Abstract: Systems and methods are disclosed for debug session management. For example, methods may include receiving a request from a client device and, in response, identifying a set of instructions to be executed, wherein the set of instructions is associated with at least one breakpoint. The methods may include initiating execution of the set of instructions. The methods may include determining, based on a marker, that pausing execution of the set of instructions using a data structure is permitted, and responsive to this determination: pausing execution of the set of instructions before executing an instruction associated with a breakpoint, and updating the marker to indicate that execution of the set of instructions has paused using the data structure.

Abstract: Embodiments of the application provide a control channel transmission method, a network device, a network controller, and a terminal device, to avoid a resource collision between physical downlink control channels (PDCCHs) of a plurality of network devices. The method includes: receiving, by a first network device, resource group indication information sent by a network controller, where a resource indicated by the resource group indication information does not overlap a resource used by another network device; determining, by the first network device, a first search space based on a user equipment UE-specific search space and the resource group indication information; and sending, by the first network device, a first PDCCH to the terminal device through the first search space.

Abstract: The disclosed embodiments disclose techniques for managing a cloud-based distributed computing environment (CBDCE) that comprises multiple geographically-distributed compute nodes. Multiple services simultaneously execute on the CBDCE compute nodes, with each service comprising multiple service instances that simultaneously execute on multiple distinct compute nodes of the CBDCE. During operation, the system uses a distributed database to track the status of the CBDCE to ensure the ongoing stability and scalability of the CBDCE. Upon receiving a request that is associated with the configuration of the CBDCE, a service accesses CBDCE status information from the distributed database to respond to the request.

Abstract: The disclosed embodiments disclose techniques for journaling data received in a cloud-based distributed computing environment (CBDCE). Multiple services simultaneously execute on the CBDCE compute nodes, with each service comprising multiple service instances that simultaneously execute on multiple, distinct compute nodes of the CBDCE. The CBDCE includes a distributed database that enables coordination between the service instances of services that execute in the CBDCE; this distributed database also includes multiple distributed database instances that simultaneously executing on multiple different CBDCE compute nodes. During operation, a service instance executing on one of these compute nodes receives a client request. The service instance submits this client request to a distributed database instance and, in parallel, also submits the client request and its associated user data to a distributed journaling service.

Abstract: The disclosed embodiments disclose techniques for managing cloud-based storage using a time-series database. A distributed cloud data management system (DCDMS) manages objects stored in a cloud storage system. The DCDMS leverages a distributed time-series database to track objects accessed via the DCDMS. During operation, the DCDMS receives a request to access an object using a path identifier and an object identifier. The DCDMS determines from the path identifier that the request is associated with one of its supported extended capabilities, and uses the previously tracked object operations that are stored in the time-series database to determine the actual target bucket in the cloud storage system that contains the requested object; the target bucket that contains the object may be different from the bucket identified in the path identifier that is received. The object identifier is then used to access the requested object from the target bucket to service the request.

Abstract: Herein provided are peptide inhibitors and methods for treating polyglutamine (polyQ) diseases. Also disclosed are related compositions and kits for therapeutic use in the treatment of polyQ diseases.

Abstract: Lighting system having a plurality light emitting diodes, wherein each of the light emitting diodes is configured to output light in a predetermined color bands and is arranged in a corresponding group according to the predetermined color bands. A plurality of power output controllers, each of the plurality of power output controllers configured to output a predetermined power level to the corresponding group of light emitting diodes and a master controller coupled to the plurality of output controllers and operable to synchronize the plurality of output controllers. The master controller operable to receive data from a remote device indicating a desired duty cycle, cycle period, and phase shift of the output power relative to one another.

Abstract: Methods and apparatus for predicting favored wireless service areas for drones are disclosed. A controller for a drone includes a service area identifier to identify favored wireless service areas during a flight of the drone. The favored wireless service areas are predicted by a model developed remotely from the drone. The controller also includes a service area selector to select one of the favored wireless service areas during the flight. The controller also includes a route manager to adjust a flight path of the drone during the flight based on the selected one of the favored wireless service areas.

Abstract: Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.

Abstract: A method for use by an S-REDS may comprise quasi-omni broadcasting a multi-relay channel measurement request to one or more RDSs. The S-REDS may receive a first multi-relay channel measurement report from a first RDS of the one or more RDSs. The first multi-relay channel measurement report may contain first channel measurement information associated with a channel between the first RDS and the S-REDS. The S-REDS may further receive a second multi-relay channel measurement report from the first RDS of the one or more RDSs. The second multi-relay channel measurement report contains second channel measurement information associated with a channel between the first RDS of the one or more RDSs and a D-REDS.

Abstract: Hybrid automatic repeat request (HARQ) processes, indicators, and similar methods may be used improve new radio performance in a number of ways. For example HARQ processes may be retransmitted, even before a response is expected, a number of times. Separate acknowledgement may be provided for various code blocks within a single transport block. Multi-bit ACK/NACK signaling may be used to efficiently express the status of individual code blocks or groups of code blocks within a transmission block. Grantless transmissions may be acknowledged implicitly, e.g., via responses comprising downlink control information or sent via a physical hybrid automatic repeat request indicator channel.

