Patents by Inventor Qi An

Qi An has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210136827
    Abstract: The present disclosure provides a grant free uplink transmission method, the method is performed at a user equipment side, comprising: determining, according to configuration information for grant free uplink transmission received from a base station, a radio network temporary identifier GF-RNTI for grant free uplink transmission, and transmitting an uplink signal; and monitoring feedback from the base station in a downlink control channel by using the determined GF-RNTI. The present disclosure also provides a user equipment and a base station for grant free uplink transmission.
    Type: Application
    Filed: April 29, 2019
    Publication date: May 6, 2021
    Inventors: Qi XIONG, Bin YU, Chen QIAN
  • Publication number: 20210128895
    Abstract: Disclosed is a drug delivery device comprising a body for holding a first solution and a second solution which are independent with each other; a pipeline delivery system comprising one or more pipelines for independently delivering the first solution and the second solution, respectively; a press device for sucking the first solution and the second solution into the pipelines, and a nozzle for delivering the first solution and the second solution in the pipelines to an administration site such that the first solution covers the second solution at the administration site.
    Type: Application
    Filed: October 30, 2020
    Publication date: May 6, 2021
    Inventors: Weiqin TONG, Xiaohong QI
  • Publication number: 20210130386
    Abstract: Provided herein are bifunctional compounds with a moiety (e.g., lenalidomide, thalidomide) that is a binder of an E3 ubiquitin ligase (e.g., Cereblon) and another moiety that is a binder of a target protein DOT1L to induce degradation of DOT1L. Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases, such as cancers). Provided also are methods of inducing the degradation of DOT1L by administering a bifunctional compound or composition described herein, wherein one component of the bifunctional compound is a binder of an E3 ubiquitin ligase (e.g., lenalidomide, thalidomide) and another component of the compound is a binder of the target protein DOT1L in a subject.
    Type: Application
    Filed: June 27, 2019
    Publication date: May 6, 2021
    Applicant: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Jun Qi, Scott Armstrong, Paul M. Park
  • Publication number: 20210130710
    Abstract: A process for treatment of PFO from a steam cracking zone includes selectively hydrogenating PFO or a portion thereof for conversion of polyaromatics compounds contained in the PFO into aromatic compounds with one benzene ring to produce a selectively hydrogenated stream. The selectively hydrogenated stream is reacted in the absence of added hydrogen for selective ring opening and dealkylation to produce a dealkylated BTX+ stream. The dealkylated BTX+ stream is separated into BTX compounds. Optionally the PFO is separated into a first stream containing C9+ aromatics compounds with one benzene ring, and a second stream containing C10+ aromatic compounds, whereby the first stream containing C9+ aromatics compounds with one benzene ring is passed to the ring opening step, and the feed to the selective hydrogenation step comprises all or a portion of the second stream containing C10+ aromatic compounds.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Inventors: Qi Xu, Raed Abudawoud
  • Publication number: 20210130838
    Abstract: A non-naturally occurring heterologous CRISPR-Cas12a genomic editing system is described, including or encoding at least one Cas12a ortholog endonuclease selected from among Lb5Cas12a, CMaCas12a, BsCas12a, BoCas12a, M1Cas12a, Mb2Cas12a, MbCas12a TsCas12a, and MAD7 endonucleases. The ortholog endonucleases enable genomic editing of plants at low temperatures, e.g., below 25° C. The CRISPR-Cas12a system can be employed for targeting PAM sites such as TTN, TTV, TTTV, NTTV, TATV, TATG, TATA, YTTN, GTTA, and GTTC, utilizing corresponding gRNAs, and is readily adapted to multiplexed editing operations of plants such as rice and other food crops.
