Abstract: A device and method for preparing a fully granular cigarette/filter rod, and a prepared fully granular cigarette/filter rod are disclosed. In certain embodiments, negative pressure is used to adhere granular material onto a mesh-type conveyor belt. The granular material is preliminarily formed into fully granular cigarette/filter rod material by means of a pre-forming apparatus; the fully granular cigarette/filter rod material, traveling with the mesh-type conveyor belt, enters into a forming cavity, and undergoes heating and humidifying treatment, and a continuous solid porous substance is formed; the continuous solid porous substance is moved into the cooling/drying cavity, drying and cooling treatment are performed under the action of negative pressure, and a fully granular cigarette/filter rod with strong adhesion, porosity, permeability, and appropriate moisture is obtained.

Abstract: A strong FXR small-molecule agonist, and a preparation method therefor and use thereof, the structure of the agonist being represented by formula (I), are provided. In the formula, each substituent is as defined in the description and the claims. The compound provided has the advantages of high FXR agonist activity, simple synthesis, easily available raw materials and the like, and can be used for preparing medicines for treating FXR related diseases.

Abstract: The present disclosure relates to a fused ring pyrimidine amino compound and a preparation method, a pharmaceutical composition, and a use thereof. Specifically disclosed in the present disclosure are the compound shown in formula I, a pharmaceutically acceptable salt thereof, a tautomer thereof, a stereoisomer thereof, a metabolite thereof, a metabolic precursor thereof, or a prodrug thereof. The fused ring pyrimidine amino compound of the present application has good inhibitory activity against DDRs, particularly DDR2, and has a good therapeutic effect on tumors and fibrotic diseases, especially pulmonary inflammation and pulmonary fibrosis. Also disclosed in the present disclosure are a preparation method for the compound shown in formula I, and a use thereof.

Abstract: The present disclosure relates to a fused ring pyrimidine amino compound and a preparation method, a pharmaceutical composition, and a use thereof. Specifically disclosed in the present disclosure are the compound shown in formula I, a pharmaceutically acceptable salt thereof, a tautomer thereof, a stereoisomer thereof, a metabolite thereof, a metabolic precursor thereof, or a prodrug thereof. The fused ring pyrimidine amino compound of the present application has good inhibitory activity against DDRs, particularly DDR2, and has a good therapeutic effect on tumors and fibrotic diseases, especially pulmonary inflammation and pulmonary fibrosis. Also disclosed in the present disclosure are a preparation method for the compound shown in formula I, and a use thereof.

Abstract: An FXR small molecule agonist and a preparation method therefor and a use thereof, having a structure as shown in formula (I). The compound represented by formula (I) has FXR agonistic activity and is capable of preparing drugs for treatment of FXR-related diseases.

Abstract: An array substrate, a method of manufacturing the same, and a display device are provided. The array substrate includes a base substrate; a plurality of thin film transistors on the base substrate; and a plurality of light shielding layers on a side of the plurality of thin film transistors facing away from the base substrate, each thin film transistor includes an active layer, at least a portion of the active layer serves as a channel of the thin film transistor, and an orthogonal projection of each of the light shielding layers on the base substrate at least partially overlaps an orthogonal projection of the channel of one of the plurality of thin film transistors on the base substrate.

Abstract: An array substrate, a method of manufacturing the same, and a display device are provided. The array substrate includes a base substrate; a plurality of thin film transistors on the base substrate; and a plurality of light shielding layers on a side of the plurality of thin film transistors facing away from the base substrate, each thin film transistor includes an active layer, at least a portion of the active layer serves as a channel of the thin film transistor, and an orthogonal projection of each of the light shielding layers on the base substrate at least partially overlaps an orthogonal projection of the channel of one of the plurality of thin film transistors on the base substrate.

Abstract: A polymer with alternating phenylene silicon and siloxane structure and a method of producing a precursor of the same are introduced to develop an autonomous synthesis process for para-phenylene disilanol monomer compounds and design a technique of purifying the polymer with alternating phenylene silicon and siloxane structure easily, so as to enable mass production of the polymer with alternating phenylene silicon and siloxane structure.

Abstract: A polymer with alternating phenylene silicon and siloxane structure and a method of producing a precursor of the same are introduced to develop an autonomous synthesis process for para-phenylene disilanol monomer compounds and design a technique of purifying the polymer with alternating phenylene silicon and siloxane structure easily, so as to enable mass production of the polymer with alternating phenylene silicon and siloxane structure.

Abstract: A control method, and an input device of a touch screen terminal are provided. A first touch signal that is input, on a touch screen, by a user by using at least one physical key is received, where the at least one physical key is fixed in a specified area on the touch screen; a second touch signal corresponding to the first touch signal is obtained according to a preset correspondence between the first touch signal and the second touch signal, so that control information can be generated according to the second touch signal, and a control operation is performed. Because the physical key is fixed on the touch screen, the physical key protrudes from the touch screen; thereby it is easy for the user to sense the physical key.

Abstract: Embodiments of the present disclosure provide a delay measurement method and an optical transport network device. The method includes: acquiring, according to delay information from a first optical transport network device to a second optical transport network device in an optical transport network, a delay of transporting service data from the first optical transport network device to the second optical transport network device; adjusting, according to the delay, residence time of the service data in the optical transport network so that the time is equal to a preset reference delay. Through the method of the present disclosure, uplink and downlink delays can be accurately measured, and the residence time of the service data in the optical transport network is adjusted to be consistent with the reference delay, thereby solving the problem in the prior art of inaccurate delay measurement resulting from asymmetry between uplink and downlink delays.