Abstract: The present invention relates to a benzo seven-membered ring bifunctional compound and an application thereof, and in particular to a compound represented by formula (IV) and a pharmaceutically acceptable salt thereof. The compound can be used for preparing a drug for treating diseases related to an estrogen receptor protein degradation targeting chimera.

Abstract: Computer-implemented methods, apparatuses and systems for obtaining data authorization are described. In an example method, a first computing node in a trusted computing center receives an authentication request from a first provider. Authentication information is returned to the first provider, where the authentication information comprises a first code hash of a first computing logic running in the first computing node. A channel establishment request sent by the first provider is received after determining that the first computing node passes trusted authentication and the first code hash passes correctness verification. A first trusted channel is established between the first provider and the first computing node according to the channel establishment request. A target encryption key is received through the first trusted channel, thereby authorization to perform computation on a target encrypted shard corresponding to the target encryption key based on the first computing logic is obtained.

Abstract: A divided-pulse laser regeneration amplification apparatus includes: a signal light coupling component including a first half-wave plate, a first polarization beam splitter, a first Faraday rotator and a second half-wave plate placed in sequence; and a divided-pulse laser regeneration amplification component including a second polarization beam splitter and a third reflector, the second polarization beam splitter is adjacent to the second half-wave plate and is in a same column as the third reflector and the second half-wave plate; a first quarter-wave plate, a Pockels cell and a first reflector are successively arranged on a first side of the second polarization beam splitter, and a third half-wave plate, a first pulse polarization separation component and a first non-linear pulse amplification component are successively arranged on a second side of the second polarization beam splitter.

Abstract: Provided are a salt form and a crystal form of a pyrazole substituted imidazo[1,2-a]quinoxaline derivative, and a preparation method therefor. Specifically disclosed are a salt form and a crystal form of a compound of formula (I), and a preparation method therefor and the use thereof in the preparation of drugs related to dual inhibitors of spleen tyrosine kinase (Syk) and vascular endothelial growth factor 2 (VEGFR2).

Abstract: This invention in one aspect relates to a mixed-kernel heterojunction transistor, comprising a monolayer film formed of an atomically thin material, and a network of carbon nanotubes (CNTs) vertically stacked over the monolayer film to define an overlap region of the CNT network with the monolayer film, and non-overlap regions of the monolayer film and the CNT network, wherein the overlap region is a mixed-kernel van der Waals heterojunction.

Abstract: Embodiments described herein provide enhanced low-density hollow glass bead (HGB) fluids, as well as methods for utilizing such HGB fluids for wellbore drilling operations, completion operations, and workover operations. Such low-density HGB fluids include the following combination of constituents: a base oil, an oil viscosifying agent, HGBs at a concentration in a range between 20 vol % and 60 vol %, an organophilic clay, a clay activator, a surfactant, and (optionally) an H2S scavenger. Moreover, the low-density HGB fluids are suitable for use as lower-density cap fluids for pressurized mudcap drilling (PMCD) operations, alternative drilling fluids for managed pressure drilling (MPD) operations, alternative drilling fluids for conventional drilling operations corresponding to very-low-pressure or highly-depleted reservoirs, and/or lightweight fluids for wellbore workover operations.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a first user equipment (UE) may receive, from a first network node associated with the first UE, a cross-link interference (CLI) configuration. The first UE may transmit, to a second UE, an inter-UE CLI measurement reference signal based at least in part on the CLI configuration, a measurement associated with the inter-UE CLI measurement reference signal being signaled to the first network node. Numerous other aspects are described.

Abstract: A method for reinforcing soft ground by post-grouting combined with pressurized vacuum preloading is proposed, by pre-burying prefabricated vertical drains and air-boosted pipes in granular material piles, and the air-boosted pipes are used as grouting pipes to reduce the number of times of piling, which not only improves the construction efficiency, but also reduces the structural disturbance of the soil and the influence of smear effect, thus reducing the impact on the radial permeability and the radial consolidation coefficients. The method does not use geotextile bags for granular materials, which can avoid the problem of forming a localized clogging area around the geotextile bags, and the method not only improves the efficiency of vacuum transfer in a pre-consolidation stage, but also improves the grouting effect in the later stage, effectively enhances the strength of soft soil and makes granular material piles and the surrounding soil form composite ground.

Abstract: The present disclosure relates to novel compounds that inhibit glucose-induced degradation-deficient (GID) E3 ligase, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.

Abstract: A plasma-facing component of a fusion reactor divertor, including an inner target transition support and a dome transition support which are integrated into an inner target-dome transition support. The inner target-dome transition support and an outer horizontal target transition support are each prepared from two materials. The channel connection inside the inner target-dome transition support and the outer horizontal target transition support is realized through an S-shaped flow channel and a collector box. In V-shaped regions of inner and outer targets, a plasma-facing unit is connected to the collector box in the transition support via a bending tube, and is communicated with a coolant flowing through horizontal and vertical targets through an intermediate flow channel in the transition block. A method of preparing the plasma-facing component is further provided.

