Patents by Inventor Qi Wen

Qi Wen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11957743
    Abstract: A Streptococcus suis (S. suis) vaccine is provided. For the S. suis vaccine, an antigen is a protein with an amino acid sequence shown in SEQ ID NO: 2. A preparation method of the S. suis vaccine is provided, including the following steps: mixing a white oil and aluminum stearate to obtain a white oil adjuvant; adding poly sorbate 80 to an aqueous solution of the protein with the amino acid sequence shown in SEQ ID NO: 2, and thoroughly mixing to obtain an antigen solution; and mixing the antigen solution with the white oil adjuvant according to a volume ratio of (0.5-1.5):2, and emulsifying to obtain the S. suis vaccine. An animal immunized with the S. suis vaccine of the present disclosure can effectively resist the attack of S. suis serotype 2, 3, and 31, with a vaccine protection rate as high as 100%.
    Type: Grant
    Filed: June 10, 2022
    Date of Patent: April 16, 2024
    Assignee: JIANGSU ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Qi Xiao, Xialing Zhao, Hongjie Fan, Xiaoguo Huang, Wenxian Qian, Libin Wen, Haodan Zhu, Yanxiu Ni, Junming Zhou, Dandan Wang, Jiaqiang Niu, Kongwang He
  • Patent number: 11961626
    Abstract: A fiber optic based particle manipulation system employs one or more optical fibers for emanating a refracted optical manipulation signal directed at a target particle for fixing or manipulating the particle for examination, research and manufacturing. A target particle may be a living cell or inanimate sample or compound of matter. An alignment linkage controls optical fibers carrying the manipulation signal for focusing one or more manipulation signals on the target particle. Manipulated particles occupy a fluid medium of either liquid or gas, and are responsive to the manipulation signal based on both photon bombardment and temperature differential from photon contact. The temperature differential is based on surface properties of the target particle, as smooth particles tend to exhibit a greater thermal differential for stronger displacement forces driving or affecting the target particle.
    Type: Grant
    Filed: January 26, 2022
    Date of Patent: April 16, 2024
    Assignee: Worcester Polytechnic Institute
    Inventors: Yuxiang Liu, Chaoyang Ti, Qi Wen
  • Publication number: 20240116387
    Abstract: A charging method includes: obtaining a first voltage of a charging port of a vehicle; determining a target buck value based on the first voltage, adjusting a voltage on a buck side of a buck-boost converter of the vehicle based on the target buck value, and sending the target buck value to a charging pile to enable the charging pile to determine an output voltage of the charging pile based on the target buck value; increasing a charging demand current of the vehicle to a maximum allowable charging current of the vehicle; and charging the vehicle according to the maximum allowable charging current.
    Type: Application
    Filed: December 14, 2023
    Publication date: April 11, 2024
    Inventors: Yubo LIAN, Heping LING, Junhua LIU, Fengjun AN, Qi WEN
  • Patent number: 11918635
    Abstract: A method and a platform for detecting an immunogenicity of a tumor neoantigen are provided. Specifically, the detection method includes the following steps: culturing human peripheral blood monocytes ex vivo for 13 days, adding an antigenic peptide fragment of human influenza virus and stimulating and activating cytokines, antigenic peptides, and immunoadjuvants during the 13 days, and finally conducting enzyme-linked immunospot (ELISPOT) chromogenic reaction and instrument-based scanning, counting, and analysis to detect the immunogenicity of tumor neoantigen. An application of the detection method and platform in biomedicine is provided. Compared with the prior art, the detection method and platform have advantages and characteristics of a short detection period, high convenience, low consumption of experimental cells, and low detection cost. Therefore, the detection method and platform can be used for ex vivo high-throughput assay for the immunogenicity of the tumor neoantigen.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: March 5, 2024
    Assignees: NeoCura Bio-Medical Technology Co., Ltd, Beijing Neocurna Biotechnology corporation, Shenzhen Neocurna Biotechnology corporation
    Inventors: Youdong Pan, Qi Song, Ji Wan, Jun-Yuan Huang, An Xiao, Gang Liu, Ying Wen
  • Publication number: 20240036927
    Abstract: A method for processing a workflow in combination with a task, a task processing method, and related devices are provided. During reporting the workflow, a task control is created in a preset area, in response to a task addition instruction. A target task to be added may be inserted into the task control for display. In this way, the workflow added with the target task can be reported to a target user.
    Type: Application
    Filed: July 21, 2023
    Publication date: February 1, 2024
    Inventors: Jiangfeng MA, Wei HUANG, Xinlei GUO, Qi WEN, Shengxin QIU
  • Publication number: 20230141928
    Abstract: Machine-learning (ML) techniques and models are described for predicting the number and severity of network attacks within a specified timeframe, such as the next fifteen minutes. In some embodiments, the techniques including training a ML model based on features extracted from a training dataset and applying the trained ML model to estimate (a) the probability of an attack happening on an account within a specified timeframe; (b) how many attacks are predicted to occur in the specified timeframe (if any); and/or (c) the severity of the attacks predicted to occur. A system may deploy preventative measures based on the ML model output to counter or mitigate the effects of predicted and coordinated network attacks.
