Abstract: In hemodynamic determination in medical imaging, the classifier is trained from synthetic data rather than relying on training data from other patients. A computer model (in silico) may be perturbed in many different ways to generate many different examples. The flow is calculated for each resulting example. A bench model (in vitro) may similarly be altered in many different ways. The flow is measured for each resulting example. The machine-learnt classifier uses features from medical scan data for a particular patient to estimate the blood flow based on mapping of features to flow learned from the synthetic data. Perturbations or alterations may account for therapy so that the machine-trained classifier may estimate the results of therapeutically altering a patient-specific input feature. Uncertainty may be handled by training the classifier to predict a distribution of possibilities given uncertain input distribution.

Abstract: A medical knowledge base in a digital, clinical system is upgraded. A storage with a knowledge base, being a SNOMED knowledge base, is provided in a web ontology format. Procedural data, representing clinical procedures for evaluation of a patient's health state, is received. The received procedural data is mapped in a set of SNOMED expressions. The SNOMED expressions are converted into statements in the web ontology format. The SNOMED knowledge base is upgraded with the received procedural data by adding the statements in the SNOMED knowledge base for providing a processable file with an upgraded version of the SNOMED knowledge base.

Abstract: A device and corresponding method are provided determining a consumed computing capacity of a first networking device exceeds the threshold for total capacity for processing monitoring data for a monitoring metric. An optimization engine determines a second networking device with unused computing capacity sufficient for processing the monitoring data generated by the first networking device. The optimization engine automatically moves the monitoring data for the monitoring metric generated by the first networking device to the second networking device and causes the second networking device to process the monitoring data.

Abstract: A technique for determining a cardiac metric from rest and stress perfusion cardiac magnetic resonance (CMR) images is provided. A neural network system for determining at least one cardiac metric from CMR images comprises an input layer configured to receive at least one CMR image representative of a rest perfusion state and at least one CMR image representative of a stress perfusion state. The neural network system further comprises an output layer configured to output at least one cardiac metric based on the at least one CMR image representative of the rest perfusion state and the at least one CMR image representative of the stress perfusion state. The neural network system with interconnections between the input layer and the output layer is trained by a plurality of datasets.

Abstract: Systems and methods for determining corresponding locations of points of interest in a plurality of input medical images are provided. A plurality of input medical images comprising a first input medical image and one or more additional input medical images is received. The first input medical image identifies a location of a point of interest. A set of features is extracted from each of the plurality of input medical images. Features between each of the sets of features are related using a machine learning based relational network. A location of the point of interest in each of the one or more additional input medical images that corresponds to the location of the point of interest in the first input medical image is identified based on the related features. The location of the point of interest in each of the one or more additional input medical images is output.

Abstract: Systems and methods for determining a quantity of interest of a patient comprise receiving patient data of the patient at a first physiological state. A value of a quantity of interest of the patient at the first physiological state is determined based on the patient data. The quantity of interest represents a medical characteristic of the patient. Features are extracted from the patient data, wherein the features which are extracted are based on the quantity of interest to be determined for the patient at a second physiological state. The value of the quantity of interest of the patient at the first physiological state is mapped to a value of the quantity of interest of the patient at the second physiological state based on the extracted features.

Abstract: Systems and methods for automated assessment of a vessel are provided. One or more input medical images of a vessel of a patient are received. A plurality of vessel assessment tasks for assessing the vessel is performed using a machine learning based model trained using multi-task learning. The plurality of vessel assessment tasks comprises segmentation of reference walls of the vessel from the one or more input medical images and segmentation of lumen of the vessel from the one or more input medical images. Results of the plurality of vessel assessment tasks are output.

Abstract: Systems and methods can be configured to determine a plurality of computing resource configurations used to perform machine learning model training jobs. A computing resource configuration can comprise: a first tuple including numbers of worker nodes and parameter server nodes, and a second tuple including resource allocations for the worker nodes and parameter server nodes. At least one machine learning training job can be executed using a first computing resource configuration having a first set of values associated with the first tuple. During the executing the machine learning training job: resource usage of the worker nodes and parameter server nodes caused by a second set of values associated with the second tuple can be monitored, and whether to adjust the second set of values can be determined. Whether a stopping criterion is satisfied can be determined. One of the plurality of computing resource configurations can be selected.

Abstract: Systems and methods are provided for optimizing a serverless workflow. Given a directed acyclic graph (“DAG”) defining functional relationships and a gamma tuning factor to indicate a preference between cost and performance, a serverless workflow corresponding to the DAG may be optimized. The optimization is carried out in accordance with the gamma tuning factor, and is carried out in sub-segments of the DAG called stages. In addition, systems for allowing disparate types of storage media to be utilized by a serverless platform to store data are disclosed. The serverless platforms maintain visibility of the storage media types underlying persistent volumes, and may store data in partitions across disparate types of storage media. For instance, one item of data may be stored partially at a byte addressed storage media and partially at a block addressed storage media.

Abstract: Systems and methods are provided for improving autotuning procedures. For example, the system can implement a task launcher, a scheduler, and an agent to launch, schedule, and execute decomposed autotuning stages, respectively. The scheduling policy implemented by the scheduler may perform operations beyond a simple scheduling policy (e.g., a FIFO-based scheduling policy), which produces a high queuing delay. By leveraging autotuning specific domain knowledge, this may help reduce queuing delay and improve resource utilization that is otherwise found in traditional systems.