    Type: Application
    Filed: November 5, 2020
    Publication date: May 6, 2021
    Inventors: Yiping QI, Yingxiao ZHANG
  • Publication number: 20210130714
    Abstract: A process for treatment of PFO from a steam cracking zone includes hydrodealkylating PFO or a portion thereof for conversion of polyaromatics compounds contained in the PFO into hydrodealkylated aromatic compounds with one benzene ring, a hydrodealkylated BTX+ stream. The hydrodealkylated BTX+ stream is separated into BTX compounds.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Inventors: Raed Abudawoud, Qi Xu
  • Publication number: 20210130708
    Abstract: A process for treatment of PFO from a steam cracking zone includes selectively hydrogenating PFO or a portion thereof for conversion of polyaromatics compounds contained in the PFO into aromatic compounds with one benzene ring to produce a selectively hydrogenated stream. The selectively hydrogenated stream is reacted in a fluid catalytic cracking reactor for selective ring opening and dealkylation to produce fluid catalytic cracking including light cycle oil. The light cycle oil is separated into BTX compounds. Optionally the PFO is separated into a first stream containing C9+ aromatics compounds with one benzene ring, and a second stream containing C10+ aromatic compounds, whereby the first stream containing C9+ aromatics compounds with one benzene ring is passed to the fluid catalytic cracking reactor, and the feed to the selective hydrogenation step comprises all or a portion of the second stream containing C10+ aromatic compounds.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Inventors: Qi Xu, Raed Abudawoud
  • Publication number: 20210130712
    Abstract: A process for treatment of PFO from a steam cracking zone includes hydrodealkylating PFO or a portion thereof for conversion of polyaromatics compounds contained in the PFO into hydrodealkylated aromatic compounds with one benzene ring, a hydrodealkylated BTX+ stream. In addition, a naphtha reformer is integrated, so that the hydrodealkylated BTX+ stream and a reformate stream are separated into BTX compounds.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Inventors: Raed Abudawoud, Qi Xu
  • Publication number: 20210136804
    Abstract: The present disclosure relates to a communication method and system for converging a 5th-Generation (5G) communication system for supporting higher data rates beyond a 4th-Generation (4G) system with a technology for Internet of Things (IoT). The present disclosure may be applied to intelligent services based on the 5G communication technology and the IoT-related technology, such as smart home, smart building, smart city, smart car, connected car, health care, digital education, smart retail, security and safety services. The present application discloses a method and device for transmitting a signal. the method comprises: detecting a downlink control channel by a user equipment (UE) using a compact downlink control information (DCI) format; acquiring configuration information by the UE in a preconfigured manner when the UE correctly detected the downlink control channel using the compact DCI format; performing an uplink transmission by the UE based on the configuration information.
    Type: Application
    Filed: April 2, 2019
    Publication date: May 6, 2021
    Inventors: Chen QIAN, Bin YU, Qi XIONG
  • Publication number: 20210130713
    Abstract: A process for treatment of PFO from a steam cracking zone includes selectively hydrogenating PFO or a portion thereof for conversion of polyaromatics compounds contained in the PFO into aromatic compounds with one benzene ring to produce a selectively hydrogenated stream. The selectively hydrogenated stream is reacted in a fluid catalytic cracking reactor for selective ring opening and dealkylation to produce fluid catalytic cracking including light cycle oil. In addition, a naphtha reformer is integrated, so that light cycle oil and a reformate stream are separated into BTX compounds. Optionally the PFO is separated into a first stream containing C9+ aromatics compounds with one benzene ring, and a second stream containing C10+ aromatic compounds, whereby the first stream containing C9+ aromatics compounds with one benzene ring is passed to the fluid catalytic cracking reactor, and the feed to the selective hydrogenation step comprises all or a portion of the second stream containing C10+ aromatic compounds.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Inventors: Qi Xu, Raed Abudawoud
  • Publication number: 20210130797
    Abstract: The disclosure relates to a sucrose phosphorylase mutant with improved enzyme activity, and construction method thereof and use thereof, and belongs to the technical field of genetic engineering. The amino acid sequence of the mutant of the disclosure is as shown in SEQ ID NO: 1. The mutant of the disclosure is based on sucrose phosphorylase derived from Leuconostoc mesenteroides, and subjected to site-directed mutagenesis to improve the enzyme activity of sucrose phosphorylase. The mutant is expressed in Corynebacterium glutamicum and used as a whole cell catalyst to produce 2-O-?-D-glycerol glucoside. At a 5L fermentation tank level, a large quantity of 2-O-?-D-glycerol glucoside can be produced efficiently in a short time, which is conducive to expanding the prospect of industrial application of sucrose phosphorylase for the production of 2-O-?-D-glycerol glucoside and realizing its large-scale industrial application.