Abstract: The invention provides a preparation method of high-content Ganoderma lucidum ?-glucan and an efficient and rapid detection method thereof. The preparation method comprises ethanol-trypsin pretreatment of Ganoderma lucidum fruiting body in combination with ultrasonic-assisted alkaline hydrothermal extraction of ?-glucan from Ganoderma lucidum, and purifying ?-glucan by DEAE Sephadex A-25 Sephadex column chromatography using NAOH solution as a mobile phase, to obtain high purity (?90%) of Ganoderma lucidum ?-glucan. The detection method comprises placing the extracted ?-glucan in an autoclave and performing hydrolysis with ?-(1,3)-exo-glucanase and ?-glucosidase, and detecting and analyzing the content of the prepared ?-glucan by high pressure-acid enzymatic hydrolysis-HPLC method, using glucose as a standard. The preparation method of ?-glucan has high extraction ratio.

Abstract: A high effective refractive index structure may include one or more high effective refractive index materials disposed on a substrate. The high effective refractive index structure configured to respond to a light received at the high effective refractive index structure by at least generating one or more sub-diffraction limit illumination patterns for illuminating a specimen while one or more frames are captured of the illuminated specimen. The one or more sub-diffraction limit illumination patterns may include one or more speckle patterns. The one or more high effective refractive index materials may exhibit an effective refractive index equal to or greater than 3. Examples of high effective refractive index materials include hyperbolic metamaterial (HMM) multilayers, nanowire based hyperbolic metamaterials, and organic hyperbolic materials (OHM).

Abstract: A UE receives information indicating a set of slots or symbols for a subband full duplex (SBFD) operation. The UE also receives a configuration of an SBFD format including at least a first subband for uplink communication and a second subband for downlink communication. The UE further receives an indication that indicates for the UE to update the SBFD format for at least a subset of the set of slots or symbols.

Abstract: The present disclosure provides a method of scheduling for a UE. The method includes dividing M UEs into N groups, wherein a distance metric between each UE in a group and the center of the group does not exceed a first predetermined threshold, where M and N are positive integers; pairing the N groups, wherein a distance metric between centers of the two paired groups is greater than a second predetermined threshold; and in a case where there is a group paired with a group to which a first UE for which scheduling is to be performed belongs, scheduling transmissions in different directions respectively for the first UE and the second UE from the paired group on the same time-frequency resource. The present disclosure also provides a signal transmission method, a base station, a UE and a computer readable medium.

Abstract: According to some embodiments, systems and methods are provided including an automatic testing (AT) framework including an automatic testing (AT) tool and an AT engine; a processing unit coupled to the automatic testing framework to: generate a JSON file, wherein the JSON file is a test case; upload the generated test case to a database of the AT framework; and execute the test case in response to uploading, wherein execution further comprises: reading the test case from the database; validating the JSON file matches a JSON schema; mocking the test case to generate an executable test, including one or more nullable values based on the generated JSON file; executing the executable test to generate an output; and verifying the generated output by comparing the generated output to an expected output in the test case. Numerous other aspects are provided.

Abstract: The present disclosure provides a signal transmission/reception method, user equipment, and network equipment, the method including: determining, by a user equipment, an available random access occasion and a timing advance (TA) value; performing listen before talk (LBT) before a TA of the first available random access occasion; transmitting, if the LBT is successful, the random access preamble on the random access occasion.

Abstract: Systems, apparatuses, and methods to mitigate effects of glitch attacks on a broadcast communication bus are provided. The voltage levels of the communication bus are repeatedly sampled to identify glitch attacks. The voltage level on the communication bus can be overdriven or overwritten to either corrupt received messages or correct received messages.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for false detection removal using adversarial masks. The method includes performing object detection on a first image that includes a first region using a detection model determining the detection model incorrectly classified the first region of the first image; generating an adversarial mask based on the first region of the first image and the detection model; obtaining a second image that includes the first region; generating a masked image based on the second image and the adversarial mask; and performing object detection on the masked image including the first region using the detection model.

Abstract: A quantitative source apportionment method based on nontarget high-resolution mass spectrometry (HRMS) data of pollution sources and pollution receptors includes: acquiring samples of pollution sources and receptors, pre-processing samples to extract trace organic pollutants; acquiring chromatography-HRMS nontarget data; pre-processing raw data to obtain a HRMS dataset including a mass-to-charge ratio, a retention time, and a peak area; determining a source-sink relationship based on positions of pollution sources and receptors; constructing an input matrix by combining the HRMS dataset and using each sink as a group; adopting an expectation-maximization method or a Bayesian method to calculate contribution of each source based on a standardized input matrix. Beneficial effects at least include the follows.