Patents by Inventor Puja Sapra

Puja Sapra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SITE SPECIFIC HER2 ANTIBODY DRUG CONJUGATES
    Publication number: 20200377615
    Abstract: The present invention provides site specific HER2 antibody drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: June 3, 2020
    Publication date: December 3, 2020
    Applicant: Pfizer Inc.
    Inventors: Dangshe MA, Frank LOGANZO, Jr., Kimberly Ann MARQUETTE, Edmund Idris GRAZIANI, Puja SAPRA, Pavel STROP
  • Site specific HER2 antibody drug conjugates
    Patent number: 10689458
    Abstract: The present invention provides site specific HER2 antibody drug conjugates and methods for preparing and using the same.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: June 23, 2020
    Assignee: Pfizer Inc.
    Inventors: Dangshe Ma, Frank Loganzo, Jr., Kimberly Ann Marquette, Edmund Idris Graziani, Puja Sapra, Pavel Strop
  • Synergistic auristatin combinations
    Patent number: 10617670
    Abstract: This invention relates to combinations of an auristatin or an auristatin-based antibody-drug-conjugate (ADC) with second active agents including PI3K/mTOR inhibitors, MEK inhibitors, taxanes, or other anti-cancer agents, and methods of treating abnormal cell growth by administering these combinations to patients.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: April 14, 2020
    Assignee: Pfizer Inc.
    Inventors: Puja Sapra, Boris Shor
  • ANTIBODIES AND ANTIBODY FRAGMENTS FOR SITE-SPECIFIC CONJUGATION
    Publication number: 20200069764
    Abstract: The invention relates to polypeptides, antibodies, and antigen-binding fragments thereof, that comprise a substituted cysteine for site-specific conjugation.
    Type: Application
    Filed: November 19, 2019
    Publication date: March 5, 2020
    Applicant: Pfizer Inc.
    Inventors: Dangshe MA, Kimberly Ann MARQUETTE, Edmund Idris GRAZIANI, Puja SAPRA, Lawrence Nathan TUMEY, Nadira Anarkali PRASHAD, Kiran Manohar KHANDKE, Eric M. BENNETT, Lioudmila TCHISTIAKOVA
  • ANTI-EFNA4 ANTIBODY-DRUG CONJUGATES
    Publication number: 20180296691
    Abstract: The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: January 22, 2018
    Publication date: October 18, 2018
    Applicants: PFIZER, INC., ABBVIE STEMCENTRX LLC
    Inventors: Marc Isaac DAMELIN, Kiran Manohar KHANDKE, Puja SAPRA, Alexander John BANKOVICH, Scott J. DYLLA
  • SYNERGISTIC AURISTATIN COMBINATIONS
    Publication number: 20180228769
    Abstract: This invention relates to combinations of an auristatin or an auristatin-based antibody-drug-conjugate (ADC) with second active agents including PI3K/mTOR inhibitors, MEK inhibitors, taxanes, or other anti-cancer agents, and methods of treating abnormal cell growth by administering these combinations to patients.
    Type: Application
    Filed: September 29, 2015
    Publication date: August 16, 2018
    Inventors: Puja Sapra, Boris Shor
  • ANTI-PTK7 ANTIBODY-DRUG CONJUGATES
    Publication number: 20180094075
    Abstract: The present invention provides anti-PTK7 antibody-drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: September 1, 2017
    Publication date: April 5, 2018
    Applicants: PFIZER INC., ABBVIE STEMCENTRX LLC
    Inventors: Marc Isaac DAMELIN, Puja SAPRA, Alexander John BANKOVICH, Scott J. DYLLA
  • Anti-EFNA4 antibody-drug conjugates
    Patent number: 9872922
    Abstract: The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: January 23, 2018
    Assignees: Pfizer Inc., AbbVie Stemcentrx LLC
    Inventors: Marc Isaac Damelin, Kiran Manohar Khandke, Puja Sapra, Alexander John Bankovich, Scott J. Dylla
  • Anti-IL-13 receptor alpha 2 antibodies and antibody-drug conjugates
    Patent number: 9828428
    Abstract: Disclosed herein are anti-IL-13-R?2 antibodies and antibody drug conjugates and methods for preparing and using the same.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: November 28, 2017
    Assignee: Pfizer Inc.
