Abstract: According to various embodiments, a microfluidic device may be provided. The microfluidic device may include: a plurality of valves connected to respective channels; a plurality of chambers, including a mixing chamber, a sample collection chamber, and a waste collection chamber; a binding member configured to bind biomolecules; and wherein flow of a liquid between the plurality of chambers is controlled by selectively opening and closing each valve of the plurality of valves to selectively allow air to be released from the channels connected to the respective valve.