Abstract: Provided are an ionizable lipid compound with an adjacent cis-double bond structure, a preparation method therefor, and the use thereof in the delivery of an active therapeutic agent (e.g., a nucleic acid). The ionizable lipid compound can provide a higher encapsulation rate of active substances and a better cell or in vivo transfection rate, and is particularly suitable for preparing nanoparticles with a solid structure.

Abstract: A thermoplastic composite material has an inner layer material and at least one layer of outer layer material. The inner layer material is a core layer that contains fiber bundles, a first thermoplastic resin and a first auxiliary agent; and the at least one layer of outer layer material wraps the core layer and is a resin layer comprising a second thermoplastic resin and an optional second auxiliary agent. The fiber bundles extend continuously from one end of the core layer to the opposite end thereof. The inner layer-outer layer composite structure improves the processing performance of the thermoplastic composite material and the lubricity between fibers and resin matrixes during injection molding, and improves the fluidity of the fibers in a resin matrix melt.

Abstract: Provided are an ionizable lipid compound with an adjacent cis-double bond structure, a preparation method therefor, and the use thereof in the delivery of an active therapeutic agent (e.g., a nucleic acid). The ionizable lipid compound can provide a higher encapsulation rate of active substances and a better cell or in vivo transfection rate, and is particularly suitable for preparing nanoparticles with a solid structure.

Abstract: A process for the production of a catalyst comprising the steps of: dissolving the requisite quantities of copper nitrate and nickel nitrate in de-ionised water to provide a sub-0.30 molar aqueous solution of copper nitrate and nickel nitrate together in the ratio required; providing an ammoniacal solution by adding concentrated aqueous solution of ammonia in a quantity equal to between six and ten times the quantity required to realise both a 1:6 molar ratio for Cu2+ to ammonia and a 1:6 molar ratio for Ni2+ to ammonia; loading gamma alumina with 1 to 30% w/w of copper and nickel in a weight ratio of nickel to copper of 1:5 to 2:1 by suspending the requisite quantity of gamma alumina in said ammoniacal solution to achieve the required loading of copper and nickel; stirring the resulting gamma alumina suspension for at least 4 h at room temperature; then the volatile components evaporate under ambient conditions leaving dry loaded gamma alumina, which is calcined at a temperature of at least 260° C.

Abstract: A thermoplastic composite material has an inner layer material and at least one layer of outer layer material. The inner layer material is a core layer that contains fiber bundles, a first thermoplastic resin and a first auxiliary agent; and the at least one layer of outer layer material wraps the core layer and is a resin layer comprising a second thermoplastic resin and an optional second auxiliary agent. The fiber bundles extend continuously from one end of the core layer to the opposite end thereof. The inner layer-outer layer composite structure, can effectively improves the processing performance of the thermoplastic composite material and the lubricity between fibers and resin matrixes during injection molding, and improves the fluidity of the fibers in a resin matrix melt.

Abstract: A process for the production of a catalyst comprising the steps of: dissolving the requisite quantities of copper nitrate and nickel nitrate in de-ionised water to provide a sub-0.30 molar aqueous solution of copper nitrate and nickel nitrate together in the ratio required; providing an ammoniacal solution by adding concentrated aqueous solution of ammonia in a quantity equal to between six and ten times the quantity required to realise both a 1:6 molar ratio for Cu2+ to ammonia and a 1:6 molar ratio for Ni2+ to ammonia; loading gamma alumina with 1 to 30% w/w of copper and nickel in a weight ratio of nickel to copper of 1:5 to 2:1 by suspending the requisite quantity of gamma alumina in said ammoniacal solution to achieve the required loading of copper and nickel; stirring the resulting gamma alumina suspension for at least 4 h at room temperature; then the volatile components evaporate under ambient conditions leaving dry loaded gamma alumina, which is calcined at a temperature of at least 260° C.

Abstract: A process for the production of a catalyst comprising the steps of: dissolving the requisite quantities of copper nitrate and nickel nitrate in de-ionised water to provide a sub-0.30 molar aqueous solution of copper nitrate and nickel nitrate together in the ratio required; providing an ammoniacal solution by adding concentrated aqueous solution of ammonia in a quantity equal to between six and ten times the quantity required to realise both a 1:6 molar ratio for Cu2+ to ammonia and a 1:6 molar ratio for Ni2+ to ammonia; loading gamma alumina with 1 to 30% w/w of copper and nickel in a weight ratio of nickel to copper of 1:5 to 2:1 by suspending the requisite quantity of gamma alumina in said ammoniacal solution to achieve the required loading of copper and nickel; stirring the resulting gamma alumina suspension for at least 4 h at room temperature; then the volatile components evaporate under ambient conditions leaving dry loaded gamma alumina, which is calcined at a temperature of at least 260° C.

Abstract: A microscope having three-dimensional imaging capability and a three-dimensional microscopic imaging method are provided, the microscope including: at least one excitation device configured to generate a detectable contrast in a detection target region of a sample which is to be detected, in an excitation principal axis direction; at least one detection device, configured to detect the contrast as generated from the detection target region of the sample in a detection principal axis; and at least one movement mechanism, configured to generate a relative movement of the sample relative to the excitation device and the detection device; the relative movement is in a direction neither parallel to nor perpendicular to the excitation principal axis direction or the detection principal axis direction.

Abstract: A microscope having three-dimensional imaging capability and a three-dimensional microscopic imaging method are provided, the microscope including: at least one excitation device configured to generate a detectable contrast in a detection target region of a sample which is to be detected, in an excitation principal axis direction; at least one detection device, configured to detect the contrast as generated from the detection target region of the sample in a detection principal axis; and at least one movement mechanism, configured to generate a relative movement of the sample relative to the excitation device and the detection device; the relative movement is in a direction neither parallel to nor perpendicular to the excitation principal axis direction or the detection principal axis direction.

Abstract: Methods, systems, and apparatus, including computer program products for identifying optical disc media. In one aspect a method is provided that includes receiving printed information read from an optical media disc. Identifying a media-type of the optical media disc from the printed information. The printed information can be printed on optical media disc in ink. The printed information can be printed on optical media disc which includes a plurality of stripes.