    Type: Application
    Filed: June 8, 2020
    Publication date: May 6, 2021
    Inventors: Zhiming Rao, Peifeng Duan, Jianing Zhang, Xian Zhang, Taowei Yang, Meijuan Xu, Minglong Shao, Yu Liu, Ziwei Wang, Yan Chen, Qi Chen
  • Publication number: 20210130715
    Abstract: A process for treatment of PFO from a steam cracking zone includes selectively hydrogenating PFO or a portion thereof for conversion of polyaromatics compounds contained in the PFO into aromatic compounds with one benzene ring to produce a selectively hydrogenated stream. The selectively hydrogenated stream is selectively hydrocracked for selective ring opening and dealkylation to produce a selectively hydrocracked BTX+ stream. The selectively hydrocracked BTX+ stream is separated into BTX compounds. Optionally the PFO is separated into a first stream containing C9+ aromatics compounds with one benzene ring, and a second stream containing C10+ aromatic compounds, whereby the first stream containing C9+ aromatics compounds with one benzene ring is passed to the selective hydrocracking step, and the feed to the selective hydrogenation step comprises all or a portion of the second stream containing C10+ aromatic compounds.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Inventors: Qi Xu, Raed Abudawoud
  • Publication number: 20210132058
    Abstract: A time-resolved fluorescence immunochromatography kit for the simultaneous detection of a mixed pollutant of aflatoxin and carbaryl, a preparation method therefor, and an application thereof. The kit comprises a time-resolved fluorescence immunochromatography test strip and a sample reaction vial containing a europium-labeled anti-aflatoxin monoclonal antibody and a europium-labeled anti-carbaryl monoclonal antibody lyophilized product, detection lines of the time-resolved fluorescence immunochromatography test strip being coated with an aflatoxin-bovine serum albumin conjugate and a carbaryl-ovalbumin conjugate respectively, and the anti-carbaryl monoclonal antibody is produced by secretion of a hybridoma cell line Jnw1D2 with a preservation number of CCTCC NO. 0201654. The kit can be used for the simultaneous detection of aflatoxin and carbaryl content in a sample, and features simple and quick operations and a high sensitivity.
    Type: Application
    Filed: December 28, 2017
    Publication date: May 6, 2021
    Inventors: Peiwu LI, Xiaoqian TANG, Qi ZHANG, Zhaowei ZHANG
  • Publication number: 20210135403
    Abstract: An electrical connector electrically connects a first electrical module and a second electrical module, for insertion by the first electrical module along a first direction. The electrical connector includes a first group of terminals arranged in a row along a second direction, having multiple signal terminals and multiple ground terminals and forming at least one first terminal unit and at least one second terminal unit. Each of the terminals has a contact portion, a tail portion, and a middle portion located between the contact portion and the tail portion. In the second direction, the middle portions of the first terminal unit form a first row of the middle portions, and the middle portions of the second terminal unit form a second row of the middle portions. Viewing from the second direction, the first and second rows of the middle portions are staggered, thus improving the crosstalk.
    Type: Application
    Filed: August 27, 2020
    Publication date: May 6, 2021
    Inventors: Qi Xiao Yang, Yong Fu Wang
  • Publication number: 20210135194
    Abstract: The present disclosure provides a method of forming an electrode material for use in an electrochemical cell that cycles lithium ions. The method includes contacting a catalyst precursor with one or more electroactive materials to form a mixture. The catalyst precursor includes one or more metal salts. The method may also include activating the catalyst precursor in the mixture to form an activated mixture including an activated catalyst; and/or contacting one or more carbonaceous materials with the activated mixture to form the electrode material. The electrode material includes one or more electroactive particles that may be carbon coated disposed within a carbonaceous structure.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Lei WANG, Gongshin QI, Wei LI
  • Publication number: 20210130324
    Abstract: Provided herein are bifunctional compounds with a moiety (e.g., lenalidomide, thalidomide) that is a binder of an E3 ubiquitin ligase (e.g., Cereblon) and another moiety (e.g., RA190) that is a binder of the ubiquitin receptor RPN13 to induce degradation of RPN13 and thereby inhibit proteasome function. Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases, cancers, benign neoplasms, pathological angiogenesis, inflammatory diseases, and autoimmune diseases). Provided also are methods of inducing the degradation of ubiquitin receptor RPN13 by administering a bifunctional compound or composition described herein, wherein one component of the bifunctional compound is a binder of an E3 ubiquitin ligase (e.g., lenalidomide, thalidomide) and another component of the compound is a binder of ubiquitin receptor RPN13 (e.g., RA190) in a subject.
