Patents by Inventor Qian Du

Qian Du has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250059225
    Abstract: The present disclosure provides a method for preparing stachyose, which method belongs to the technical field of the production of carbohydrates. The method includes: breaking the wall of Stachys affinis; subjecting the resulting wall-broken material to filter pressing to obtain a filtrate and filter residues; decoloring the filtrate to obtain a decolored liquid; filtering the decolored liquid with a nanofiltration membrane to obtain a nanofiltration liquid; subjecting the nanofiltration liquid to a mixed bed ion exchange treatment to obtain an exchanged liquid; purifying the exchanged liquid by means of continuous simulated moving bed chromatography to obtain a purified liquid; and concentrating and vacuum drying the purified liquid to obtain stachyose.
    Type: Application
    Filed: December 27, 2022
    Publication date: February 20, 2025
    Applicant: SHANDONG BAILONG CHUANGYUAN BIO-TECH CO., LTD
    Inventors: Qian DU, Lingling CHEN, Jianjin Dong, Xianbao SHAO, Guoqing LIU
  • Publication number: 20250023209
    Abstract: A battery includes a housing, a plurality of cells disposed inside the housing, and a set of strap structures. Each cell comprises a plurality of positive electrode plates and a plurality of negative electrode plates, and each respective electrode plate has a respective tip. The set of strap structures includes one or more of a first strap structure, which includes a positive strap line, a negative strap line, and at least two bridging lines disposed between and connected with the positive strap line and the negative strap line. The negative strap line is connected with respective tips of a plurality of negative electrode plates in a cell. The positive strap line is connected with respective tips of a plurality of positive electrode plates in a different cell. The first strap structure, the set of strap structure, and a method of making the battery are also provided.
    Type: Application
    Filed: July 12, 2024
    Publication date: January 16, 2025
    Applicant: Trojan Battery Company, LLC
    Inventors: Chen Tang, Qian Du, Haitao Zhou, Xingyu Zhang
  • Publication number: 20240390329
    Abstract: An application of a channel blocker in preparation of drugs for treating and/or preventing liver fibrosis is provided, belonging to the field of biomedical technology. A new use of phenytoin sodium is provided. It is demonstrated that at the cell level, the phenytoin sodium can improve liver fibrosis by regulating autophagy and thus affecting the activation of hepatic stellate cells. In this situation, the efficacy of the phenytoin sodium on liver fibrosis is verified at the animal level by establishing a disease model, and the phenytoin sodium can be used to prepare drugs for treating and/or preventing liver fibrosis.
    Type: Application
    Filed: September 6, 2023
    Publication date: November 28, 2024
    Inventors: Rui Xie, Jingyu Xu, Guowei Gong, Qian Du, Yanxia Hu, Jianhong Ding, Xianli Wu, Xiaoxu Yang, Jun Lou, Qi Liu, Zhuo Li
  • Publication number: 20240390395
    Abstract: An ion channel blocker for treatment and/or prevention of hepatic fibrosis is provided. Based on the fact that the activation of hepatic stellate cells is an important link in anti-hepatic fibrosis, it is found that gliclazide has the effect of inhibiting the activation of hepatic stellate cells by in vitro and in vivo experiments. Further exploration reveals that gliclazide mainly inhibits the activation of hepatic stellate cells by inhibiting autophagy pathways, and thus the gliclazide can be used to prepare medicaments for treatment and/or prevention of hepatic fibrosis.
    Type: Application
    Filed: September 14, 2023
    Publication date: November 28, 2024
    Inventors: Jingyu Xu, Rui Xie, Qian Du, Yanxia Hu, Jianhong Ding, Xianli Wu, Xiaoxu Yang, Jun Lou, Qi Liu, Zhuo Li
  • Publication number: 20240390308
    Abstract: An application of potassium ion (K+) channel blocker in preparation of drugs for treating liver fibrosis is provided, which relates to the field of medical technologies. The K+ channel blocker is sotalol, the sotalol is originally used as an antiarrhythmic drug in clinic and has a property of inhibiting K+ channels. Experiments show that sotalol can effectively inhibit liver fibrosis and reduce expression of fibrosis-related protein alpha-smooth muscle actin (?-SMA), specifically by regulating expression and/or function of autophagy and epithelial-mesenchymal transition (EMT) molecules to achieve inhibition of hepatic stellate cell (HSC) fibrosis, so as to provide a new drug choice for clinical treatment of the liver fibrosis.
