Abstract: The present disclosure provides a method and a kit for detecting cell-free DNA (cfDNA) methylation, and belongs to the technical field of early cancer screening. The method includes the following steps: constructing and mixing a cfDNA library and a filter DNA to obtain a mixture of the cfDNA library and the filter DNA, co-immunoprecipitating the mixture with anti-5-methylcytosine (5mC) antibody, conducting methylation capture on methylated DNA fragments in the mixture, and purifying and eluting to obtain a captured product fragment; conducting amplification and enrichment, purification, recovery and screening to obtain a sequencing library; and sequencing on an Illumina sequencing platform, and bioinformatically analyzing acquired experimental data to know about the cfDNA methylation.

Abstract: A resin for grayscale digital light processing 3D printing includes a donor moiety, an acceptor moiety, a rigid moiety, a photoinitiator, and a photoabsorber. The donor moiety is an acrylate monomer with a side group of a free carbonyl, a primary amine on an acrylate, a secondary amine on an acrylate, and/or a tertiary amine on an acrylate. The acceptor moiety is different than the donor moiety and is an acrylate monomer with a side group of a free hydroxy, a primary amine, secondary amine, and/or an imine. And the rigid moiety is acrylate monomer with a side group of a cyclohexyl, a substituted cyclohexyl, or a bicyclic structure. A monolithic structure formed from the resin using grayscale digital light processing 3D printing can have a Young's modulus ranging from 0.1 MPa to 100 MPa.

Abstract: A step device includes: a mounting seat including a limiting part and configured to be mounted to a vehicle body; a step seat including an engaging part; a step mounted on the step seat; and an extension and retraction assembly connected to the mounting seat and the step seat, the extension and retraction assembly being configured to drive the step seat to move between an extended position where the engaging part is separated from the limiting part and a retracted position where the engaging part is engaged with the limiting part.

Abstract: The present disclosure includes apparatuses, methods, and systems for storing non-volatile memory initialization failures. In an example, a method can include initializing a volatile memory die, initializing a first non-volatile memory die in response to initializing the volatile memory die, copying executable instructions from the first non-volatile memory die to the volatile memory die in response to initializing the first non-volatile memory die, initializing the second non-volatile memory die in response to initializing the first non-volatile memory die, and storing a failure record in the first non-volatile memory die in response to an error occurring during the initialization of the second non-volatile memory die.

Abstract: This invention relates to a photocurable adhesive composition comprising at least one first hydroxyl terminated epoxidized unsaturated polyolefin having an epoxide equivalent weight less than 250 g/eq; at least one second hydroxyl terminated epoxidized unsaturated polyolefin having an epoxide equivalent weight greater than or equal to 250 g/eq; at least one dimer acid modified epoxy resin; at least one core-shell toughening agent; at least one polyol component; and at least one cationic photoinitiator. The cured product of the photocurable adhesive composition of the present invention shows excellent acid resistance and elongation property and is therefore suitable to be used for the protection of glass edge during the glass slimming process.

Abstract: The present disclosure relates to an acoustic output apparatus. The acoustic output apparatus may include an earphone core including at least one acoustic driver for outputting sound though one or more sound guiding holes set on the acoustic output apparatus, a controller configured to cause the at least one acoustic driver to output sound, a power source assembly configured to provide electrical power to the earphone core, the one or more sensors, and the controller, and an interactive control component configured to allow an interaction between a user and the acoustic output apparatus.

Abstract: A process and a device for continuous flow side-chain alkylation which relate to the technical field of organic synthesis. In this process and the device for continuous flow side-chain alkylation, an ibuprofen raw material is prepared with alkylbenzene as a raw material. This raw material alkylbenzene is easily available and has a low cost, and is suitable for scale-up production. Moreover, an entire preparation process adopts continuous chemical synthesis, and a reaction time of each stage can be precisely controlled, which is beneficial to control a total reaction time and reduce an amount of impurities produced. In this way, a purity and a yield of the ibuprofen raw material are improved. In summary, a continuous synthesis method for side-chain alkylation of alkylbenzene provided by the present disclosure shows a low cost and a high yield.

Abstract: The invention provides methods and compositions for selectively suppressing the expression of a recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides methods and compositions for inducing male sterility in a transgenic plant. Plants, plant cells, plant parts, seeds, and commodity products including such compositions are aspects of the invention.

Abstract: Present application discloses a method and a device in a node for wireless communications. A first node receives a first signaling, the first signaling triggering a first channel sensing; and performs the first channel sensing, the first channel sensing used for determining a first time-frequency resource block; and transmits a second signaling, the second signaling indicating a target identifier and the first time-frequency resource block; the first signaling indicates a first identifier and a first parameter; the first identifier indicates a second node; the first parameter comprises at least one of a first resource pool, a first priority, a first time length or a first frequency-domain resource size; the first parameter is used for performing the first channel sensing; the first identifier is used for determining the target identifier. The present application can reduce the scheduling delay and signaling interaction overhead caused by inter-user coordination.

Abstract: The present invention provides a Mycobacterium tuberculosis intein splicing inhibitor screening system, where Mycobacterium smegmatis is used as a model bacterium, a gene sequence of a protein regulated by an intein is inserted into a 65S site of a kanamycin-resistant protein gene, a vector with first antibiotic resistance is used for constructing a recombinant plasmid, and the recombinant plasmid is transferred into Mycobacterium smegmatis and is cultured in a medium containing a first antibiotic and kanamycin, to obtain the Mycobacterium tuberculosis intein splicing inhibitor screening system. The first antibiotic is any antibiotic other than kanamycin.