    Type: Application
    Filed: February 22, 2019
    Publication date: May 6, 2021
    Applicant: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Jun Qi, Kenneth C. Anderson, Lei Wu, Yan Song, Dharminder Chauhan
  • Publication number: 20210132842
    Abstract: A method, computer program product, and computer system for identifying, by a computing device, a current persisted value of a reclamation pool. A default value of the reclamation pool may be identified. The current persisted value may be compared with the default value to determine which is a higher value. The current persisted value may be selected as a minimum memory operating state of the reclamation pool when the current persisted value is higher than the default value. The default value may be selected as the minimum memory operating state of the reclamation pool when the default value is higher than the current persisted value plus a multiplier defining a threshold size.
    Type: Application
    Filed: November 6, 2019
    Publication date: May 6, 2021
    Inventors: Michael L. Burriss, Bolt Liangliang Liu, Eric Qi Yao, Doris Jia Qian
  • Publication number: 20210130716
    Abstract: A process for treatment of PFO from a steam cracking zone includes selectively hydrogenating PFO or a portion thereof for conversion of polyaromatics compounds contained in the PFO into aromatic compounds with one benzene ring to produce a selectively hydrogenated stream. The selectively hydrogenated stream is reacted in the absence of added hydrogen for selective ring opening and dealkylation to produce a dealkylated BTX+ stream. In addition, a naphtha reformer is integrated, so that the dealkylated BTX+ stream and a reformate stream are separated into BTX compounds. Optionally the PFO is separated into a first stream containing C9+ aromatics compounds with one benzene ring, and a second stream containing C10+ aromatic compounds, whereby the first stream containing C9+ aromatics compounds with one benzene ring is passed to the ring opening step, and the feed to the selective hydrogenation step comprises all or a portion of the second stream containing C10+ aromatic compounds.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Inventors: Qi Xu, Raed Abudawoud
  • Publication number: 20210134286
    Abstract: A system and method for selecting a target device out of a larger group of candidate devices for rendering a response from a virtual assistant to an end-user is disclosed. The system determines that a same trigger phrase included in an utterance has been received by multiple devices that are in proximity to one another at around the same time. These candidate devices can collect attention data, such as user gaze toward a device, to select the device that was most likely the intended recipient of the utterance. The system is configured to control the virtual assistant to render a response solely via the selected device.
    Type: Application
    Filed: December 20, 2019
    Publication date: May 6, 2021
    Applicant: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Nicholas David Burton, Arash Ghanaie-Sichanie, Qi Liu, Senthil Kumar Velayutham, Jian WU
  • Publication number: 20210130717
    Abstract: A process for treatment of PFO from a steam cracking zone includes selectively hydrogenating PFO or a portion thereof for conversion of polyaromatics compounds contained in the PFO into aromatic compounds with one benzene ring to produce a selectively hydrogenated stream. The selectively hydrogenated stream is selectively hydrocracked for selective ring opening and dealkylation to produce a selectively hydrocracked BTX+ stream. In addition, a naphtha reformer is integrated, so that the selectively hydrocracked BTX+ stream and a reformate stream are separated into BTX compounds. Optionally the PFO is separated into a first stream containing C9+ aromatics compounds with one benzene ring, and a second stream containing C10+ aromatic compounds, whereby the first stream containing C9+ aromatics compounds with one benzene ring is passed to the selective hydrocracking step, and the feed to the selective hydrogenation step comprises all or a portion of the second stream containing C10+ aromatic compounds.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 6, 2021
    Inventors: Qi Xu, Raed Abudawoud