    Type: Application
    Filed: July 6, 2023
    Publication date: November 28, 2024
    Inventors: Rui Xie, Jingyu Xu, Qian Du, Yanxia Hu, Jianhong Ding, Xianli Wu, Xiaoxu Yang, Jun Lou, Qi Liu, Zhuo Li
  • Publication number: 20240370307
    Abstract: Dynamic adjusting of pod resource limits is provided at runtime of a container orchestration platform pod. The process includes deploying a container orchestration platform pod with one or more pod resources in a computing environment, where the pod resources have one or more associated pod resource limits. Further, the process includes monitoring a runtime resource usage of the container orchestration platform pod, and predicting, by a trained machine learning model, upcoming resource usage of the container orchestration platform pod. The predicting uses, at least in part, the monitored runtime resource usage. Further, the process includes dynamically adjusting a pod resource limit of the one or more pod resource limits of the container orchestration platform pod in the computing environment. The dynamically adjusting is based on the monitored runtime resource usage, and the predicted upcoming resource usage.
    Type: Application
    Filed: May 5, 2023
    Publication date: November 7, 2024
    Inventors: Jing YOU, Kun YANG, Peng Hui JIANG, Sushma HIREMATH, Qian DU, Amit ANAND, Khushboo SINGH, Kumari MUKTTA
  • Publication number: 20240336705
    Abstract: The present application relates to a method for preparing resistant dextrin, and belongs to the technical field deep processing of starch. By means of the present disclosure, proteins are firstly removed from starch milk, and then hydrolysis, evaporation concentration, polymerization, refining and purification are sequentially carried out to finally obtain a resistant dextrin, and by means of controlling the content of proteins in the starch milk, Maillard reaction is effectively reduced, the content of dietary fibers in a crude product and the light transmittance of a product are increased, the sharing of subsequent refining and purification is reduced, the consumption of activated carbon and acid and alkali is reduced, and the cost of refining and purification is reduced.
    Type: Application
    Filed: November 7, 2022
    Publication date: October 10, 2024
    Applicant: SHANDONG BAILONG CHUANGYUAN BIO-TECH CO., LTD.
    Inventors: Zhaobo GAN, Qian DU, Mingzhan ZHANG, Shuangshuang LIU
  • Patent number: 11780870
    Abstract: The present application relates to a method for preparing crystalline D-psicose. In the present application, crystalline D-psicose is prepared by means of combining an evaporative crystallization method and a cooling crystallization method, so that the preparation process is simple, the operation is easy, and the crystallization period is short. In the present application, a seed crystal is added when the solid content is relatively low (70-75%) in an evaporative crystallization process, so that the crystallization process is facilitated, the growth speed of the crystal in each direction is more uniform, the whole crystallization period can be shortened, and the energy consumption is reduced; and after the evaporative crystallization is finished, crystal regulation is carried out, so that the crystal size tends to be equalized, the crystal surface grows to be smooth, and the crystal form is perfected.
    Type: Grant
    Filed: December 3, 2021
    Date of Patent: October 10, 2023
    Assignee: SHANDONG BAILONG CHUANGYUAN BIO-TECH CO., LTD.
    Inventors: Zhaobo Gan, Xianbao Shao, Fanghua Li, Qian Du, Xingjing Zhang, Shuangshuang Liu
  • Publication number: 20230287026
    Abstract: The present application relates to a method for preparing crystalline D-psicose. In the present application, crystalline D-psicose is prepared by means of combining an evaporative crystallization method and a cooling crystallization method, so that the preparation process is simple, the operation is easy, and the crystallization period is short. In the present application, a seed crystal is added when the solid content is relatively low (70-75%) in an evaporative crystallization process, so that the crystallization process is facilitated, the growth speed of the crystal in each direction is more uniform, the whole crystallization period can be shortened, and the energy consumption is reduced; and after the evaporative crystallization is finished, crystal regulation is carried out, so that the crystal size tends to be equalized, the crystal surface grows to be smooth, and the crystal form is perfected.
