Abstract: Embodiments provide clock synchronization methods and control systems. In some embodiments a control system includes a first controller and a second controller. In some embodiments the first controller includes a first clock unit and a second clock unit, and the second controller includes a third clock unit. In some embodiments, a clock of the first clock unit may be different from a clock of the third clock unit, and a clock of the second clock unit may be the same as the clock of the third clock unit. In some embodiments, a method includes the first controller and the second controller add a timestamp to sensor data by using a first clock. In some embodiments the first clock is the clock of the first clock unit or the clock of the third clock unit.

Abstract: A computer-implemented method, a computer system, and a computer program product for trajectory similarity search is provided. The present invention may include, in response to receiving, by one or more processors, a search request for at least one trajectory similar to a query trajectory, determining, by one or more processors, a respective similarity between a query trajectory and a plurality of trajectories by calculating, in a synchronized way, a spatial distance measure and a time difference measure between the query trajectory and the plurality of trajectories. The present invention may further include, identifying, by one or more processors, the at least one trajectory from the plurality of trajectories based on the respective similarity between the query trajectory and the plurality of trajectories.

Abstract: The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.

Abstract: The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.

Abstract: Data format conversion processing of an accelerator accessed by a processor of a computing environment is reduced. The processor and accelerator use different data formats, and the accelerator is configured to perform an input conversion to convert data from a processor data format to an accelerator data format prior to performing an operation using the data, and an output conversion to convert resultant data from accelerator data format back to processor data format after performing the operation. The reducing includes determining that adjoining operations of a process to run on the processor and accelerator are to be performed by the accelerator, where the adjoining operations include a source operation and destination operation. Further, the reducing includes blocking an output data format conversion of the source operation and an input data format conversion of the input data for the destination operation.

Abstract: A vehicle control technical solution is provided. The solution relates to the field of computer technologies, and particularly to the field of artificial intelligence technologies, such as autonomous driving technologies, intelligent transportation technologies. A vehicle control method includes: acquiring a state quantity error between a desired state quantity at a current moment and a real state quantity at a previous moment of a vehicle; determining a control quantity of the vehicle at the current moment based on the state quantity error and a mapping relationship between the control quantity of the vehicle and the state quantity error; and controlling a driving behavior of the vehicle based on the control quantity at the current moment to obtain a real state quantity at the current moment.

Abstract: The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.

Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.

Abstract: Data format conversion processing of an accelerator accessed by a processor of a computing environment is reduced. The processor and accelerator use different data formats, and the accelerator is configured to perform an input conversion to convert data from a processor data format to an accelerator data format prior to performing an operation using the data, and an output conversion to convert resultant data from accelerator data format back to processor data format after performing the operation. The reducing includes determining that adjoining operations of a process to run on the processor and accelerator are to be performed by the accelerator, where the adjoining operations include a source operation and destination operation. Further, the reducing includes identifying for removal output data format conversion of output data of the source operation for input to the destination operation, and input data format conversion of the input to the destination operation.

Abstract: Disclosed are an optimization method and apparatus for an Interferometric Synthetic Aperture Radar (InSAR) time-series phase. The optimization method includes: obtaining a time-series SAR data set, and performing registration and L-looks processing on the time-series SAR data set to obtain an L-looks intensity data set and an interferometric data set respectively; taking the L-looks intensity data set as a reference, obtaining a preset digital elevation model (DEM) and a preset land cover image, performing registration and geocoding on the preset DEM to obtain a digital elevation in a SAR image coordinate system, and performing registration and geocoding on the preset land cover image to obtain a land cover image in the SAR image coordinate system; performing a differential operation on the interferometric data set to obtain a differential interferometric data set; and estimating a covariance matrix at each spatial pixel position, and estimating and obtaining an optimized time-series phase.

Abstract: The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.

Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.

Abstract: The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.

Abstract: A semiconductor structure and its fabrication method are provided in the present disclosure. The method includes providing a layer to-be-etched, including first regions and second regions. The method further includes forming a plurality of discrete first sacrificial layers on the layer to-be-etched, where a plurality of openings is between the plurality of first sacrificial layers and includes first openings on the first regions. The method further includes forming initial sidewall spacer structures on sidewalls of the plurality of first sacrificial layers, where the initial sidewall spacer structures include first sidewall spacers, and the first sidewall spacers fill the first openings. The method further includes, using the first sidewall spacers as an alignment mark, forming a first mask layer on the layer to-be-etched and the initial sidewall spacer structures, where the first mask layer exposes a portion of the layer to-be-etched and a portion of the initial sidewall spacer structures.

Abstract: The present invention relates inter alia to expression vector production as well as application to the production of host cells for protein repertoire expression and high-throughput screening. The invention also relates to primers useful for PCR amplification of nucleotide sequences encoding human antibody variable domains.

Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.

Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising the antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in the methods.

Abstract: The present invention relates inter alia to expression vector production as well as application to the production of host cells for protein repertoire expression and high-throughput screening. The invention also relates to primers useful for PCR amplification of nucleotide sequences encoding human antibody variable domains.

Abstract: The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising the antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in the methods.

Abstract: The invention relates to Proprotein Convertase Subtilisin Kexin type 9 (PCSK9) antagonists, such as antibodies and fragments, as well as methods, uses and combinations.