Patents by Inventor Priyadarshini Jaishankar

Priyadarshini Jaishankar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEIN-PROTEIN INTERACTION STABILIZERS
    Publication number: 20230142739
    Abstract: Provided herein, inter alia, are stabilizers of protein-protein interactions and methods of identifying and using the same.
    Type: Application
    Filed: April 2, 2021
    Publication date: May 11, 2023
    Inventors: Michelle R. Arkin, Lucas Brunsveld, Christian Ottmann, Adam R. Renslo, R. Jeffrey Neitz, Mengqi Zhong, Kenneth K. Hallenbeck, Priyadarshini Jaishankar, Shubhankar Dutta, John K. Morrow, Eline Sijbesma, Bente Aminhan Somsen, Galen Patrick Miley, Emira Josien Visser, Peter James Cossar, Madita Wolter, Thorsten Genski, Laura Mariana Levy, Torsten Hoffmann, Dimitrios Tzalis, Dario Valenti, Markella Konstantinidou
  • METHODS AND COMPOSITIONS FOR TREATING EPILEPSY
    Publication number: 20220226508
    Abstract: Provided, inter alia, are methods and compositions for treating epilepsy. In one aspect, provided herein is a method of selecting a compound for treating epilepsy, said method includes, contacting a test compound with 5-hydroxytryptamine-2B receptor (5-HT2B), and measuring the 5-HT2B agonistic activity of the test compound. In another aspect, provided herein is a method of treating an epilepsy in a subject in need thereof. The method includes administering to said subject an effective amount of a 5-HT2B specific receptor agonist.
    Type: Application
    Filed: May 28, 2020
    Publication date: July 21, 2022
    Inventors: Scott C. BARABAN, Aliesha L. GRIFFIN, Adam R. RENSLO, Priyadarshini JAISHANKAR
  • Beta-lactamase inhibitors, formulations, and uses thereof
    Patent number: 10864222
    Abstract: Provided herein are heterocyclic compounds and pharmaceutical formulations that can be used to treat bacterial infections. Also provided herein are methods of making and using the heterocyclic compounds and pharmaceutical formulations.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: December 15, 2020
    Assignees: UNIVERSITY OF SOUTH FLORIDA, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Yu Chen, Orville Antonio Pemberton, Adam Renslo, Priyadarshini Jaishankar
  • Compositions, methods of use, and methods of treatment
    Patent number: 10688080
    Abstract: The present disclosure provides compositions including a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: June 23, 2020
    Assignees: UNIVERSITY OF SOUTH FLORIDA, The Regents of the University of California
    Inventors: Yu Chen, Nicholas Joseph Torelli, Orville Antonio Pemberton, Xiujun Zhang, Adam Renslo, Kyle Defrees, Priyadarshini Jaishankar
  • Compositions, methods of use, and methods of treatment
    Patent number: 10604493
    Abstract: Embodiments of the present disclosure, in one aspect, relate to a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: March 31, 2020
    Assignees: University of South Florida, The Regents of the University of California
    Inventors: Yu Chen, Derek Nichols, Adam R. Renslo, Priyadarshini Jaishankar, Erica M. W. Lauterwasser
  • Beta-lactamase inhibitors, formulations, and uses thereof
    Patent number: 10543221
    Abstract: Provided herein are heterocyclic compounds and pharmaceutical formulations that can be used to treat bacterial infections. Also provided herein are methods of making and using the heterocyclic compounds and pharmaceutical formulations.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: January 28, 2020
    Assignees: University of South Florida, The Regents of the University of California
    Inventors: Yu Chen, Orville Antonio Pemberton, Adam Renslo, Priyadarshini Jaishankar
  • BETA-LACTAMASE INHIBITORS, FORMULATIONS, AND USES THEREOF
    Publication number: 20180360857
    Abstract: Provided herein are heterocyclic compounds and pharmaceutical formulations that can be used to treat bacterial infections. Also provided herein are methods of making and using the heterocyclic compounds and pharmaceutical formulations.
