Abstract: A photopolymer plate manufacturing process utilizes a modified substrate and mask to generate pre-cut and interchangeable single and multi-part stamp dies. Using a modified substrate and mask, a conventional photopolymer plate can be manufactured with a plurality of independent pattern or stamp areas that are readily removable and replaceable on the substrate and do not require cutting. The resulting material is also securable to a plastic stamp or the like without an adhesive, thereby facilitating a stamp with exchangeable patterns. Additionally, with a further modified mask, the stamp dies can be manufactured in two or more separable pieces, which can then be selectively interchanged among multiple stamp dies.