Abstract: For decision support based on perfusion in medical imaging, a machine-learned model, such as a model trained with deep learning, generates perfusion examination information from CT scans of the patient. Other information, such as patient-specific information, may be used with the CT scans to generate the perfusion examination information. Since a machine-learned model is used, the perfusion examination information may be estimated from a spatial and/or temporally sparse number of scan shots or amount of CT dose. The results of perfusion imaging may be provided with less than the current, standard, or typical radiation dose.

Abstract: Systems and methods are provided for improved TCP congestion control designed to address “mixed coarse-grained-fine-grained signal” scenarios. A TCP sender of the present technology achieves this improvement by leveraging two TCP congestion windows for a TCP connection: (1) a “fine-grained TCP signal-dependent congestion window” which is adjusted in response to “fine-grained” TCP congestion signals (as intelligently classified/defined by the present technology); and (2) a “coarse-grained TCP signal-dependent congestion window” which is adjusted in response to “coarse-grained” TCP congestion signals (as intelligently classified/defined by the present technology). With these two novel/unique congestion windows at disposal, the TCP sender can then dynamically (and intelligently) select an appropriate congestion window for dictating packet transmission for a TCP connection (e.g., the contemporaneously smaller congestion window).

Abstract: Techniques for processing multiple cardiac images are disclosed. The processing may take place either during or after an angiography exam of a coronary artery of interest. The multiple cardiac images are obtained either during or after the angiography exam. Each of the multiple cardiac images depicts a respective segment of the coronary artery of interest. A geometric structure of the coronary artery of interest is determined based on the multiple cardiac images. A lumped parameter model of the coronary artery of interest is determined based on the geometric structure, and respective values of at least one hemodynamic index at a position of the coronary artery of interest is determined based on the lumped parameter model of the coronary artery of interest.

Abstract: Data privacy is a major concern when accessing and processing sensitive medical data. Homomorphic Encryption (HE) is one technique that preserves privacy while allowing computations to be performed on encrypted data. An encoding method enables typical HE schemes to operate on real-valued numbers of arbitrary precision and size by representing the numbers as a series of polynomial terms.

Abstract: A method includes processing at least one input dataset (using a multi-level processing algorithm, one or more of the at least one input dataset comprising imaging data of an echocardiography of a cardiovascular system of a patient. The multi-level processing algorithm comprises a multi-task level and a consolidation-task level. An input of the consolidation-task level is coupled to an output of the multi-task level. The multi-task level is configured to determine multiple diagnostic metrics of the cardiovascular system based on the at least one input dataset. The consolidation-task level is configured to determine a fitness of the cardiovascular system of the patient.

Abstract: Systems and methods can be configured to determine a plurality of computing resource configurations used to perform machine learning model training jobs. A computing resource configuration can comprise: a first tuple including numbers of worker nodes and parameter server nodes, and a second tuple including resource allocations for the worker nodes and parameter server nodes. At least one machine learning training job can be executed using a first computing resource configuration having a first set of values associated with the first tuple. During the executing the machine learning training job: resource usage of the worker nodes and parameter server nodes caused by a second set of values associated with the second tuple can be monitored, and whether to adjust the second set of values can be determined. Whether a stopping criterion is satisfied can be determined. One of the plurality of computing resource configurations can be selected.

Abstract: A value indicative of an ejection fraction, EF, of a cardiac chamber of a heart is based on a temporal sequence of cardiac magnetic resonance, CMR, images of the cardiac chamber. A neural network system has an input layer configured to receive the temporal sequence of a stack of slices of the CMR images along an axis of the heart. The temporal sequence is one or multiple consecutive cardiac cycles of the heart. The neural network system has an output layer configured to output the value indicative of the EF based on the temporal sequence. The neural network system has interconnections between the input layer and the output layer and is trained with a plurality of datasets. Each of the datasets comprises an instance temporal sequence of the stack of slices of the CMR images along the axis over one or multiple consecutive cardiac cycles for the input layer and an associated instance value indicative of the EF for the output layer.

Abstract: CMR imaging is synthesized, and/or machine learning for a CMR imaging task uses synthetic sample generation. A machine-learned model generates synthetic samples. For example, the machine-learned model generates the synthetic samples in response to input of values for two or more parameters from the group of electrocardiogram (ECG), an indication of image style, a number of slices, a pathology, a measure of heart function, sample image, and/or an indication of slice position relative to anatomy. The indication of image style may be in the form of a latent representation, which may be used as the only input or one of multiple inputs. These inputs provide for better control over generation of synthetic samples, providing for greater variance and breadth of samples then used to machine train for a CMR task.

Abstract: Example implementations relate to consensus protocols in a stretched network. According to an example, a distributed system includes continuously monitoring network performance and/or network latency among a cluster of a plurality of nodes in a distributed computer system. Leadership priority for each node is set based at least in part on the monitored network performance or network latency. Each node has a vote weight based at least in part on the leadership priority of the node. Each node's vote is biased by the node's vote weight. The node having a number of biased votes higher than a maximum possible number of votes biased by respective vote weights received by any other node in the cluster is selected as a leader node.

Abstract: A scheduling platform for scheduling serverless application tasks in persistent memory (PMEM) is provided. A profiler receives application requests from processes of serverless applications. The profiler categorizes the processes as persistent or non-persistent based on the application requests. A read/write batcher creates batches of the persistent requests including the read requests and write requests and assigns the batches to persistent memory banks. A scheduler creates a schedule of the batches to the persistent memory banks in a manner enabling optimization of job completion time.