    Type: Application
    Filed: July 31, 2018
    Publication date: December 20, 2018
    Inventors: Yu Chen, Orville Antonio Pemberton, Adam Renslo, Priyadarshini Jaishankar
  • COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT
    Publication number: 20180333390
    Abstract: The present disclosure provides compositions including a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Application
    Filed: July 30, 2018
    Publication date: November 22, 2018
    Inventors: Yu Chen, Nicholas Joseph Torelli, Orville Antonio Pemberton, Xiujun Zhang, Adam Renslo, Kyle Defrees, Priyadarshini Jaishankar
  • Compositions, Methods of Use, And Methods of Treatment
    Publication number: 20170088524
    Abstract: Embodiments of the present disclosure, in one aspect, relate to a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Application
    Filed: November 8, 2016
    Publication date: March 30, 2017
    Inventors: Yu Chen, Derek Nichols, Adam R. Renslo, Priyadarshini Jaishankar, Erica M. W. Lauterwasser
  • Compositions, methods of use, and methods of treatment
    Patent number: 9556131
    Abstract: Embodiments of the present disclosure, in one aspect, relate to a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: January 31, 2017
    Assignees: UNIVERSITY OF SOUTH FLORIDA, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Yu Chen, Derek Nichols, Adam R. Renslo, Priyadarshini Jaishankar, Erica M. W. Lauterwasser
  • Dantagonists, methods of synthesis and methods of use
    Patent number: 9156840
    Abstract: Provided are D2 or D3 antagonist compounds and pharmaceutical compositions of formula I and pharmaceutically acceptable salts thereof, or isomers thereof, wherein R1, R2 and R3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D2 or D3 receptor from the compounds of the invention.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: October 13, 2015
    Assignee: ALTOS THERAPEUTICS, LLC
    Inventors: Gary W. Luehr, Arathi Sundaram, Priyadarshini Jaishankar, Philip W Payne, Pascal Druzgala
  • COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT
    Publication number: 20140378516
    Abstract: Embodiments of the present disclosure, in one aspect, relate to a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Application
    Filed: January 4, 2013
    Publication date: December 25, 2014
    Inventors: Yu Chen, Derek Nichols, Adam R. Renslo, Priyadarshini Jaishankar, Erica M.W. Lauterwasser
  • D2 ANTAGONISTS, METHODS OF SYNTHESIS AND METHODS OF USE
    Publication number: 20140350005
    Abstract: Provided are D2 or D3 antagonist compounds and pharmaceutical compositions of formula I and pharmaceutically acceptable salts thereof, or isomers thereof, wherein R1, R2 and R3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D2 or D3 receptor from the compounds of the invention.
    Type: Application
    Filed: February 19, 2014
    Publication date: November 27, 2014
    Inventors: GARY W. LUEHR, ARATHI SUNDARAM, PRIYADARSHINI JAISHANKAR, PHILIP W. PAYNE, PASCAL DRUZGALA
  • Dantagonists, methods of synthesis and methods of use
    Patent number: 8691836
    Abstract: Provided are D2 or D3 antagonist compounds and pharmaceutical compositions of formula I and pharmaceutically acceptable salts thereof, or isomers thereof, wherein R1, R2 and R3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D2 or D3 receptor from the compounds of the invention.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: April 8, 2014
    Assignee: Altos Therapeutics, LLC
    Inventors: Gary W. Luehr, Arathi Sundaram, Priyadarshini Jaishankar, Philip W. Payne, Pascal Druzgala
  • D2 ANTAGONISTS, METHODS OF SYNTHESIS AND METHODS OF USE
    Publication number: 20120010228
    Abstract: Provided are D2 or D3 antagonist compounds and pharmaceutical compositions of formula I and pharmaceutically acceptable salts thereof, or isomers thereof, wherein R1, R2 and R3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D2 or D3 receptor from the compounds of the invention.
    Type: Application
    Filed: June 17, 2011
    Publication date: January 12, 2012
    Inventors: Gary W. Luehr, Arathi Sundaram, Priyadarshini Jaishankar, Philip W. Payne, Pascal Druzgala