    Type: Application
    Filed: October 13, 2021
    Publication date: May 11, 2023
    Applicant: Oracle International Corporation
    Inventors: Ján Sterba, Venkatakrishnan Gopalakrishnan, May Bich Nhi Lam, Yunjiao Xue, Nana Lei, Edward C. Cheng, Hayward Ivan Craig Welcher, Jacob Becker West, Qi Wen Cao
  • Publication number: 20230134546
    Abstract: Machine-learning techniques and models are described for alerting users to attacks on accounts in real-time or near real-time. In some embodiments, an attack detection model uses Natural Language Processing (NLP) and multi-level classification techniques to monitor login attempts and detect attacks. The model may use NLP to convert text associated with account activity to numerical vectors, where the vectors include scores and/or other numerical values computed based on the meaning of the converted text. The model may further include a set of classifiers trained to learn patterns in the numerical vectors that are predictive of a network attack. The model may assign labels to events based on the predicted likelihood that the event is an attack. The system may deploy real-time preventative or corrective measures based on the ML model output to counter or mitigate the effects of an attack.
    Type: Application
    Filed: October 29, 2021
    Publication date: May 4, 2023
    Applicant: Oracle International Corporation
    Inventors: Venkatakrishnan Gopalakrishnan, Ján Sterba, May Bich Nhi Lam, Yunjiao Xue, Nana Lei, Edward C. Cheng, Hayward Ivan Craig Welcher, Jacob Becker West, Qi Wen Cao
  • Patent number: 11568272
    Abstract: Aspects of the invention include a computer-implemented method that receives, by a processor, an ensemble decision tree and generates, by the processor, native code from the ensemble decision tree. The method compiles, by the processor, the native code into machine language and scores, by the processor, the execution time of the native code. The method dynamically reoptimizes, by the processor, portions of the native code corresponding to the most traversed portion of the ensemble decision tree.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: January 31, 2023
    Assignee: International Business Machines Corporation
    Inventors: Jean-François Puget, Ke Wei Wei, Xinke Wang, Qi Wen, Chu Yun Tong, Tian Tian, Chi Liu
  • Publication number: 20220238246
    Abstract: A fiber optic based particle manipulation system employs one or more optical fibers for emanating a refracted optical manipulation signal directed at a target particle for fixing or manipulating the particle for examination, research and manufacturing. A target particle may be a living cell or inanimate sample or compound of matter. An alignment linkage controls optical fibers carrying the manipulation signal for focusing one or more manipulation signals on the target particle. Manipulated particles occupy a fluid medium of either liquid or gas, and are responsive to the manipulation signal based on both photon bombardment and temperature differential from photon contact. The temperature differential is based on surface properties of the target particle, as smooth particles tend to exhibit a greater thermal differential for stronger displacement forces driving or affecting the target particle.
    Type: Application
    Filed: January 26, 2022
    Publication date: July 28, 2022
    Inventors: Yuxiang Liu, Chaoyang Ti, Qi Wen
  • Publication number: 20210383244
    Abstract: Aspects of the invention include a computer-implemented method that receives, by a processor, an ensemble decision tree and generates, by the processor, native code from the ensemble decision tree. The method compiles, by the processor, the native code into machine language and scores, by the processor, the execution time of the native code. The method dynamically reoptimizes, by the processor, portions of the native code corresponding to the most traversed portion of the ensemble decision tree.
    Type: Application
    Filed: June 9, 2020
    Publication date: December 9, 2021
    Inventors: Jean-François Puget, Ke Wei Wei, Xinke Wang, Qi Wen, Chu Yun Tong, Tian Tian, Chi Liu
  • Publication number: 20200123689
    Abstract: A method for preparing a capacitive stress sensing intelligent fabric. Conductive yarn serves as an electrode of a capacitive sensor, and the conductive yarn is obtained by means of direct preparation, coating, doping, etc.; an insulating elastomer is coated on the conductive yarn as a dielectric material; and the conductive yarn, which has been subjected to insulation processing, is interlaced among common yarns by using interweaving and overlapping structures among fabric yarns. A fabric sensing array is formed by means of a common manufacturing technique, and the method can be widely applied to force monitoring, etc., for intelligent garments, intelligent homes, touch-control screens, electronic skin and three-dimensional fabric composite materials.
    Type: Application
    Filed: January 22, 2018
    Publication date: April 23, 2020
    Inventors: Kun ZHANG, Qi WEN
  • Publication number: 20190378632
    Abstract: A plated product includes a component and an overall layer plated on a surface of the component. The overall layer includes a copper layer, a nickel layer, a nickel-tungsten layer, an inner golden layer, a palladium layer, an outer golden layer and a rhodium-ruthenium layer. The copper layer is plated on a surface of the component. The nickel layer, the nickel-tungsten layer, the inner golden layer, the palladium layer, the outer golden layer and the rhodium-ruthenium layer are plated on a surface of the copper layer in sequence.
