Patents by Inventor Priscilla Yang

Priscilla Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Degraders of hepatitis C virus NS3/4A protein
    Patent number: 12642856
    Abstract: Disclosed are bifunctional compounds (degraders) that target hepatitis C virus (HCV) NS3/4A for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat HCV infection and HCV-associated diseases or disorders.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: June 2, 2026
    Assignees: DANA-FARBER CANCER INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Nathanael S. Gray, Tinghu Zhang, Priscilla Yang, Melissanne De Wispelaere, Guangyan Du
  • DEGRADERS OF HEPATITIS C VIRUS NS3/4A PROTEIN
    Publication number: 20210338825
    Abstract: Disclosed are bifunctional compounds (degraders) that target hepatitis C virus (HCV) NS3/4A for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat HCV infection and HCV-associated diseases or disorders.
    Type: Application
    Filed: September 26, 2019
    Publication date: November 4, 2021
    Applicants: DANA-FARBER CANCER INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Nathanael S. Gray, Tinghu Zhang, Priscilla Yang, Melissanne De Wispelaere, Guangyan Du
  • Substituted heterocyclic compounds for treating or preventing viral infections
    Patent number: 10150742
    Abstract: Disclosed herein are pyrimidine compounds of formula I and formula II and methods for treating or preventing a viral infection, such as infections caused by dengue virus in a subject, comprising administering to said subject an effective amount of a pyrimidine compound of formula I or formula II.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 11, 2018
    Assignees: President and Fellows of Harvard College, Dana-Farber Cancer Institute, Inc.
    Inventors: Priscilla Yang, Nathanael S. Gray, Chandrasekhar Miduturu, Margaret J. Clark
  • Host targeted inhibitors of dengue virus and other viruses
    Patent number: 9879003
    Abstract: Novel antiviral compounds of Formulae (I)-(III) are provided: (I) (II) (III) The inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by Flaviviridae virus (e.g., Dengue virus (DENY)), Kunjin virus, Japanese encephalitis virus, vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), human cytomegalovirus (HCMV), poliovirus, Junin virus, Ebola virus, Marburg virus (MARV), Lassa fever virus (LASV), Venezuelan equine encephalitis virus (VEEV), or Rift Valley Fever virus (RVFV).
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 30, 2018
    Assignees: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Nathanael Gray, Priscilla Yang, Qingsong Liu, Mélissanne de Wispelaere
  • Substituted Heterocyclic Compounds for Treating or Preventing Viral Infections
    Publication number: 20160031826
    Abstract: Disclosed herein are pyrimidine compounds of formula I and formula II and methods for treating or preventing a viral infection, such as infections caused by dengue virus in a subject, comprising administering to said subject an effective amount of a pyrimidine compound of formula I or formula II.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Priscilla Yang, Nathanael S. Gray, Chandrasekhar Miduturu, Margaret J. Clark
  • HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES
    Publication number: 20150166532
    Abstract: Novel antiviral compounds of Formulae (I)-(III) are provided: (I) (II) (III) The inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by Flaviviridae virus (e.g., Dengue virus (DENY)), Kunjin virus, Japanese encephalitis virus, vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), human cytomegalovirus (HCMV), poliovirus, Junin virus, Ebola virus, Marburg virus (MARV), Lassa fever virus (LASV), Venezuelan equine encephalitis virus (VEEV), or Rift Valley Fever virus (RVFV).
    Type: Application
    Filed: March 15, 2013
    Publication date: June 18, 2015
    Inventors: Nathanael Gray, Priscilla Yang, Qingsong Liu, Mélissanne de Wispelaere