Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: The disclosure provides a display backlight unit and its light down conversion film. The light down conversion film may include a quantum-dot layer sandwiched between input substrate and an exit substrate. First and second refractive asymmetric micro-prisms are disposed on two opposite input and first exit surfaces of the input substrate, respectively. On the input surface of the input substrate, multiple arrays of the asymmetric refractive asymmetric micro-prisms preserve the large off-axis angle of incident light with first wavelength. On the first exit surface of the input substrate, multiple arrays of the refractive asymmetric micro-prisms increase the reflectance of the large incident angle light. A second exit surface of the exit substrate includes refractive symmetric micro-prisms. The refractive asymmetric micro-prisms of the input substrate and the refractive asymmetric micro-prisms of the exit substrate have rounded tips and valleys for enhancing refraction of the first light and the second light.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Abstract: The present invention relates generally to compositions for topical application to the skin which comprise at least one DICKKOPF-1 expression modulator and the use of such compositions to provide benefits to the skin, including but not limited to lightening or darkening skin; treating hyper or hypopigmented skin; increasing or decreasing skin thickness; reducing or increasing skin hirsuteness; and/or changing skin phenotype from non-palmoplantar to palmoplantar.

Abstract: A planar light guide film for a backlight unit having at least one point light source is disclosed. The light guide film includes a light input surface for receiving light from the point light source, a light redirecting surface for redirecting light received from the light input surface and a light output surface for outputting at least the light redirected from the light redirecting surface. The light input surface further includes a composite lens structure having a first and second circular tip segment each circular tip segment with a first contact angle, and a first and second circular base segment each circular base segment with a top and bottom contact angle, the contact angles of the circular base segments being less than the contact angle of the circular tip segments.

Abstract: A planar light guide film for a backlight unit having at least one point light source is disclosed. The light guide film includes a light input surface for receiving light from the point light source, a light redirecting surface for redirecting light received from the light input surface and a light output surface for outputting at least the light redirected from the light redirecting surface. The light input surface includes a composite lens structure having a first and second circular tip segment each circular tip segment with a first contact angle, and a first and second circular base segment each circular base segment with a top and bottom contact angle, the contact angles of the circular base segments being greater than the contact angle of the circular tip segments.

Abstract: 8?,14-Dihydroxy-7,8-dihydrocodeinone is described.

Abstract: The present invention relates generally to compositions for topical application to the skin which comprise at least one DICKKOPF-1 expression modulator and the use of such compositions to provide benefits to the skin, including but not limited to lightening or darkening skin; treating hyper or hypopigmented skin; increasing or decreasing skin thickness; reducing or increasing skin hirsuteness; and/or changing skin phenotype from non-palmoplantar to palmoplantar.

Abstract: A cosmetic composition comprising a first emulsion and a second emulsion and optionally one or more additional emulsions, each of said two or more emulsions being discretely contained within the composition and comprising an inner phase and an outer phase, each of said two or more emulsions being independently a water-in-oil emulsion, an oil-in-water emulsion, an oil-in-oil emulsion, a polyol-in-oil emulsion, a water-in-silicone emulsion, a silicone-in-water emulsion, or a polyol-in-silicone emulsion in physical contact with at least one other emulsion, at least one of said two or more emulsions being visually distinct from the others, and each of said two or more emulsions as well as said composition being independently both physically and visually stable within the composition for at least six months at ambient temperature.