    Type: Application
    Filed: May 13, 2019
    Publication date: December 12, 2019
    Inventors: CHIU-HSIEN YANG, QI-WEN XIAO, PENG LI
  • Patent number: 10467318
    Abstract: A method comprising receiving a request to create an import file for a document browser from a Personal Document Collection comprising a topic; retrieving a topic content associated with the topic from a content management system (CMS), wherein the topic content comprises a user defined content applied to a master topic content; generating a content page from the topic content, wherein the content page is configured to be displayed within the document browser; generating a navigation structure based on the topic content and the document browser; and compress the content page and the navigation structure into the import file.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: November 5, 2019
    Assignee: Futurewei Technologies, Inc.
    Inventors: Rhonda Truitt, Farhad Patel, Zhenzi Li, Qi Wen, Sally Martir
  • Publication number: 20170249323
    Abstract: A method comprising receiving a request to create an import file for a document browser from a Personal Document Collection comprising a topic; retrieving a topic content associated with the topic from a content management system (CMS), wherein the topic content comprises a user defined content applied to a master topic content; generating a content page from the topic content, wherein the content page is configured to be displayed within the document browser; generating a navigation structure based on the topic content and the document browser; and compress the content page and the navigation structure into the import file.
    Type: Application
    Filed: February 25, 2016
    Publication date: August 31, 2017
    Inventors: Rhonda Truitt, Farhad Patel, Zhenzi Li, Qi Wen, Sally Martir
  • Publication number: 20150252375
    Abstract: The present invention relates to transcriptional gene silencing (TGS) of endogenes in plants, plant tissue and plant cells. More specifically, the present invention relates to nucleic acid constructs that are capable of TGS of endogenes in plants, plant tissue and plant cells. The present invention further relates to methods of reducing endogenous gene expression in plants, plant tissues or plant cells by TGS using the nucleic acid constructs of the invention.
    Type: Application
    Filed: August 27, 2013
    Publication date: September 10, 2015
    Applicant: THE ROCKEFELLER UNIVERSITY
    Inventors: Nam-Hai Chua, Shulin Deng, Hongzheng Dai, Qi-Wen Niu, Huan Wang, Catalina Arenas Huertero
  • Publication number: 20150159157
    Abstract: The invention provides methods and compositions useful in target sequence suppression, target sequence validation and target sequence down regulation. The invention provides polynucleotide constructs useful for gene silencing or RNA down regulation, as well as cells, plants and seeds comprising the polynucleotides. The invention also provides a method for using microRNA to silence a target sequence or to down regulate RNA.
    Type: Application
    Filed: February 20, 2015
    Publication date: June 11, 2015
    Applicant: THE ROCKEFELLER UNIVERSITY
    Inventors: Jose L. REYES-TABOADA, Xiuren ZHANG, Takashi SOYANO, Nam-Hai CHUA, Qi-Wen NIU, Shih-Shun LIN
  • Patent number: 8975471
    Abstract: The invention provides methods and compositions useful in target sequence suppression, target sequence validation and target sequence down regulation. The invention provides polynucleotide constructs useful for gene silencing or RNA down regulation, as well as cells, plants and seeds comprising the polynucleotides. The invention also provides a method for using microRNA to silence a target sequence or to down regulate RNA.
    Type: Grant
    Filed: October 12, 2005
    Date of Patent: March 10, 2015
    Assignee: The Rockefeller University
    Inventors: Jose L. Reyes Taboada, Xiuren Zhang, Takashi Soyano, Nam-Hai Chua, Qi-Wen Niu, Shih-Shun Lin
  • Patent number: 8581037
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: November 12, 2013
    Assignee: The Rockefeller University
    Inventors: Jianru Zuo, Qi-Wen Niu, Giovanna Frugis, Nam-Hai Chua
  • Patent number: 8524469
    Abstract: The present invention provides a two-step Gram staining method. The method is conducted by using a clean slide, followed by adding 10˜30 ?l primary stain from a reagent kit, adding an equivalent amount of specimens uniformly on said slide, then immediately adding 30˜60 ?l counter-stain on said slide for incubating 15 seconds, rinsing with water, and finally examining under a microscope, the result appears color contrast on the center of the slide between the Gram-negative bacteria performing light red color and the Gram-positive bacteria performing deep purple color.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: September 3, 2013
    Assignee: Ying Ye
    Inventors: Ying Ye, Tao Yuan, Li-Xin Yang, Feng-Qi Wen
  • Patent number: 8431773
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: April 30, 2013
    Assignee: The Rockefeller University
    Inventors: Jianru Zuo, Qi-Wen Niu, Giovanna Frugis, Nam-Hai Chua