Patents by Inventor Qian Ma

Qian Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220186271
    Abstract: The present disclosure relates to the field of genetic engineering, especially relates to a xylose-induced genetically engineered bacteria used for producing ectoine as well as a construction method and use thereof The genetically engineered bacteria is constructed by heterologously expressing the ectABC gene cluster from Halomonas elongata on the E. coli chromosome, using the promoter of xylose transporter coding gene xylF to control the RNA polymerase from T7 bacteriophage, reconstructing a synthesis pathway of ectoine and constructing a plasmid-free system, and enhancing the expression of target genes by a strong promoter T7; the yiled of ectoine reached 12-16 g/L after 20-28 h fermentation in shake flask, and reached 35-50 g/L after 24-40 h fermentation in a 5 L fermentor.
    Type: Application
    Filed: June 14, 2017
    Publication date: June 16, 2022
    Inventors: Xixian XIE, Xuejiao WU, Ning CHEN, Fangqing YAN, Qian MA, Jie MA, Hongchao ZHANG
  • Patent number: 11287444
    Abstract: Disclosed is an atomic force microscopy system includes a laser source configured to generate an optical probe beam containing light of different spectral light components at different optical wavelengths, a dispersive optical device positioned to receive the optical probe beam and configured to disperse the optical probe beam into different dispersed light beams that are at different optical wavelengths and are spatially separated from one another, a cantilever array including a plurality of cantilevers structured to detect a sample and configured to deflect the different dispersed light beams by moving in position based on an interaction with the sample to produce multiple deflected output beams at different output optical wavelengths from the cantilevers, and a plurality of photodetectors to receive the multiple deflected output beams of different wavelengths from the cantilevers, respectively.
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: March 29, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Ratneshwar Lal, Qingqing Yang, Qian Ma, Zhaowei Liu
  • Patent number: 11239331
    Abstract: A thin film transistor substrate and a method of fabricating same are provided. The thin film transistor substrate includes a substrate, a light shielding layer disposed on the substrate, a buffer layer disposed on the light shielding layer, an active layer disposed on the buffer layer, and a gate insulating layer disposed on the active layer. The gate insulating layer includes a stacked structure including a first insulating layer and a second insulating layer.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: February 1, 2022
    Inventors: Qian Ma, Xingyu Zhou
  • Publication number: 20210396783
    Abstract: Disclosed is an atomic force microscopy system includes a laser source configured to generate an optical probe beam containing light of different spectral light components at different optical wavelengths, a dispersive optical device positioned to receive the optical probe beam and configured to disperse the optical probe beam into different dispersed light beams that are at different optical wavelengths and are spatially separated from one another, a cantilever array including a plurality of cantilevers structured to detect a sample and configured to deflect the different dispersed light beams by moving in position based on an interaction with the sample to produce multiple deflected output beams at different output optical wavelengths from the cantilevers, and a plurality of photodetectors to receive the multiple deflected output beams of different wavelengths from the cantilevers, respectively.
    Type: Application
    Filed: October 8, 2019
    Publication date: December 23, 2021
    Inventors: Ratneshwar Lal, Qingqing Yang, Qian Ma, Zhaowei Liu
  • Publication number: 20210336018
    Abstract: A thin film transistor substrate and a method of fabricating same are provided. The thin film transistor substrate includes a substrate, a light shielding layer disposed on the substrate, a buffer layer disposed on the light shielding layer, an active layer disposed on the buffer layer, and a gate insulating layer disposed on the active layer. The gate insulating layer includes a stacked structure including a first insulating layer and a second insulating layer.
    Type: Application
    Filed: October 24, 2019
    Publication date: October 28, 2021
    Applicant: Shenzhen China Star Optoelectronics Semiconductor Display Technology Co., Ltd.
    Inventors: Qian MA, Xingyu ZHOU
  • Publication number: 20210328072
    Abstract: A preparation method of a thin film transistor (TFT) array substrate includes a step of providing a substrate to prepare a light shielding layer and a buffer layer in sequence on the substrate; and a step of preparing an active layer, a gate insulation layer, a gate, an interlayer insulation layer, and a source/drain metal layer in sequence on the buffer layer; wherein a light absorption layer is prepared on one side of the active layer. Absorbing light prevents most of the light from being reflected to the active layer by disposing a black photoresist below a source and a drain or over the light shielding layer, thereby improving performance of TFT devices.
    Type: Application
    Filed: April 24, 2019
    Publication date: October 21, 2021
    Applicant: Shenzhen China Star Optoelectronics Semiconductor Display Technology Co., Ltd.
    Inventor: Qian MA
  • Patent number: 11124780
    Abstract: The present disclosure relates to a genetically engineered strain with high production of uridine and its construction method and application. The strain was constructed as follows: heterologously expressing pyrimidine nucleoside operon sequence pyrBCAKDFE (SEQ ID NO:1) on the genome of E coli prompted by strong promoter Ptrc to reconstruct the pathway of uridine synthesis; overexpressing the autologous prsA gene coding PRPP synthase by integration of another copy of prsA gene promoted by strong promoter Ptrc on the genome; deficiency of uridine kinase, uridine phosphorylase, ribonucleoside hydrolase, homoserine dehydrogenase I and ornithine carbamoyltransferase. When the bacteria was used for producing uridine, 40-67 g/L uridine could be obtained in a 5 L fermentor after fermentation for 40-70 h using the technical scheme provided by the disclosure with the maximum productivity of 0.15-0.25 g uridine/g glucose and 1.
