Patents by Inventor Pucha Yan

Pucha Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Asymmetrical hydrogenation reaction of ketonic acid compound
    Patent number: 10112884
    Abstract: The present invention relates to the technical field of organic chemistry, specifically an asymmetrical hydrogenation of an ?-ketonic acid compound, the technical proposal being as shown by the following formula: Wherein R1 is a phenyl, a substituted phenyl, a naphthyl a substituted naphthyl, a C1-C6 alkyl or aralkyl, the substitute is a C1-C6 alkyl, a C1-C6 alkoxy, a halogen, the number of the substituents is 1-3.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: October 30, 2018
    Inventors: Pucha Yan, Yuanqiang Li, Daqing Che, Xiangdong Zhang, Kang Chen, Yongliang Yan
  • Asymmetrical hydrogenation reaction of ketonic acid compound
    Publication number: 20170260119
    Abstract: The present invention relates to the technical field of organic chemistry, specifically an asymmetrical hydrogenation of an ?-ketonic acid compound, the technical proposal being as shown by the following formula: Wherein R1 is a phenyl, a substituted phenyl, a naphthyl a substituted naphthyl, a C1-C6 alkyl or aralkyl, the substitute is a C1-C6 alkyl, a C1-C6 alkoxy, a halogen, the number of the substituents is 1-3.
    Type: Application
    Filed: April 28, 2015
    Publication date: September 14, 2017
    Inventors: Pucha YAN, Yuanqiang LI, Daqing CHE, Xiangdong ZHANG, Kang CHEN, Yongliang YAN
  • Silodosin intermediate and preparation method therefor
    Patent number: 9394251
    Abstract: Disclosed are a silodosin intermediate and a preparation method thereof. The silodosin intermediate has the structure shown by the formula (A). X is hydrogen or bromide and R1 is hydrogen. The formyl group may be a group having the structure shown by the formula I. R7 is a protecting group of carboxyl, and R2 is 3-hydroxypropyl or a group having the structure shown by the formula II. W is a protecting group of hydroxyl. A compound of the formula (A) according to the present invention may further be used for preparing a compound having the structure shown by the formula (D). By means of the intermediate and the preparation method therefor provided by the present invention, high-purity optically pure silodosin can be obtained, and the optical purity is above 99%.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: July 19, 2016
    Assignee: Zhejiang Jiuzhou Pharmaceutical Co., Ltd.
    Inventors: Bin Zhang, Xiaowei Hu, Pucha Yan, Xianyi Zhang, Hongjun Gao, Yuanqiang Li, Daqing Che
  • Silodosin Intermediate and Preparation Method Therefor
    Publication number: 20150148548
    Abstract: Disclosed are a silodosin intermediate and a preparation method thereof. The silodosin intermediate has the structure shown by the formula (A). X is hydrogen or bromide and R1 is hydrogen. The formyl group may be a group having the structure shown by the formula I. R7 is a protecting group of carboxyl, and R2 is 3-hydroxypropyl or a group having the structure shown by the formula II. W is a protecting group of hydroxyl. A compound of the formula (A) according to the present invention may further be used for preparing a compound having the structure shown by the formula (D). By means of the intermediate and the preparation method therefor provided by the present invention, high-purity optically pure silodosin can be obtained, and the optical purity is above 99%.
    Type: Application
    Filed: July 27, 2012
    Publication date: May 28, 2015
    Inventors: Bin Zhang, Xiaowei Hu, Pucha Yan, Xianyi Zhang, Hongjun Gao, Yuanqiang Li, Daqing Che