Abstract: A print recognition substrate and a print recognition apparatus. The print recognition substrate includes a base substrate, which includes a data line and a gate line crossing each other; a light shielding structure, located on the base substrate, and including a metal layer, and an orthographic projection of the light shielding structure on the base substrate does not overlap with orthographic projections of the data line and the gate line on the base substrate; a photoelectric conversion structure, located on the side of the light shielding structure away from the base substrate, and an orthographic projection of the photoelectric conversion structure on the base substrate is located in an orthographic projection of the light shielding structure on the base substrate, and a distance between an edge of the photoelectric conversion structure and an edge of the light shielding structure is less than or equal to 3 ?m.

Abstract: Described are modified release softgel capsules including a pH dependent shell composition that encapsulated a controlled release fill composition, methods of preparation thereof, and methods of use thereof. The pH dependent shell composition may be characterized in that the delayed release nature of the capsules may be achieved without a separate pH dependent coating or added conventional pH dependent polymers. The softgels provide a dual controlled release platform which facilitates delivery of the active agent to a target location in the gastrointestinal tract and a controlled release profile of the active agent at said target location in the gastrointestinal tract.

Abstract: A master batch composition for a weight-reduced plastic product includes a carrier resin, a core-shell foaming agent, and at least one lubricant. The core-shell foaming agent includes at least one outer polymeric shell and at least one inner foaming agent core. The outer polymeric shell encapsulates the inner foaming agent core. The inner foaming agent core includes alkane. The master batch composition is configured to be integrated into the weight-reduced plastic product by extrusion blow molding with a base plastic resin to create a foamed plastic having a foaming pore size from 10 to 80 ?m.

Abstract: Provided is a method for locating a terminal. The method includes: reading speed information; determining a plurality of initial locating positions in a region to be located, and respectively obtaining a trajectory corresponding to each initial locating position of the plurality of initial locating positions by calculating according to the speed information; acquiring a position of a base station, and obtaining theoretical channel state information of trajectory points in the trajectory corresponding to each initial locating position by calculating according to the position of the base station; acquiring actual channel state information of the trajectory points in the trajectory corresponding to each initial locating position; and determining a target locating position from the plurality of initial locating positions according to the theoretical channel state information and the actual channel state information.

Abstract: The present disclosure discloses a multi-task joint computing unloading and resource allocation method based on D2D (Device-to-Device) communication. For solving the problems that computing resources of a local terminal cannot complete all computing tasks on time when there are multiple computing tasks with delay requirements on a local terminal, the method introduces a computing unloading mechanism to reduce the delay and the overhead of the local terminal itself. The method is based on a D2D communication technology. In the scenario where mobile terminals are densely distributed, the local terminal can unload the computing tasks at the same time to several surrounding idle terminals for processing. According to the method, a total overhead objective function is established in consideration of the task delay, energy consumption, and unloading fee.

Abstract: In one aspect, a hybrid circuit protection device for current-limiting a fault current between a source and a load during a fault is provided. The hybrid circuit protection device includes an input configured to couple to the source, an output configured to couple to the load, a return configured to couple the source to the load, a main switch configured to selectively couple the input to the output, a switching network coupled in parallel with the main switch, and a controller. The controller is configured to determine that the main switch has opened in response to the fault current, where the fault current has an initial value, and activate the switching network to current-limit the fault current to less than the initial value during the fault.

Abstract: The present disclosure relates to a communication method and system for converging a 5th-Generation (5G) communication system for supporting higher data rates beyond a 4th-Generation (4G) system with a technology for Internet of Things (IoT). The present disclosure may be applied to intelligent services based on the 5G communication technology and the IoT-related technology, such as smart home, smart building, smart city, smart car, connected car, health care, digital education, smart retail, security and safety services.

Abstract: Various embodiments include a method for deploying field device into an Internet of Things (IoT). The method may include: acquiring information from a field device using an edge device; transmitting the acquired information to a cloud platform; wherein the information comprises data and an industrial IoT model; converting the industrial IoT model into a graph; performing similarity analysis based on the graph; classifying the industrial IoT model based on the similarity analysis; generating a first industrial IoT model comprising a type or an example; performing data mapping on the first industrial IoT model; and operating the field device as part of the IoT.

Abstract: A method of normalizing detector elements in an imaging system is described herein. The method includes a line source that is easier to handle for a user, and decouples the normalization of the detector elements into a transaxial domain and an axial domain in order to isolate errors due to positioning of the line source. Additional simulations are performed to augment the real scanner normalization. A simulation of a simulated line source closely matching the real line source can be performed to isolate errors due to physical properties of the crystals and position of the crystals in the system, wherein the simulated detector crystals are otherwise modeled uniformly. A simulation of a simulated cylinder source can be performed to determine errors due to other effects stemming from gaps between the detector crystals.

Abstract: Systems and methods for monitoring patients for risk of worsening heart failure (WHF) are discussed. A patient management system includes a sensor circuit to receive respiration measurements, and an input device to receive patient dyspnea descriptor indicating dyspnea symptom severity. The system includes a risk analyzer circuit to trend the respiration measurement over time, and to generate a WHF risk indicator using both the trended respiration measurement and the received dyspnea descriptor. A control circuit controls the receiver circuit to receive the dyspnea descriptor in response to the trended respiration measurement satisfying a specific condition. The system can present the WHF risk indicator to a user or a process, or deliver or adjust a HF therapy based on the WHF risk indicator.