    Type: Grant
    Filed: May 12, 2019
    Date of Patent: September 21, 2021
    Assignee: Tianjin University of Science and Technology
    Inventors: Xixian Xie, Ning Chen, Heyun Wu, Guoliang Li, Qiang Li, Xiaoguang Fan, Qingyang Xu, Chenglin Zhang, Yanjun Li, Qian Ma
  • Publication number: 20210171773
    Abstract: The present disclosure describes protein-based resin compositions. In particular, the compositions employ methacrylated or acrylated protein, a strengthening agent, a plasticizer, and an initiator. The protein-based resin compositions may be used for making solid articles that are biodegradable and possess a high degree of tensile strength and water resistance. Methods of preparing the biodegradable protein-based plastic articles are also disclosed.
    Type: Application
    Filed: December 4, 2020
    Publication date: June 10, 2021
    Inventors: LONG JIANG, QIAN MA
  • Publication number: 20210145747
    Abstract: A cerasome delivery system for targeting activated cd44 molecule, a preparation method and use thereof: a surface of a cerasome is partially modified by a targeting ligand, the targeting ligand being a ligand which may specifically bind to an activated cd44 molecule. The cerasome delivery system may be used for the diagnosis, prevention and treatment of vulnerable plaque or diseases associated with vulnerable plaque.
    Type: Application
    Filed: April 12, 2018
    Publication date: May 20, 2021
    Applicant: Beijing Inno Medicine Co., Ltd.
    Inventors: Qian Ma, Jiefang Sun
  • Patent number: 10956338
    Abstract: A technique for improving performance of a cache is provided. The technique involves maintaining indicators of whether cache entries are dirty in a random access memory (“RAM”) that has a lower latency to a cache controller than the cache memory that stores the cache entries. When a request to invalidate one or more cache entries is received by the cache controller, the cache controller checks the RAM to determine whether any cache entries are dirty and thus should be written out to a backing store. Using the RAM removes the need to check the actual cache memory for whether cache entries are dirty, which reduces the latency associated with performing such checks and thus with performing cache invalidations.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: March 23, 2021
    Assignee: ATI Technologies ULC
    Inventors: Leon King Nok Lai, Qian Ma, Jimshed B. Mirza
  • Patent number: 10915359
    Abstract: A technique for scheduling processing tasks having different latencies is provided. The technique involves identifying one or more available requests in a request queue, where each request queue corresponds to a different latency. A request arbiter examines a shift register to determine whether there is an available slot for the one or more requests. A slot is available for a request if there is a slot that is a number of slots from the end of the shift register equal to the number of cycles the request takes to complete processing in a corresponding processing pipeline. If a slot is available, the request is scheduled for execution and the slot is marked as being occupied. If a slot is not available, the request is not scheduled for execution on the current cycle. On transitioning to a new cycle, the shift register is shifted towards its end and the technique repeats.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: February 9, 2021
    Assignee: ATI Technologies ULC
    Inventors: Jimshed B. Mirza, Qian Ma, Leon King Nok Lai
  • Publication number: 20200397926
    Abstract: A liposomal nanocarrier delivery system for targeting an active CD44 molecule, preparation method therefor, and uses thereof. The surface of the liposome is partially modified by a targeting ligand, wherein the targeting ligand is a ligand that can be specifically combined with the active CD44 molecule. The liposomal nanocarrier delivery system can be used for diagnosing, preventing, and treating vulnerable plaque or diseases related to vulnerable plaque.
    Type: Application
    Filed: January 21, 2019
    Publication date: December 24, 2020
    Inventors: Qian Ma, Jiefang Sun
  • Patent number: 10852189
    Abstract: A spectrometry system may include an etalon array having a first etalon and a second etalon. The first etalon may be configured to process light to at least generate a first transmission pattern. The first transmission pattern may have at least a first transmission peak corresponding to a first wavelength in an original spectrum of the light. The second etalon may be configured to process the light to at least generate a second transmission pattern. The second transmission pattern may have at least a second transmission peak corresponding to a second wavelength in the original spectrum of the light. The first etalon may have a different thickness than the second etalon in order for the first transmission pattern to have at least one transmission peak that is at a different wavelength than the second transmission pattern. The first transmission pattern and the second transmission pattern may enable a reconstruction the original spectrum of the light.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: December 1, 2020
    Assignee: The Regents of the University of California
    Inventors: Zhaowei Liu, Qian Ma, Eric Huang
  • Publication number: 20200167076
    Abstract: A technique for improving performance of a data compression system is provided. The technique is applicable to compressed data sets that include compression blocks. Each compression block may be either compressed or uncompressed. Metadata indicating whether compression blocks are actually compressed or not is stored. If compression blocks are not compressed, then a read-decompress-modify-compress-write pipeline is bypassed. Instead, a compression unit writes the data specified by the partial request into the compression block, without reading, decompressing, modifying, recompressing, and writing the data, resulting in a much faster operation.