    Type: Application
    Filed: December 3, 2021
    Publication date: September 14, 2023
    Applicant: SHANDONG BAILONG CHUANGYUAN BIO-TECH CO., LTD.
    Inventors: Zhaobo GAN, Xianbao SHAO, Fanghua LI, Qian DU,, Xingjing ZHANG, Shuangshuang LIU
  • Publication number: 20220186272
    Abstract: The invention relates to a strain of Trichoderma reesei BLCY-007 and its application in the production of xylooligosaccharides.
    Type: Application
    Filed: July 6, 2020
    Publication date: June 16, 2022
    Inventors: Baode DOU, Guangpeng DOU, Zhaobo GAN, Xianbao SHAO, Fanghua LI, Qian DU
  • Patent number: 11279961
    Abstract: Provided are an Aspergillus oryzae BLCY-006 strain and an application thereof in the preparation of a galactooligosaccharide. The strain produces ?-galactosidase, and the enzyme activity can reach 300 U/ml after culturing and fermentation, which is more than 50% higher than traditional ?-galactosidase activity. The enzyme also has lactose and glucose resistance properties.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: March 22, 2022
    Assignee: SHANDONG BAILONG CHUANGYUAN BIO-TECH CO., LTD
    Inventors: Fanghua Li, Zhaobo Gan, Guangpeng Dou, Xianbao Shao, Mingzhan Zhang, Qian Du, Tengteng Yang
  • Patent number: 11149048
    Abstract: A method for preparing high-purity D-psicose, comprising the following steps: (1) centrifuging a fermentation broth of Bacillus subtilis, and then subjecting the bacteria to homogenization to obtain a mixed solution containing D-psicose 3-epimerase; (2) preparing a fructose solution, adding the mixed solution containing D-psicose 3-epimerase to the fructose solution, adjusting the pH, adding cobalt chloride thereto, and performing the reaction at a certain temperature; and feeding the fructose solution to the reaction solution, continuing the reaction, and stopping the reaction, obtaining a crude D-psicose solution; and (3) subjecting the crude D-psicose solution to decolorization, filtration, ion exchange, chromatographic separation, concentration, and then crystallization or drying, obtaining D-psicose.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: October 19, 2021
    Assignee: SHANDONG BAILONG CHUANGYUAN BIO-TECH CO., LTD
    Inventors: Baode Dou, Guangpeng Dou, Mingzhan Zhang, Xianbao Shao, Fanghua Li, Qian Du, Tengteng Yang
  • Publication number: 20210139938
    Abstract: Provided are an aspergillus oryzae BLCY-006 strain and an application thereof in the preparation of a galactooligosaccharide. The strain produces ?-galactosidase, and the enzyme activity can reach 300 U/ml after culturing and fermentation, which is more than 50% higher than traditional ?-galactosidase activity. The enzyme also has lactose and glucose resistance properties.
    Type: Application
    Filed: February 18, 2020
    Publication date: May 13, 2021
    Inventors: Zhaobo GAN, Fanghua LI, Guangpeng DOU, Xianbao SHAO, Mingzhan ZHANG, Qian DU, Tengteng YANG
  • Patent number: 10968424
    Abstract: A Bacillus subtilis strain or a progeny thereof, a method of culturing the same and uses thereof. The invention also relates to a culture and lysate of the Bacillus subtilis strain or its progeny, and a method for producing D-psicose epimerase and producing D-psicose using the Bacillus subtilis strain or its progeny.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: April 6, 2021
    Assignee: SHANDONG BAILONG CHUANGYUAN BIO-TECH CO., LTD
    Inventors: Guangpeng Dou, Xianbao Shao, Qian Du, Zhaobo Gan, Fanghua Li, Mingzhan Zhang, Tengteng Yang, Shuangshuang Liu
  • Publication number: 20200062792
    Abstract: A method for preparing high-purity D-psicose, comprising the following steps: (1) centrifuging a fermentation broth of Bacillus subtilis, and then subjecting the bacteria to homogenization to obtain a mixed solution containing D-psicose 3-epimerase; (2) preparing a fructose solution, adding the mixed solution containing D-psicose 3-epimerase to the fructose solution, adjusting the pH, adding cobalt chloride thereto, and performing the reaction at a certain temperature; and feeding the fructose solution to the reaction solution, continuing the reaction, and stopping the reaction, obtaining a crude D-psicose solution; and (3) subjecting the crude D-psicose solution to decolorization, filtration, ion exchange, chromatographic separation, concentration, and then crystallization or drying, obtaining D-psicose.
