua Wang, Jaebong Jang
  • HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES
    Publication number: 20190292178
    Abstract: Novel antiviral compounds of Formulae (I)-(III) are provided: The inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by Flaviviridae virus (e.g., Dengue virus (DENV)), Kunjin virus, Japanese encephalitis virus, vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), human cytomegalovirus (HCMV), poliovirus, Junin virus, Ebola virus, Marburg virus (MARV), Lassa fever virus (LASV), Venezuelan equine encephalitis virus (VEEV), or Rift Valley Fever virus (RVFV).
    Type: Application
    Filed: January 26, 2018
    Publication date: September 26, 2019
    Applicants: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Nathanael S. Gray, Priscilla L. Yang, Qingsong Liu, Mélissanne de Wispelaere
  • HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES
    Publication number: 20180265507
    Abstract: Novel antiviral compounds of Formulae (I)-(III) are provided: The inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by Flaviviridae virus (e.g., Dengue virus (DENV)), Kunjin virus, Japanese encephalitis virus, vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), human cytomegalovirus (HCMV), poliovirus, Junin virus, Ebola virus, Marburg virus (MARV), Lassa fever virus (LASV), Venezuelan equine encephalitis virus (VEEV), or Rift Valley Fever virus (RVFV).
    Type: Application
    Filed: January 26, 2018
    Publication date: September 20, 2018
    Applicants: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Nathanael S. Gray, Priscilla L. Yang, Qingsong Liu, Mélissanne de Wispelaere