    Type: Application
    Filed: November 26, 2018
    Publication date: May 28, 2020
    Applicant: ATI Technologies ULC
    Inventors: Leon King Nok Lai, Qian Ma, Jimshed B. Mirza
  • Publication number: 20200167287
    Abstract: A technique for prefetching data for a cache is provided. The technique includes detecting access to a data block. In response to the detection, a prefetch block generates proposed blocks for prefetch. The prefetch block also examines prefetch tracking data to determine whether a prefetch group including the proposed blocks is marked as already having been prefetched. If the group has been marked as already having been prefetched, then then prefetch block does not prefetch that data, thereby avoiding traffic between the prefetch block and the cache memory. Using this technique, unnecessary requests to prefetch data into the cache memory are avoided.
    Type: Application
    Filed: November 26, 2018
    Publication date: May 28, 2020
    Applicant: ATI Technologies ULC
    Inventors: Leon King Nok Lai, Qian Ma, Jimshed B. Mirza
  • Patent number: 10664403
    Abstract: A technique for prefetching data for a cache is provided. The technique includes detecting access to a data block. In response to the detection, a prefetch block generates proposed blocks for prefetch. The prefetch block also examines prefetch tracking data to determine whether a prefetch group including the proposed blocks is marked as already having been prefetched. If the group has been marked as already having been prefetched, then prefetch block does not prefetch that data, thereby avoiding traffic between the prefetch block and the cache memory. Using this technique, unnecessary requests to prefetch data into the cache memory are avoided.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: May 26, 2020
    Assignee: ATI Technologies ULC
    Inventors: Leon King Nok Lai, Qian Ma, Jimshed B. Mirza
  • Publication number: 20200159664
    Abstract: A technique for improving performance of a cache is provided. The technique involves maintaining indicators of whether cache entries are dirty in a random access memory (“RAM”) that has a lower latency to a cache controller than the cache memory that stores the cache entries. When a request to invalidate one or more cache entries is received by the cache controller, the cache controller checks the RAM to determine whether any cache entries are dirty and thus should be written out to a backing store. Using the RAM removes the need to check the actual cache memory for whether cache entries are dirty, which reduces the latency associated with performing such checks and thus with performing cache invalidations.
    Type: Application
    Filed: November 19, 2018
    Publication date: May 21, 2020
    Applicant: ATI Technologies ULC
    Inventors: Leon King Nok Lai, Qian Ma, Jimshed B. Mirza
  • Publication number: 20200159581
    Abstract: A technique for scheduling processing tasks having different latencies is provided. The technique involves identifying one or more available requests in a request queue, where each request queue corresponds to a different latency. A request arbiter examines a shift register to determine whether there is an available slot for the one or more requests. A slot is available for a request if there is a slot that is a number of slots from the end of the shift register equal to the number of cycles the request takes to complete processing in a corresponding processing pipeline. If a slot is available, the request is scheduled for execution and the slot is marked as being occupied. If a slot is not available, the request is not scheduled for execution on the current cycle. On transitioning to a new cycle, the shift register is shifted towards its end and the technique repeats.
    Type: Application
    Filed: November 19, 2018
    Publication date: May 21, 2020
    Applicant: ATI Technologies ULC
    Inventors: Jimshed B. Mirza, Qian Ma, Leon King Nok Lai
  • Patent number: 10576512
    Abstract: The application discloses an improved wheel pretreatment rack. The wheel pretreatment rack includes a hook, tripods, positioning slide blocks, positioning holes, a main rod, bearing rods, braces and positioning clamping jaws. Compared with the traditional wheel pretreatment rack, the improved wheel pretreatment rack in use has the advantages that the requirement of wheels having different sizes for the pretreatment rack is met by adjusting the positions of the bearing rods up and down, and the problems of drop, scratch and the like in the cleaning pretreatment process of the wheel may be effectively prevented by a wheel three-point-fixing mode.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: March 3, 2020
    Assignee: CITIC DICASTAL CO., LTD
    Inventors: Qian Ma, Le Zhang, Yunpeng Du, Chuan Li, Shi Wang
  • Patent number: 10571672
    Abstract: An apparatus for compressive sensing may include a filter array, a detector, and a reconstruction engine. The filter array may be configured to generate a first illumination pattern in response to a first wavelength of light and a second illumination pattern in response to a second wavelength of light. The first illumination pattern and the second illumination pattern may be projected onto an object. The detector may be configured to determine a first intensity of a first light emitted by the object in response to the first illumination pattern and a second intensity of a second light emitted by the object in response to the second illumination pattern. The reconstruction engine may be configured to generate an image of the object based at least on the first intensity, the first illumination pattern, the second intensity, and the second illumination pattern.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: February 25, 2020
    Assignee: The Regents of the University of California
    Inventors: Zhaowei Liu, Eric Huang, Qian Ma