    Inventors: Dangshe Ma, Fang Jin, Lioudmila Gennadievna Tchistiakova, Puja Sapra
  • ANTIBODY-DRUG CONJUGATES
    Publication number: 20170319711
    Abstract: Disclosed are anti-5T4 antibody drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: May 23, 2016
    Publication date: November 9, 2017
    Applicant: WYETH LLC
    Inventors: Hans-Peter Gerber, John Francis DiJoseph, Kiran Manohar Khandke, Kimberly Ann Marquette, Puja Sapra, Lioudmila Gennadievna Tchistiakova
  • Anti-PTK7 antibody-drug conjugates
    Patent number: 9777070
    Abstract: The present invention provides anti-PTK7 antibody-drug conjugates and methods for preparing and using the same.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: October 3, 2017
    Assignees: PFIZER INC, ABBVIE STEMCENTRX LLC
    Inventors: Marc Isaac Damelin, Puja Sapra, Alexander John Bankovich, Scott J. Dylla
  • ANTIBODIES AND ANTIBODY FRAGMENTS FOR SITE-SPECIFIC CONJUGATION
    Publication number: 20170216452
    Abstract: The invention relates to polypeptides, antibodies, and antigen-binding fragments thereof, that comprise a substituted cysteine for site-specific conjugation.
    Type: Application
    Filed: November 21, 2016
    Publication date: August 3, 2017
    Inventors: Dangshe MA, Kimberly Ann MARQUETTE, Edmund Idris GRAZIANI, Puja SAPRA, Lawrence Nathan TUMEY, Nadira Anarkali PRASHAD, Kiran Manohar KHANDKE, Eric M. BENNETT, Lioudmila TCHISTIAKOVA
  • SITE SPECIFIC HER2 ANTIBODY DRUG CONJUGATES
    Publication number: 20170151341
    Abstract: The present invention provides site specific HER2 antibody drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: November 21, 2016
    Publication date: June 1, 2017
    Applicant: Pfizer Inc.
    Inventors: Dangshe MA, Frank LOGANZO, JR., Kimberly Ann MARQUETTE, Edmund Idris GRAZIANI, Puja SAPRA, Pavel STROP
  • ANTI-EFNA4 ANTIBODY-DRUG CONJUGATES
    Publication number: 20170072066
    Abstract: The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: June 8, 2016
    Publication date: March 16, 2017
    Applicants: PFIZER, INC., STEMCENTRX, INC.
    Inventors: Marc Isaac DAMELIN, Kiran Manohar KHANDKE, Puja SAPRA, Alexander John BANKOVICH, Scott J. DYLLA
  • ANTI-NOTCH3 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES
    Publication number: 20170014526
    Abstract: The present invention provides for anti-Notch3 antibodies, anti-Notch3 antibody-drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: July 27, 2016
    Publication date: January 19, 2017
    Applicant: Pfizer Inc.
    Inventors: Kenneth G. Geles, Yijie Gao, Puja Sapra, Lioudmila Gennadievna Tchistiakova, Bin-Bing Stephen Zhou
  • Anti-Notch3 antibodies and antibody-drug conjugates
    Patent number: 9433687
    Abstract: The present invention provides for anti-Notch3 antibodies, anti-Notch3 antibody-drug conjugates and methods for preparing and using the same.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: September 6, 2016
    Assignee: Pfizer Inc.
    Inventors: Kenneth G. Geles, Yijie Gao, Puja Sapra, Lioudmila Gennadievna Tchistiakova, Bin-Bing Stephen Zhou
  • Anti-EFNA4 antibody-drug conjugates
    Patent number: 9381205
    Abstract: The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: July 5, 2016
    Assignees: Pfizer, Inc., Stemcentrx, Inc.
    Inventors: Marc Isaac Damelin, Kiran Manohar Khandke, Puja Sapra, Alexander John Bankovich, Scott J. Dylla
  • ANTI-PTK7 ANTIBODY-DRUG CONJUGATES
    Publication number: 20150315293
    Abstract: The present invention provides anti-PTK7 antibody-drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: April 27, 2015
    Publication date: November 5, 2015
    Applicants: STEMCENTRX, INC., PFIZER INC.
    Inventors: Marc Isaac DAMELIN, Puja SAPRA, Alexander John BANKOVICH, Scott J. DYLLA
  • ANTI-IL-13 RECEPTOR ALPHA 2 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES
    Publication number: 20150266962
    Abstract: Disclosed herein are anti-IL-13-R?2 antibodies and antibody drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: October 30, 2013
    Publication date: September 24, 2015
    Applicant: Pfizer Inc.
    Inventors: Dangshe Ma, Fang Jin, Lioudmila Gennadievna Tchistiakova, Puja Sapra
  • ANTI-EFNA4 ANTIBODY-DRUG CONJUGATES
    Publication number: 20150125472
    Abstract: The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: October 28, 2014
    Publication date: May 7, 2015
    Applicants: STEM CENTRX, INC., PFIZER, INC.
    Inventors: Marc Isaac DAMELIN, Kiran Manohar KHANDKE, Puja SAPRA, Alexander John BANKOVICH, Scott J. DYLLA