Patents by Inventor Pu-Ping Lu

Pu-Ping Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Certain chemical entities, compositions, and methods
    Patent number: 7919511
    Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, and chemical entities, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: April 5, 2011
    Assignee: Cytokinetics, Inc.
    Inventors: Pu-Ping Lu, Xiangping Qian, Jeffrey T. Finer, Chihyuan (Grace) Chuang, Bradley P. Morgan, David J. Morgans, Jr.
  • Compounds, compositions and methods
    Patent number: 7910743
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: May 20, 2009
    Date of Patent: March 22, 2011
    Assignee: Cytokinetics, Inc.
    Inventors: Bradley P. Morgan, Alex Muci, Erica Kraynack, Pu-Ping Lu, Todd Tochimoto, David J. Morgans, Jr.
  • Certain chemical entities, compositions, and methods
    Patent number: 7851484
    Abstract: Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of muscle weakness and/or cachexia, as part of a rehabilitation or conditioning exercise regimen, or in the treatment of fraility, post-polio syndrome, obesity, sarcopenia, wasting syndrome, muscle spasm, and other indications.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: December 14, 2010
    Assignee: Cytokinetics, Inc.
    Inventors: Bradley P. Morgan, David J. Morgans, Jr., Gustave Bergnes, Alex Muci, Scott Collibee, Pu-Ping Lu, Luke W. Ashcraft, William F. Browne, IV, Marc Andrew Garard
  • Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas
    Patent number: 7825120
    Abstract: Certain substituted ((piperazin-1-ylmethyl)benzyl)urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and may be useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: December 13, 2006
    Date of Patent: November 2, 2010
    Assignee: Cytokinetics, Inc.
    Inventors: Bradley P. Morgan, Alex Muci, Erica A. Kraynack, Todd Tochimoto, Pu-Ping Lu, David J. Morgans, Jr.
  • Certain Chemical Entities, Compositions and Methods
    Publication number: 20100210645
    Abstract: Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of obesity, sarcopenia, wasting syndrome, frailty, cachexia, muscle spasm, post-surgical and post-traumatic muscle weakness, neuromuscular disease, and other indications.
    Type: Application
    Filed: April 22, 2010
    Publication date: August 19, 2010
    Inventors: Alex Muci, Jeffrey T. Finer, Pu-Ping Lu, Alan James Russell, Bradley P. Morgan, David J. Morgans, JR.
  • Certain Chemical Entities, Compositions and Methods
    Publication number: 20100210634
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: May 3, 2010
    Publication date: August 19, 2010
    Inventors: Bradley P. Morgan, Erica A. Kraynack, Pu-Ping Lu, Alex Muci, David J. Morgans, JR.
  • Certain indanyl urea modulators of the cardiac sarcomere
    Patent number: 7718657
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: December 13, 2006
    Date of Patent: May 18, 2010
    Assignee: Cytokinetics, Inc.
    Inventors: Bradley P. Morgan, Erica A. Kraynack, Pu-Ping Lu, Alex Muci, David J. Morgans, Jr.
  • CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
    Publication number: 20100093741
    Abstract: Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of obesity, sarcopenia, wasting syndrome, frailty, cachexia, muscle spasm, post-surgical and post-traumatic muscle weakness, neuromuscular disease, and other indications.
    Type: Application
    Filed: October 5, 2009
    Publication date: April 15, 2010
    Inventors: Alex Muci, Jeffrey T. Finer, Pu-Ping Lu, Alan James Russell, Bradley P. Morgan, David J. Morgans, JR.
  • Certain Chemical Entities, Compositions and Methods
    Publication number: 20100029680
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: June 11, 2009
    Publication date: February 4, 2010
    Inventors: Bradley P. Morgan, David J. Morgans, JR., Alex Muci, Pu-Ping Lu, Erica A. Kraynack, Todd Tochimoto
  • Compounds, Compositions and Methods
    Publication number: 20090324511
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: May 20, 2009
    Publication date: December 31, 2009
    Inventors: Bradley P. Morgan, Alex Muci, Erica Kraynack, Pu-Ping Lu, Todd Tochimoto, David J. Morgans, JR.