    Type: Application
    Filed: December 1, 2017
    Publication date: February 27, 2020
    Inventors: Baode DOU, Guangpeng DOU, Mingzhan ZHANG, Xianbao SHAO, Fanghua LI, Qian DU, Tengteng YANG
  • Patent number: 10479840
    Abstract: A resistant dextrin and a method for preparing the same. In the resistant dextrin, molar content of DP1 is smaller than or equal to 1%, molar content of DP2 is smaller than or equal to 4.5%, molar content of DP3 is smaller than or equal to 7.0%, an average degree of polymerization is 6-12, a pH value is 3.0-6.0, and molar content of dietary fibers is greater than or equal to 85%. The present invention further relates to a method for preparing the resistant dextrin. Since the present invention uses starch as the raw material and divides dextrinization reaction into two stages for the first time, the degree of polymerization of the polymerization reaction is reliably guaranteed, the number of caused side reactions is decreased at the same time and the difficulty in subsequent purification treatment is greatly decreased.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: November 19, 2019
    Assignee: SHANDONG BAILONG CHUANGYUAN BIO-TECH CO., LTD
    Inventors: Guangpeng Dou, Zhaobo Gan, Fanghua Li, Xianbao Shao, Tengteng Yang, Qian Du, Mingzhan Zhang, Xingjing Zhang
  • Publication number: 20190284521
    Abstract: A Bacillus subtilis strain or a progeny thereof, a method of culturing the same and uses thereof. The invention also relates to a culture and lysate of the Bacillus subtilis strain or its progeny, and a method for producing D-psicose epimerase and producing D-psicose using the Bacillus subtilis strain or its progeny.
    Type: Application
    Filed: November 28, 2017
    Publication date: September 19, 2019
    Inventors: Guangpeng DOU, Xianbao SHAO, Qian DU, Zhaobo GAN, Fanghua LI, Mingzhan ZHANG, Tengteng YANG, Shuangshuang LIU
  • Publication number: 20180094082
    Abstract: A resistant dextrin and a method for preparing the same. In the resistant dextrin, molar content of DP1 is smaller than or equal to 1%, molar content of DP2 is smaller than or equal to 4.5%, molar content of DP3 is smaller than or equal to 7.0%, an average degree of polymerization is 6-12, a pH value is 3.0-6.0, and molar content of dietary fibers is greater than or equal to 85%. The present invention further relates to a method for preparing the resistant dextrin. Since the present invention uses starch as the raw material and divides dextrinization reaction into two stages for the first time, the degree of polymerization of the polymerization reaction is reliably guaranteed, the number of caused side reactions is decreased at the same time and the difficulty in subsequent purification treatment is greatly decreased.
    Type: Application
    Filed: January 17, 2017
    Publication date: April 5, 2018
    Inventors: Guangpeng DOU, Zhaobo QIAN, Fanghua LI, Xianbao SHAO, Tengteng YANG, Qian DU, Mingzhan ZHANG, Xingjing ZHANG
  • Patent number: 9706019
    Abstract: A method, a system, and a network element for service processing after data of a network element is invalid or a network element fails are provided. When the service network element (1) receives the service request message from the network and initiated to a called end and the user data is invalid, the service network element (1) returns a data invalid message of the called end to the network. When a network element containing registration data of a user is abnormal and the registration data of the user is invalid, by using the present invention, the service unavailable time is shortened, and user services can be recovered rapidly.
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: July 11, 2017
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Qian Du, Bing Wei, Xiaoyun Wang, Leibin Wang, Shufeng Shi, Peng Zhao, Xuexia Yan
  • Patent number: 8346271
    Abstract: The present invention relates a method for implementing a business of communication service level based on a user request.
    Type: Grant
    Filed: February 6, 2006
    Date of Patent: January 1, 2013
    Assignee: China Mobile Communications Corporation
    Inventors: Congxing Ouyang, Bing Wei, Qian Du