Abstract: A pharmaceutical liquid composition containing the Pirfenidone in a very high concentration of more or less 25% by weight can be obtained by dissolving the Pirfenidone in diethylene glycol monoethyl ether. Even when the liquid medicinal compositions are stored for a long period of time, the Pirfenidone will not be recrystallized with a good chemical and physical stability. Furthermore, the liquid compositions are little irritating to the wounds on the mucous membrane of the skin and suitable for the manufacture of pharmaceutical formulations to be administered either via the oral, percutaneous, nasal or vaginal routes or by means of spray, patch, inhalation, injection or intravenous drip.

Abstract: To prepare an analgesic, anti-inflammatory cream, ibuprofen-S is dissolved in the PEG-7-glycerylcocoate and propylene glycol by slightly warming the solution to about 40 degrees Centigrade. Fractionated coconut oil, di-isopropyladipate, stearic acid, cetyl alcohol, polyoxyl-40-stearate, sorbitan-monostearate and propylparaben are mixed and heated to 70 degrees Centigrade. Methylparaben Sod. is dissolved in demineralized water and heated to 70 degrees Centigrade. The above oil and water phase components are mixed together, cooled to about 50 degrees Centigrade and the ibuprofen-S solution is added to the emulsion. The emulsion is homogenized and cooled to room temperature to form the cream.

Abstract: The product consists of tablets which contain at least 600 mg of ibuprofen and a binder, or a mixture of binders, based on cellulose and cellulose derivatives in the form of microspheres which are coated with an acrylic resin of defined nature and are compressed together with a disintegrant; the tablets are preferably also coated with a lacquer layer. As a consequence of the high content of active compound and its delayed release in the body, the therapeutic treatment with ibuprofen can be reduced to a minimum number of intakes and dose units per day.

Abstract: Disclosed are aqueous, stable, relatively concentrated solutions of diclofenac, which contain a mixture of propylene glycol and polyethylene glycol in defined quantitative proportions. The solutions preferably contain a local anesthetic such as lidocaine and a reducing agent as stabilizer.