Abstract: B-cell maturation antigen (BCMA) is expressed on malignant plasma cells. The present invention provides novel bispecific antibodies (bsAbs) that bind to both BCMA and CD3 and activate T cells via the CD3 complex in the presence of BCMA-expressing tumor cells. In certain embodiments, the bispecific antigen-binding molecules of the present invention are capable of inhibiting the growth of tumors expressing BCMA. The bispecific antigen-binding molecules of the invention are useful for the treatment of diseases and disorders in which an upregulated or induced BCMA-targeted immune response is desired and/or therapeutically beneficial. For example, the bispecific antibodies of the invention are useful for the treatment of various cancers, including multiple myeloma.

Abstract: The invention provides methods of inhibiting epigenetic gene silencing in a cell expressing NPM/ALK or decreasing NPM/ALK content in a cell, by contacting a cell with an agent capable of increasing the concentration of Stat5a protein or its functional analog. Further, the invention provides a method of treating malignancies expressing oncogenic kinase by administering to a patient affected with a malignancy an agent capable of increasing the concentration of Stat5a protein or its epigenetically silenced functional tumor suppressor analog in a malignant cell. Finally, it provides a method to diagnose malignancy and monitor patient's response to therapy by analysis of the degree of DNA methylation of the gene encoding for Stat5a or its analog, their mRNA, or protein.

Abstract: This application discloses an information transmission method, apparatus, and system, and belongs to the field of communications technologies. The method includes: generating, by a base station, amount indication information, where the amount indication information is used to indicate a maximum amount of downlink control information; sending, by the base station, the amount indication information to user equipment; receiving, by the user equipment, the amount indication information; and receiving, by the user equipment, downlink control information based on the amount indication information. In this application, the amount indication information is sent to the user equipment, so that the user equipment receives the downlink control information based on the amount indication information. This can resolve a problem that complexity of blind detection performed by the user equipment is relatively high, thereby reducing the complexity of the blind detection performed by the user equipment.

Abstract: An exemplary energy harvester includes a piezoelectric diaphragm, an eccentric mass that rotates in response to external motion, and a piezoelectric stress inducer coupled with the eccentric mass and the piezoelectric diaphragm. The piezoelectric stress inducer deforms the piezoelectric diaphragm in response to rotational motion of the eccentric mass, causing the piezoelectric diaphragm to generate electrical energy.

Abstract: As a web browser application executing on a computing renders a web application that contains a plurality of objects, the web browser application carries out, respectively for each object, a set of resource-consumption actions involving use of resources of the client device. Further, the web browser application dynamically manages operational states of the objects based on a cumulative resource-consumption of the web application, including (i) determining that the cumulative resource-consumption of the web application exceeds a defined limit, and (ii) responsive to the determining, transitioning at least one of the objects from a first operational state to a second operational state, where the object contributes less to the cumulative resource-consumption of the web application in the second operational state than in the first operational state.

Abstract: New radio download numerology allocation information may be obtained through master information block data, system information block data, radio resource control signals, or signals or a physical downlink numerology indication channel, and used along with a reference signal detected in a search space to obtain resource element positions in an antenna port reference signal in a resource block that belongs to a particular band slice according to a reference signal allocation scheme for a band slice numerology. A physical download control may then be decoded based upon one or more resource elements of the reference signal, allowing the connection of, e.g., an enhanced mobile broadband, massive machine type communication, or ultra-reliable/low-latency application to a communications network thereby. Alternatively, multiple physical downlink control channels may be blindly demodulated at each of a number calculated reference signal locations, and one channel selected based on passing a cyclic redundancy check.

Abstract: A water heater has a tank, a burner, and a heat exchanger within the tank interior volume that has three tubes. The burner exhausts gas into the first tube. The second tube is non-linear, and the third tube connects the first tube with the second tube. The cross-sectional area of the first tube is greater than the cross-sectional area of the third tube. The cross-sectional area of the third tube is greater than the cross-sectional area of the second tube.

Abstract: A liquid crystal composition containing one or more compounds of formula I, one or more compounds of formula II, and a compound of formula III. The liquid crystal composition provided in the present invention has a lower viscosity and can achieve a fast response while having a moderate dielectric anisotropy ??, an appropriate optical anisotropy ?n, and a high stability to heat and light. A liquid crystal display element or liquid crystal display comprising the liquid crystal composition has properties of a wider nematic phase temperature range, a suitable birefringence anisotropy, a very high resistivity, a good ultraviolet resistance, a high charge retention, and a low vapour pressure, etc.

Abstract: A motor starting state recognition method and device, and a motor. The method includes sampling the counter electromotive forces of any two phases of a motor, and calculating a linear counter electromotive force of the motor according to the counter electromotive forces of the two phases, acquiring a polarity flag bit of the motor, and determining the starting state of the motor according to the polarity flag bit and the linear counter electromotive force. The state of a motor before starting can be recognized effectively using the method, so that the problem where a motor may not be started normally or the success rate of starting is low under the condition of a favorable/dead wind is effectively solved, and the problem where a motor becomes severely worn out and has a shorter service life after frequent starting due to starting failure is avoided. Moreover, the method is simple and highly accurate, and the success rate and reliability of system starting are effectively improved.