  • Certain chemical entities, compositions, and methods
    Publication number: 20090275537
    Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
    Type: Application
    Filed: August 11, 2008
    Publication date: November 5, 2009
    Inventors: Xiangping Qian, Chihyuan (Grace) Chuang, Pu-Ping Lu, Bing Yao, Qing (Kevin) Lu, Hong Jiang, Wenyue Wang, Bradley P. Morgan, David J. Morgans, JR.
  • Compositions and methods for treating heart failure
    Patent number: 7605164
    Abstract: Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: February 14, 2006
    Date of Patent: October 20, 2009
    Assignee: Cytokinetics, Inc.
    Inventors: Fady Malik, Adam Lewis Tomasi, Bainian Feng, Erica Anne Kraynack, Kathleen A. Elias, Pu-Ping Lu, Whitney Walter Smith, Xiangping Qian, David J. Morgans, Jr.
  • Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols, compositions thereof, and methods for their use
    Patent number: 7598248
    Abstract: Provided is at least one chemical entity chosen from compounds of Formula I and compounds of Formula II: and pharmaceutically acceptable salts thereof, compositions thereof, and methods for their use in modulating of one or more of skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, skeletal muscle, and skeletal sarcomere.
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: October 6, 2009
    Assignee: Cytokinetics, Inc.
    Inventors: Alex Muci, Jeffrey T. Finer, Pu-Ping Lu, Alan James Russell, Bradley P. Morgan, David J. Morgans, Jr.
  • Certain Chemical Entities, Compositions, and Methods
    Publication number: 20090198057
    Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
    Type: Application
    Filed: January 23, 2009
    Publication date: August 6, 2009
    Inventors: Pu-Ping LU, Chihyuan Grace CHUANG, Bradley P. MORGAN, David J. MORGANS, JR.
  • Compounds, Compositions and Methods
    Publication number: 20090192168
    Abstract: Certain substituted urea derivatives modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: December 19, 2008
    Publication date: July 30, 2009
    Inventors: Alex Muci, Pu-Ping Lu, Bradley P. Morgan, David J. Morgans, JR.
  • Compounds, Compositions and Methods
    Publication number: 20090176307
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: January 5, 2009
    Publication date: July 9, 2009
    Inventors: Bradley Paul Morgan, Kathleen A. Elias, Erica Anne Kraynack, Pu-Ping Lu, Fady Malik, Alex Muci, Xiangping Qian, Whitney Walter Smith, Todd Tochimoto, Adam Lewis Tomasi, David J. Morgans, JR.
  • Compounds, compositions and methods
    Patent number: 7538223
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: May 26, 2009
    Assignee: Cytokinetics, Inc.
    Inventors: Bradley P. Morgan, Alex Muci, Erica Kraynack, Pu-Ping Lu, Todd Tochimoto, David J. Morgans, Jr.
  • Compounds, Compositions and Methods
    Publication number: 20090099198
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: September 25, 2008
    Publication date: April 16, 2009
    Inventors: Bradley Paul Morgan, Alex Muci, Pu-Ping Lu, Erica Anne Kraynack, Todd Tochimoto, David J. Morgans, Jr.
  • Compounds, compositions and methods
    Patent number: 7507735
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: March 24, 2009
    Assignee: Cytokinetics, Inc.
    Inventors: Bradley Paul Morgan, Alex Muci, Pu-Ping Lu, Erica Anne Kraynack, Todd Tochimoto, David J. Morgans, Jr.
  • Compounds, compositions and methods
    Patent number: 7491826
    Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: February 17, 2009
    Assignee: Cytokinetics, Inc.
    Inventors: Bradley Paul Morgan, Kathleen A. Elias, Erica Anne Kraynack, Pu-Ping Lu, Fady Malik, Alex Muci, Xiangping Qian, Whitney Walter Smith, Todd Tochimoto, Adam Lewis Tomasi, David J. Morgans, Jr.