Abstract: The present invention discloses a composition and method for treating viral infections. The composition and method deliver inhibitors for preventing the entry of SARS-Cov-2 viral infections and the emerging variants are disclosed. The composition comprises a protease inhibitor comprising calcium salt of Tranexamic acid (Ca-TA). The protease inhibitor further comprises lithium salt of Tranexamic acid (Li-TA). The composition demonstrates efficacy in fibrin clot systems, where the Ca salt shows unexpected behavior of clot swelling, unlike TA. This inhibitor blocks the peptide or enzyme known as plasmin from interacting with fibrin (a protein) and subsequently breaking it down. TA is a safe and commonly used small molecule drug. The Ca-TA inhibitor interferes with the binding of the viral spike protein of SARS-CoV-2 to the human cell surface receptor angiotensin-converting enzyme-2 (ACE-2) to avoid infections caused by SARS-CoV-2 infections and emerging variants.