Abstract: Provided are cell niche engineering platform which represents a valuable in vitro tool for investigating physiological and pathological cellular activities, an all-in-one technology to engineer cell niche (particularly soluble cell niche factors) with retained bioactivities, a mask-free, non-contact, biocompatible and multiphoton-based microfabrication and micropatterning method for engineering a spatially and quantitatively controllable soluble proteins/bioactive factors and cell-cell adhesion molecules. An universal cell niche engineering platform is provided that contributes to reconstituting heterogeneous native soluble cell niche for signal transduction modeling and drug screening studies.

Abstract: An embodiment of the invention provides a mechanism for controlling at least one ink transmission module, which controls a supply of ink using received control rotation. The mechanism includes an input, to receive control rotation. The mechanism also includes an output, to selectively transfer the control rotation to the ink transmission module. A control system is also provided to control the selective transfer of the output. The mechanism is moveable into a disengaged configuration by the control system, in which the output does not transfer rotation of the input to the ink transmission module, by a first predetermined sequence of rotations of the input, and into an engaged configuration, in which the output transfers rotation of the input to the ink transmission module, by a second predetermined sequence of rotations of the input.

Abstract: A sheet separator comprises an advancing roller driven to rotate to move a sheet forwards along a sheet path, and a reversing roller driven to rotate to move a sheet backwards along the path. The reversing roller and advancing roller are mounted adjacently and are relatively moveable between a pinched position and a separated position. The reversing roller has a torque limiter for allowing the reversing roller to slip and counter-rotate with the advancing roller when friction applied by the advancing roller on the pinched reversing roller exceeds a preset value. Overriding means mounted therein allows a sheet to pass over a roller when the rollers are separated and to remain idle when the rollers are pinched.

Abstract: A kicker system comprises a rotatable roller for advancing media along a media path toward a print zone. A kicker is mounted on the roller for pivotal movement transverse to the rotational axis of the roller. A cam surface configured to engage the kicker during a portion of a rotation of the roller to thereby pivotably retract the kicker out of the media path. The kicker can be selectively actuated by controlling the relative rotation of the roller and the cam surface.